ID   DSE1_KLULA              Reviewed;         580 AA.
AC   Q6CNC8;
DT   01-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   25-MAY-2022, entry version 112.
DE   RecName: Full=Protein DSE1;
DE   AltName: Full=Daughter-specific expression protein 1;
GN   Name=DSE1; OrderedLocusNames=KLLA0E13585g;
OS   Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 /
OS   NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Kluyveromyces.
OX   NCBI_TaxID=284590;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: Involved in cell wall metabolism and required for the
CC       separation of the mother and daughter cells. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the WD repeat DSE1 family. {ECO:0000305}.
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DR   EMBL; CR382125; CAG99648.1; -; Genomic_DNA.
DR   RefSeq; XP_454561.1; XM_454561.1.
DR   AlphaFoldDB; Q6CNC8; -.
DR   SMR; Q6CNC8; -.
DR   STRING; 28985.XP_454561.1; -.
DR   EnsemblFungi; CAG99648; CAG99648; KLLA0_E13553g.
DR   GeneID; 2893717; -.
DR   KEGG; kla:KLLA0_E13553g; -.
DR   eggNOG; ENOG502QTST; Eukaryota.
DR   HOGENOM; CLU_033098_0_0_1; -.
DR   InParanoid; Q6CNC8; -.
DR   OMA; QCGNIIV; -.
DR   Proteomes; UP000000598; Chromosome E.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0071555; P:cell wall organization; IEA:UniProtKB-KW.
DR   Gene3D; 2.130.10.10; -; 1.
DR   InterPro; IPR011047; Quinoprotein_ADH-like_supfam.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR001680; WD40_repeat.
DR   SUPFAM; SSF50998; SSF50998; 1.
DR   PROSITE; PS50082; WD_REPEATS_2; 1.
DR   PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division; Cell wall biogenesis/degradation;
KW   Reference proteome; Repeat; WD repeat.
FT   CHAIN           1..580
FT                   /note="Protein DSE1"
FT                   /id="PRO_0000285348"
FT   REPEAT          102..141
FT                   /note="WD 1"
FT   REPEAT          170..209
FT                   /note="WD 2"
FT   REPEAT          222..261
FT                   /note="WD 3"
FT   REPEAT          333..370
FT                   /note="WD 4"
FT   REPEAT          373..412
FT                   /note="WD 5"
FT   REGION          497..534
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        497..520
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   580 AA;  65167 MW;  0C59E7EF05C38E81 CRC64;
     MYLLTINYSL QCKHYTKSNK KLYIAKIMTE FYRAPEIFRQ NAIIVKKSRR DISDDENSTI
     VRRNCKIEAS KLNSSLLRKV SGDLNDVIVT KKLKTDCWKL SEDTRDVTSM SLDRDTILLS
     TSQTSDNLQL FQLRNNEINE QARGGKLLHS LQTITVPGKS ILATDIMQSQ NNDTVVSFDD
     KVHDRILLSG HSDGYVNLIA TSIENGNAKI LRRFNHSKHL KVITDSMDSV DLATQIYNTS
     RSKPIRHLKT WNKHHFTSVI NDSLFVYDVN QQCKDPLYLN SFPGLEHVDV NPVNPFTFSL
     TGTKFGQSGI ALLDLRLGDG NGIRVPGPQD SNAESGKCYT SKWLDEYTVV NSVGKALKIW
     DIRYGKVRAH LLGHNGHVNS LDYDNEMKKI YSTDDQGLIM SWDIKDLKFT DQVMCCRPSH
     GIQSFGLPAD CVQNGNIIQS PDLERIGNKK HLGSHFVGLA DSHFISLQDQ ELRSYSVVDM
     PMVLPPPRNP LRLLESVSTE TKSEPPATMV YSSSDETTKD SSNSAFEDSE DTLEYEAHSP
     MTPALDSMFD GKTHSFDIPT IPLLSGIRRG SDATFVCEGL