DSE3_YEAST
ID DSE3_YEAST Reviewed; 430 AA.
AC Q08729; D6W2W4;
DT 18-APR-2006, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1996, sequence version 1.
DT 03-AUG-2022, entry version 131.
DE RecName: Full=Protein DSE3;
DE AltName: Full=Daughter specific expression protein 3;
GN Name=DSE3; OrderedLocusNames=YOR264W;
OS Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX NCBI_TaxID=559292;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=9153759;
RX DOI=10.1002/(sici)1097-0061(199704)13:5<483::aid-yea105>3.0.co;2-u;
RA Poirey R., Jauniaux J.-C.;
RT "Sequencing analysis of a 36.8 kb fragment of yeast chromosome XV reveals
RT 26 open reading frames including SEC63, CDC31, SUG2, GCD1, RBL2, PNT1, PAC1
RT and VPH1.";
RL Yeast 13:483-487(1997).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=9169874;
RA Dujon B., Albermann K., Aldea M., Alexandraki D., Ansorge W., Arino J.,
RA Benes V., Bohn C., Bolotin-Fukuhara M., Bordonne R., Boyer J., Camasses A.,
RA Casamayor A., Casas C., Cheret G., Cziepluch C., Daignan-Fornier B.,
RA Dang V.-D., de Haan M., Delius H., Durand P., Fairhead C., Feldmann H.,
RA Gaillon L., Galisson F., Gamo F.-J., Gancedo C., Goffeau A., Goulding S.E.,
RA Grivell L.A., Habbig B., Hand N.J., Hani J., Hattenhorst U., Hebling U.,
RA Hernando Y., Herrero E., Heumann K., Hiesel R., Hilger F., Hofmann B.,
RA Hollenberg C.P., Hughes B., Jauniaux J.-C., Kalogeropoulos A.,
RA Katsoulou C., Kordes E., Lafuente M.J., Landt O., Louis E.J., Maarse A.C.,
RA Madania A., Mannhaupt G., Marck C., Martin R.P., Mewes H.-W., Michaux G.,
RA Paces V., Parle-McDermott A.G., Pearson B.M., Perrin A., Pettersson B.,
RA Poch O., Pohl T.M., Poirey R., Portetelle D., Pujol A., Purnelle B.,
RA Ramezani Rad M., Rechmann S., Schwager C., Schweizer M., Sor F., Sterky F.,
RA Tarassov I.A., Teodoru C., Tettelin H., Thierry A., Tobiasch E.,
RA Tzermia M., Uhlen M., Unseld M., Valens M., Vandenbol M., Vetter I.,
RA Vlcek C., Voet M., Volckaert G., Voss H., Wambutt R., Wedler H.,
RA Wiemann S., Winsor B., Wolfe K.H., Zollner A., Zumstein E., Kleine K.;
RT "The nucleotide sequence of Saccharomyces cerevisiae chromosome XV.";
RL Nature 387:98-102(1997).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=24374639; DOI=10.1534/g3.113.008995;
RA Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL G3 (Bethesda) 4:389-398(2014).
RN [4]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=17322287; DOI=10.1101/gr.6037607;
RA Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F.,
RA Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J.,
RA Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J.,
RA Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D.,
RA LaBaer J.;
RT "Approaching a complete repository of sequence-verified protein-encoding
RT clones for Saccharomyces cerevisiae.";
RL Genome Res. 17:536-543(2007).
RN [5]
RP INDUCTION, AND DEVELOPMENTAL STAGE.
RX PubMed=11747810; DOI=10.1016/s0092-8674(01)00596-7;
RA Colman-Lerner A., Chin T.E., Brent R.;
RT "Yeast Cbk1 and Mob2 activate daughter-specific genetic programs to induce
RT asymmetric cell fates.";
RL Cell 107:739-750(2001).
RN [6]
RP INDUCTION.
RX PubMed=11309124; DOI=10.1046/j.1365-2958.2001.02388.x;
RA Doolin M.-T., Johnson A.L., Johnston L.H., Butler G.;
RT "Overlapping and distinct roles of the duplicated yeast transcription
RT factors Ace2p and Swi5p.";
RL Mol. Microbiol. 40:422-432(2001).
RN [7]
RP SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX PubMed=14562095; DOI=10.1038/nature02026;
RA Huh W.-K., Falvo J.V., Gerke L.C., Carroll A.S., Howson R.W.,
RA Weissman J.S., O'Shea E.K.;
RT "Global analysis of protein localization in budding yeast.";
RL Nature 425:686-691(2003).
RN [8]
RP LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
RX PubMed=14562106; DOI=10.1038/nature02046;
RA Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N.,
RA O'Shea E.K., Weissman J.S.;
RT "Global analysis of protein expression in yeast.";
RL Nature 425:737-741(2003).
RN [9]
RP PERIODIC EXPRESSION DURING CELL CYCLE.
RX PubMed=16278933; DOI=10.1002/yea.1302;
RA de Lichtenberg U., Wernersson R., Jensen T.S., Nielsen H.B., Fausboell A.,
RA Schmidt P., Hansen F.B., Knudsen S., Brunak S.;
RT "New weakly expressed cell cycle-regulated genes in yeast.";
RL Yeast 22:1191-1201(2005).
RN [10]
RP PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-395, AND IDENTIFICATION BY
RP MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=19779198; DOI=10.1126/science.1172867;
RA Holt L.J., Tuch B.B., Villen J., Johnson A.D., Gygi S.P., Morgan D.O.;
RT "Global analysis of Cdk1 substrate phosphorylation sites provides insights
RT into evolution.";
RL Science 325:1682-1686(2009).
CC -!- FUNCTION: May be involved in the establishment of the daughter fate.
CC -!- SUBCELLULAR LOCATION: Bud neck {ECO:0000269|PubMed:14562095}.
CC -!- DEVELOPMENTAL STAGE: Expressed in daughter cells.
CC {ECO:0000269|PubMed:11747810}.
CC -!- INDUCTION: Expressed periodically during cell division. Requires ACE2,
CC CBK1, MOB2 and SWI5. {ECO:0000269|PubMed:11309124,
CC ECO:0000269|PubMed:11747810}.
CC -!- MISCELLANEOUS: Present with 922 molecules/cell in log phase SD medium.
CC {ECO:0000269|PubMed:14562106}.
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DR EMBL; Z75171; CAA99486.1; -; Genomic_DNA.
DR EMBL; AY693175; AAT93194.1; -; Genomic_DNA.
DR EMBL; BK006948; DAA11030.1; -; Genomic_DNA.
DR PIR; S67161; S67161.
DR RefSeq; NP_014907.3; NM_001183683.3.
DR PDB; 6DEI; X-ray; 1.70 A; C/D=60-80.
DR PDBsum; 6DEI; -.
DR AlphaFoldDB; Q08729; -.
DR SMR; Q08729; -.
DR BioGRID; 34653; 83.
DR DIP; DIP-1997N; -.
DR IntAct; Q08729; 4.
DR MINT; Q08729; -.
DR STRING; 4932.YOR264W; -.
DR iPTMnet; Q08729; -.
DR MaxQB; Q08729; -.
DR PaxDb; Q08729; -.
DR PRIDE; Q08729; -.
DR EnsemblFungi; YOR264W_mRNA; YOR264W; YOR264W.
DR GeneID; 854437; -.
DR KEGG; sce:YOR264W; -.
DR SGD; S000005790; DSE3.
DR VEuPathDB; FungiDB:YOR264W; -.
DR eggNOG; ENOG502S2PC; Eukaryota.
DR HOGENOM; CLU_052222_0_0_1; -.
DR InParanoid; Q08729; -.
DR OMA; ICASKQI; -.
DR BioCyc; YEAST:G3O-33754-MON; -.
DR PRO; PR:Q08729; -.
DR Proteomes; UP000002311; Chromosome XV.
DR RNAct; Q08729; protein.
DR GO; GO:0005935; C:cellular bud neck; HDA:SGD.
DR GO; GO:0005737; C:cytoplasm; HDA:SGD.
DR GO; GO:0005634; C:nucleus; HDA:SGD.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
PE 1: Evidence at protein level;
KW 3D-structure; Cell cycle; Phosphoprotein; Reference proteome.
FT CHAIN 1..430
FT /note="Protein DSE3"
FT /id="PRO_0000233007"
FT MOD_RES 395
FT /note="Phosphoserine"
FT /evidence="ECO:0007744|PubMed:19779198"
FT HELIX 65..67
FT /evidence="ECO:0007829|PDB:6DEI"
SQ SEQUENCE 430 AA; 48099 MW; 1DDE7DF7CB42C71D CRC64;
MPRKFLGNKI EKNVDAVRPS SLTLTADDLK YIPPIPQDFE DEDDKVLRTS NGGNRLSKRF
GGTLKLKKRL ESVPELFLHD FKKRPRSQLE VIREKKFTDM QVPKGPVCPQ STILPLRERK
KVKSLPIQRK SLRRPTLSKP AVVQSLGHKT HSDHIIDKVF VSRPAPIVMP VKALTPINPV
SLMQTQTQDC CRKNKYGKSG SEILFDEILS AYENVSTSDS TALNSEIDRI IDICASKQIA
KKNEAFQVPY VVCPDDTETL FSSTTPKLKP VNSNTLNDVI SSPEYTTSGC STYSDQSNSD
EELSEVESIV WNTNKRTMRS SIVSESTSEE GYCTAAETLP STVSVEDLDI HNKLPKVAQT
SSCNTLLNKL SIRKLKKVIL DPPKIMHVMT FDDDSDDGDD NDDEDRALNI LQKKIDCIEI
ASCSSSIYSE
