ADG3_SCHPO
ID ADG3_SCHPO Reviewed; 1131 AA.
AC O74851; P78777;
DT 13-APR-2004, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1998, sequence version 1.
DT 25-MAY-2022, entry version 96.
DE RecName: Full=Probable secreted beta-glucosidase adg3;
DE EC=3.2.1.-;
DE Flags: Precursor;
GN Name=adg3; ORFNames=SPCC18.01c, SPCC74.07c;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 848-1131.
RC STRAIN=PR745;
RX PubMed=9501991; DOI=10.1093/dnares/4.6.363;
RA Yoshioka S., Kato K., Nakai K., Okayama H., Nojima H.;
RT "Identification of open reading frames in Schizosaccharomyces pombe
RT cDNAs.";
RL DNA Res. 4:363-369(1997).
CC -!- FUNCTION: Cell surface beta-glucosidase involved in cell wall
CC biogenesis,. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the SUN family. {ECO:0000305}.
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DR EMBL; CU329672; CAA20837.1; -; Genomic_DNA.
DR EMBL; D89125; BAA13787.1; -; mRNA.
DR PIR; T41144; T41144.
DR PIR; T42367; T42367.
DR RefSeq; NP_588380.2; NM_001023371.2.
DR AlphaFoldDB; O74851; -.
DR STRING; 4896.SPCC18.01c.1; -.
DR CAZy; GH132; Glycoside Hydrolase Family 132.
DR PaxDb; O74851; -.
DR EnsemblFungi; SPCC18.01c.1; SPCC18.01c.1:pep; SPCC18.01c.
DR GeneID; 2539118; -.
DR KEGG; spo:SPCC18.01c; -.
DR PomBase; SPCC18.01c; adg3.
DR VEuPathDB; FungiDB:SPCC18.01c; -.
DR eggNOG; ENOG502QWHV; Eukaryota.
DR HOGENOM; CLU_279002_0_0_1; -.
DR InParanoid; O74851; -.
DR OMA; IPTEMET; -.
DR PRO; PR:O74851; -.
DR Proteomes; UP000002485; Chromosome III.
DR GO; GO:0009986; C:cell surface; NAS:PomBase.
DR GO; GO:0005829; C:cytosol; HDA:PomBase.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; HDA:PomBase.
DR GO; GO:0008422; F:beta-glucosidase activity; ISM:PomBase.
DR GO; GO:0071555; P:cell wall organization; IEA:UniProtKB-KW.
DR GO; GO:0000272; P:polysaccharide catabolic process; IEA:UniProtKB-KW.
DR InterPro; IPR005556; SUN.
DR Pfam; PF03856; SUN; 1.
PE 2: Evidence at transcript level;
KW Carbohydrate metabolism; Cell wall biogenesis/degradation; Glycoprotein;
KW Glycosidase; Hydrolase; Polysaccharide degradation; Reference proteome;
KW Secreted; Signal.
FT SIGNAL 1..23
FT /evidence="ECO:0000255"
FT CHAIN 24..1131
FT /note="Probable secreted beta-glucosidase adg3"
FT /id="PRO_0000033462"
FT REGION 609..819
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 893..918
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 977..1031
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CARBOHYD 58
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 123
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 252
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 551
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 593
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 631
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 689
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 766
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 806
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 857
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 920
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CONFLICT 848..850
FT /note="DAS -> MLV (in Ref. 2; BAA13787)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 1131 AA; 116772 MW; 9A3506989CBC2DCC CRC64;
MPSKIEKICL LLLGFTAASN VNAYSHRRAG DTLHHRHKHE KHNDLTDSSY EPLTLSYNDT
QIQQLQRRDT VQCAFPYGDK MVAVTPDEGN AGWAMSPDQY CTAGTWCPYA CEPGYLMGQW
DPNATSYTYP ESMYGGLYCN SDGVAVKPFP SKDYCYPGVG DLSVVDQTGD GIAFCQTVLP
GNEAMLIPTW VAPDSEQVLA VPDISYWDET AAHYYVNPPG VSTTDGCVWG TSANPYGNWA
PYVAGANMDE NNITYVKLGA NPIYLDDSYW STVKPTYGLA LECEGDTCSG LPCYVDPREN
GVQGCPEGSP IGAGGACFCV VGFQQGTTAK IVVVDYSEEM ASSSSSASAT ATSSAESSIA
TSPITSSSNV VSSISTSSMD SSAVSSYSVV QSSLASIISN AYIATSKSGL NSGVSTLLAS
PTSSSTFVTS LLRRSSIDGS ASSSSASLAV PTVSSSTTGS LHYKTTTTVW VTEVFTRYLG
DDSTPVTSSS IFSTATEATD TSVQTSSAIY DSSSTSNIQS SSSVYASSTG ALSSNSLSSS
TSSVSTSYIP NASSSVYASS TEALSSNSLS SSTSSASTSY IPSASSSYEV ASNSSDYYSQ
TVSSITASGT TSSTSEIVST PASNSNTGSL NGTSSFNVNS VGPSSSQTTP TSSSSITGSQ
SLKETSSPAY VSSTVSYTSS SVDSSSTYNS TGSSSSDSQS FSGTTYSDPT TTITSEVSSI
LSSPTSMQSS VSRPQSSGDA SGFNTIFTSI SQSSDGETSG YTISSNSSQN SASEPQTAFT
SSSSSATPTI TQSSISTSVS SQSSMNSSYS SPISSNSVTS STSIISSIAS SSYTSIPSIS
SIASSFFDAS GFTSIYNGTK AGFSSSFALA SNSESGASDV LSSTIAKPTF KFSTSNSGST
SYSIPSSSSR NEGTTSYSSN ITVTSSTLKP SLTSSVSTAS SYIASSASSN TLSTEPKTFS
SSSTLSESIS SINTNSLTVK PESSLSSSTT SGLTSSSSTI PSSTRSESNS ESASTSSASK
RSSSSTSLVQ SNPVKTVVSL ESYKFTTSKI SLVKNPTKTY TVTDVETNVV VQTHTVSYVE
HSTSYTWVHT TLYEYADVEA STKSTSEPSA KSKRNAVSTF ETVFLKSKSS A
