ID   DSS1_CAEBR              Reviewed;          76 AA.
AC   A8XLU5;
DT   13-JUL-2010, integrated into UniProtKB/Swiss-Prot.
DT   15-JAN-2008, sequence version 1.
DT   03-AUG-2022, entry version 66.
DE   RecName: Full=Probable 26S proteasome complex subunit dss-1 {ECO:0000250|UniProtKB:Q95Y72};
DE   AltName: Full=Deleted in split hand/split foot protein 1 homolog {ECO:0000250|UniProtKB:Q95Y72};
GN   Name=dss-1 {ECO:0000312|EMBL:CAP33599.1}; ORFNames=CBG15145;
OS   Caenorhabditis briggsae.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6238;
RN   [1] {ECO:0000312|EMBL:CAP33599.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AF16;
RX   PubMed=14624247; DOI=10.1371/journal.pbio.0000045;
RA   Stein L.D., Bao Z., Blasiar D., Blumenthal T., Brent M.R., Chen N.,
RA   Chinwalla A., Clarke L., Clee C., Coghlan A., Coulson A., D'Eustachio P.,
RA   Fitch D.H.A., Fulton L.A., Fulton R.E., Griffiths-Jones S., Harris T.W.,
RA   Hillier L.W., Kamath R., Kuwabara P.E., Mardis E.R., Marra M.A.,
RA   Miner T.L., Minx P., Mullikin J.C., Plumb R.W., Rogers J., Schein J.E.,
RA   Sohrmann M., Spieth J., Stajich J.E., Wei C., Willey D., Wilson R.K.,
RA   Durbin R.M., Waterston R.H.;
RT   "The genome sequence of Caenorhabditis briggsae: a platform for comparative
RT   genomics.";
RL   PLoS Biol. 1:166-192(2003).
CC   -!- FUNCTION: Subunit of the 26S proteasome which plays a role in
CC       ubiquitin-dependent proteolysis. Has an essential role in oogenesis and
CC       larval growth. Required for intestinal function and default lifespan
CC       (By similarity). {ECO:0000250|UniProtKB:Q95Y72}.
CC   -!- SUBUNIT: Part of the 26S proteasome. {ECO:0000250|UniProtKB:P60896}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q95Y72}. Cytoplasm
CC       {ECO:0000250|UniProtKB:Q95Y72}. Note=Diffuse in cytoplasm.
CC       {ECO:0000250|UniProtKB:Q95Y72}.
CC   -!- SIMILARITY: Belongs to the DSS1/SEM1 family. {ECO:0000255}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; HE601055; CAP33599.1; -; Genomic_DNA.
DR   RefSeq; XP_002642875.1; XM_002642829.1.
DR   AlphaFoldDB; A8XLU5; -.
DR   STRING; 6238.CBG15145; -.
DR   EnsemblMetazoa; CBG15145.1; CBG15145.1; WBGene00035473.
DR   GeneID; 8584868; -.
DR   KEGG; cbr:CBG_15145; -.
DR   CTD; 8584868; -.
DR   WormBase; CBG15145; CBP23175; WBGene00035473; Cbr-dss-1.
DR   eggNOG; KOG4764; Eukaryota.
DR   HOGENOM; CLU_141774_1_2_1; -.
DR   InParanoid; A8XLU5; -.
DR   OMA; EDWVENE; -.
DR   OrthoDB; 1626076at2759; -.
DR   Proteomes; UP000008549; Chromosome III.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0000502; C:proteasome complex; IBA:GO_Central.
DR   GO; GO:0008541; C:proteasome regulatory particle, lid subcomplex; IEA:InterPro.
DR   GO; GO:0000724; P:double-strand break repair via homologous recombination; IBA:GO_Central.
DR   GO; GO:0009792; P:embryo development ending in birth or egg hatching; IEA:EnsemblMetazoa.
DR   GO; GO:0060429; P:epithelium development; IEA:EnsemblMetazoa.
DR   GO; GO:0050892; P:intestinal absorption; IEA:EnsemblMetazoa.
DR   GO; GO:0006406; P:mRNA export from nucleus; IEA:InterPro.
DR   GO; GO:0048477; P:oogenesis; IEA:EnsemblMetazoa.
DR   GO; GO:0040018; P:positive regulation of multicellular organism growth; IEA:EnsemblMetazoa.
DR   GO; GO:0031398; P:positive regulation of protein ubiquitination; IEA:EnsemblMetazoa.
DR   GO; GO:0043248; P:proteasome assembly; IEA:InterPro.
DR   GO; GO:0040025; P:vulval development; IEA:EnsemblMetazoa.
DR   InterPro; IPR007834; DSS1_SEM1.
DR   PANTHER; PTHR16771; PTHR16771; 1.
DR   Pfam; PF05160; DSS1_SEM1; 1.
DR   SMART; SM01385; DSS1_SEM1; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Developmental protein; Nucleus; Proteasome; Reference proteome.
FT   CHAIN           1..76
FT                   /note="Probable 26S proteasome complex subunit dss-1"
FT                   /id="PRO_0000395331"
FT   REGION          1..28
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          52..76
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        55..76
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   76 AA;  9012 MW;  C74394B451963FC3 CRC64;
     MSSTTVTKKD QKTVVEKKET EEEEFEEFPI QEWPERADGE DDEVNVWEDN WDDETHESEF
     SKQLKEELRK GGHPIA