ID   ADF_VITVI               Reviewed;         143 AA.
AC   Q8SAG3;
DT   27-JUN-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2002, sequence version 1.
DT   03-AUG-2022, entry version 84.
DE   RecName: Full=Actin-depolymerizing factor;
DE            Short=ADF;
OS   Vitis vinifera (Grape).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; Vitales; Vitaceae; Viteae; Vitis.
OX   NCBI_TaxID=29760;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RA   Thomas P., Schiefelbein J.W.;
RT   "Cloning and characterization of an actin depolymerizing factor gene from
RT   grape (Vitis vinifera L.) expressed during rooting in stem cuttings.";
RL   Plant Sci. 162:283-288(2002).
CC   -!- FUNCTION: Actin-depolymerizing protein. Severs actin filaments (F-
CC       actin) and binds to actin monomers (By similarity). {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the actin-binding proteins ADF family.
CC       {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AF440310; AAL79826.1; -; mRNA.
DR   RefSeq; NP_001268119.1; NM_001281190.1.
DR   AlphaFoldDB; Q8SAG3; -.
DR   SMR; Q8SAG3; -.
DR   STRING; 29760.VIT_07s0005g03310.t01; -.
DR   PRIDE; Q8SAG3; -.
DR   EnsemblPlants; Vitvi07g00595_t001; Vitvi07g00595_P001; Vitvi07g00595.
DR   GeneID; 100232871; -.
DR   Gramene; Vitvi07g00595_t001; Vitvi07g00595_P001; Vitvi07g00595.
DR   KEGG; vvi:100232871; -.
DR   eggNOG; KOG1735; Eukaryota.
DR   HOGENOM; CLU_094004_2_2_1; -.
DR   OrthoDB; 1370477at2759; -.
DR   ExpressionAtlas; Q8SAG3; baseline and differential.
DR   GO; GO:0015629; C:actin cytoskeleton; IEA:InterPro.
DR   GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR   GO; GO:0030042; P:actin filament depolymerization; IEA:InterPro.
DR   CDD; cd11286; ADF_cofilin_like; 1.
DR   Gene3D; 3.40.20.10; -; 1.
DR   InterPro; IPR002108; ADF-H.
DR   InterPro; IPR029006; ADF-H/Gelsolin-like_dom_sf.
DR   InterPro; IPR017904; ADF/Cofilin.
DR   PANTHER; PTHR11913; PTHR11913; 1.
DR   Pfam; PF00241; Cofilin_ADF; 1.
DR   SMART; SM00102; ADF; 1.
DR   PROSITE; PS51263; ADF_H; 1.
PE   2: Evidence at transcript level;
KW   Actin-binding.
FT   CHAIN           1..143
FT                   /note="Actin-depolymerizing factor"
FT                   /id="PRO_0000214937"
FT   DOMAIN          11..143
FT                   /note="ADF-H"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00599"
SQ   SEQUENCE   143 AA;  16551 MW;  69FC6D10C1E00D8C CRC64;
     MSFRGLNASS GMGVADHSKN TFLELKRKKV HRYVIFKIDE KKKEVVVEKT GGPAESFDEF
     AAALPENDCR YAVYDFDFVT SENCQKSKIF FIAWSPDSSR IRAKMLYATS KERFRRELDG
     VHYEIQATDP TEMDLEVLRE RAH