ID   DTM1_ORYSJ              Reviewed;         112 AA.
AC   Q7XI45;
DT   08-JUN-2016, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2003, sequence version 1.
DT   03-AUG-2022, entry version 98.
DE   RecName: Full=Signal peptidase complex-like protein DTM1 {ECO:0000305};
DE   AltName: Full=Protein DEFECTIVE TAPETUM AND MEIOCYTES 1 {ECO:0000303|PubMed:22111585};
DE   Flags: Precursor;
GN   Name=DTM1 {ECO:0000303|PubMed:22111585};
GN   OrderedLocusNames=Os07g0622900 {ECO:0000312|EMBL:BAF22232.1},
GN   LOC_Os07g43010 {ECO:0000305};
GN   ORFNames=P0524E08.106 {ECO:0000312|EMBL:BAC79906.1};
OS   Oryza sativa subsp. japonica (Rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX   NCBI_TaxID=39947;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=16100779; DOI=10.1038/nature03895;
RG   International rice genome sequencing project (IRGSP);
RT   "The map-based sequence of the rice genome.";
RL   Nature 436:793-800(2005).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=18089549; DOI=10.1093/nar/gkm978;
RG   The rice annotation project (RAP);
RT   "The rice annotation project database (RAP-DB): 2008 update.";
RL   Nucleic Acids Res. 36:D1028-D1033(2008).
RN   [3]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA   Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA   Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA   Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA   Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT   "Improvement of the Oryza sativa Nipponbare reference genome using next
RT   generation sequence and optical map data.";
RL   Rice 6:4-4(2013).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=12869764; DOI=10.1126/science.1081288;
RG   The rice full-length cDNA consortium;
RT   "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT   japonica rice.";
RL   Science 301:376-379(2003).
RN   [5]
RP   FUNCTION, SUBCELLULAR LOCATION, DEVELOPMENTAL STAGE, AND DISRUPTION
RP   PHENOTYPE.
RX   PubMed=22111585; DOI=10.1111/j.1365-313x.2011.04864.x;
RA   Yi J., Kim S.R., Lee D.Y., Moon S., Lee Y.S., Jung K.H., Hwang I., An G.;
RT   "The rice gene DEFECTIVE TAPETUM AND MEIOCYTES 1 (DTM1) is required for
RT   early tapetum development and meiosis.";
RL   Plant J. 70:256-270(2012).
CC   -!- FUNCTION: Functions in tapetum development during early meiosis. May
CC       play a role in the endoplasmic reticulum (ER) membrane in the early
CC       stages of tapetum development in anthers. Seems to function after MSP1
CC       and before UDT1. {ECO:0000269|PubMed:22111585}.
CC   -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC       {ECO:0000269|PubMed:22111585}; Multi-pass membrane protein
CC       {ECO:0000255}.
CC   -!- DEVELOPMENTAL STAGE: During anther development highly expressed in
CC       tapetal cells at stages 6 and 7, and at lower levels in the pollen
CC       mother cells and meiocytes. {ECO:0000269|PubMed:22111585}.
CC   -!- DISRUPTION PHENOTYPE: Male sterility due to abnormal formation of the
CC       tapetum and development of pollen mother cells arrested at the early
CC       stages of meiotic prophase I. {ECO:0000269|PubMed:22111585}.
CC   -!- SIMILARITY: Belongs to the SPCS1 family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AP004341; BAC79906.1; -; Genomic_DNA.
DR   EMBL; AP008213; BAF22232.1; -; Genomic_DNA.
DR   EMBL; AP014963; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AK059960; BAG87241.1; -; mRNA.
DR   RefSeq; XP_015644694.1; XM_015789208.1.
DR   AlphaFoldDB; Q7XI45; -.
DR   SMR; Q7XI45; -.
DR   STRING; 39947.Q7XI45; -.
DR   PRIDE; Q7XI45; -.
DR   EnsemblPlants; Os07t0622900-01; Os07t0622900-01; Os07g0622900.
DR   GeneID; 4343951; -.
DR   Gramene; Os07t0622900-01; Os07t0622900-01; Os07g0622900.
DR   KEGG; osa:4343951; -.
DR   InParanoid; Q7XI45; -.
DR   OrthoDB; 1601556at2759; -.
DR   Proteomes; UP000000763; Chromosome 7.
DR   Proteomes; UP000059680; Chromosome 7.
DR   GO; GO:0005789; C:endoplasmic reticulum membrane; IDA:UniProtKB.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005787; C:signal peptidase complex; IEA:InterPro.
DR   GO; GO:0048658; P:anther wall tapetum development; IMP:UniProtKB.
DR   GO; GO:0009555; P:pollen development; IMP:UniProtKB.
DR   GO; GO:0006465; P:signal peptide processing; IEA:InterPro.
DR   InterPro; IPR039955; DTM1.
DR   InterPro; IPR009542; Spc1/SPCS1.
DR   InterPro; IPR006311; TAT_signal.
DR   PANTHER; PTHR38354; PTHR38354; 1.
DR   Pfam; PF06645; SPC12; 1.
PE   2: Evidence at transcript level;
KW   Endoplasmic reticulum; Membrane; Reference proteome; Signal; Transmembrane;
KW   Transmembrane helix.
FT   SIGNAL          1..25
FT                   /evidence="ECO:0000255"
FT   CHAIN           26..112
FT                   /note="Signal peptidase complex-like protein DTM1"
FT                   /id="PRO_0000436458"
FT   TRANSMEM        33..53
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        92..112
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   112 AA;  12628 MW;  87CB87CA68527A3A CRC64;
     MGRDEMLRRS LVALAAAVVV TGVVTASVRK AAATYGFGIL AIAGVLLPDW EFFDRDYSQW
     LTPMPASRRT AAEAAADREH DVWKFKPYPL RMAMLTTIYG FGLYKWWMYV SS