位置:首页 > 蛋白库 > DTPD_SALTY
DTPD_SALTY
ID   DTPD_SALTY              Reviewed;         493 AA.
AC   Q7CQY0;
DT   13-JUL-2010, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 103.
DE   RecName: Full=Dipeptide permease D {ECO:0000255|HAMAP-Rule:MF_01880};
GN   Name=dtpD {ECO:0000255|HAMAP-Rule:MF_01880}; OrderedLocusNames=STM0710;
OS   Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=99287;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LT2 / SGSC1412 / ATCC 700720;
RX   PubMed=11677609; DOI=10.1038/35101614;
RA   McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P.,
RA   Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D.,
RA   Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E.,
RA   Ryan E., Sun H., Florea L., Miller W., Stoneking T., Nhan M., Waterston R.,
RA   Wilson R.K.;
RT   "Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.";
RL   Nature 413:852-856(2001).
CC   -!- FUNCTION: Probable proton-dependent permease that transports
CC       dipeptides. {ECO:0000255|HAMAP-Rule:MF_01880}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01880}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01880}.
CC   -!- SIMILARITY: Belongs to the major facilitator superfamily. Proton-
CC       dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family. DtpD
CC       subfamily. {ECO:0000255|HAMAP-Rule:MF_01880}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AE006468; AAL19654.1; -; Genomic_DNA.
DR   RefSeq; NP_459695.1; NC_003197.2.
DR   RefSeq; WP_001041123.1; NC_003197.2.
DR   AlphaFoldDB; Q7CQY0; -.
DR   SMR; Q7CQY0; -.
DR   STRING; 99287.STM0710; -.
DR   PaxDb; Q7CQY0; -.
DR   EnsemblBacteria; AAL19654; AAL19654; STM0710.
DR   GeneID; 1252230; -.
DR   KEGG; stm:STM0710; -.
DR   PATRIC; fig|99287.12.peg.742; -.
DR   HOGENOM; CLU_004790_0_0_6; -.
DR   OMA; GMMMGLW; -.
DR   PhylomeDB; Q7CQY0; -.
DR   BioCyc; SENT99287:STM0710-MON; -.
DR   Proteomes; UP000001014; Chromosome.
DR   GO; GO:0005887; C:integral component of plasma membrane; IBA:GO_Central.
DR   GO; GO:0071916; F:dipeptide transmembrane transporter activity; IBA:GO_Central.
DR   GO; GO:0015333; F:peptide:proton symporter activity; IBA:GO_Central.
DR   GO; GO:0042937; F:tripeptide transmembrane transporter activity; IBA:GO_Central.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   CDD; cd17346; MFS_DtpA_like; 1.
DR   Gene3D; 1.20.1250.20; -; 1.
DR   HAMAP; MF_01880; PTR2_DtpD_subfam; 1.
DR   InterPro; IPR023777; AA/pep_transptr_DtpD.
DR   InterPro; IPR005279; Dipep/tripep_permease.
DR   InterPro; IPR020846; MFS_dom.
DR   InterPro; IPR036259; MFS_trans_sf.
DR   InterPro; IPR000109; POT_fam.
DR   InterPro; IPR018456; PTR2_symporter_CS.
DR   PANTHER; PTHR11654; PTHR11654; 1.
DR   Pfam; PF00854; PTR2; 1.
DR   SUPFAM; SSF103473; SSF103473; 1.
DR   TIGRFAMs; TIGR00924; yjdL_sub1_fam; 1.
DR   PROSITE; PS50850; MFS; 1.
DR   PROSITE; PS01022; PTR2_1; 1.
DR   PROSITE; PS01023; PTR2_2; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Membrane; Peptide transport;
KW   Protein transport; Reference proteome; Transmembrane; Transmembrane helix;
KW   Transport.
FT   CHAIN           1..493
FT                   /note="Dipeptide permease D"
FT                   /id="PRO_0000395300"
FT   TRANSMEM        14..34
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01880"
FT   TRANSMEM        49..69
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01880"
FT   TRANSMEM        91..111
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01880"
FT   TRANSMEM        138..158
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01880"
FT   TRANSMEM        167..187
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01880"
FT   TRANSMEM        212..232
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01880"
FT   TRANSMEM        235..255
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01880"
FT   TRANSMEM        267..287
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01880"
FT   TRANSMEM        312..332
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01880"
FT   TRANSMEM        344..364
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01880"
FT   TRANSMEM        379..399
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01880"
FT   TRANSMEM        413..433
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01880"
FT   TRANSMEM        458..478
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01880"
SQ   SEQUENCE   493 AA;  53818 MW;  99BB72668CB70EBF CRC64;
     MNKQASQPRA IYYVVALQIW EYFSFYGMRA LLILYLTNQL KYDDNHAYEL FSAYCSLVYV
     TPILGGYLAD KVLGNRMAVM LGAFLMAIGH LVLGASEIAP TFLYLSLAII VCGYGLFKSN
     ISCLLGELYQ PEDPRRDGGF SLLYAAGNIG SIVAPIACGY VQEEYSWAMG FALAAIGMLA
     GLVIFLCGNR HFTHTTGVNK AVLCARNYLL PNWGWLLILL VAAPLLITVL FWKEWSVYAL
     IVATAIGLVV LAKIYRQAQT AKQRKELGLI VTLTLFSMLF WAFAQQGGSS ISLYIDRFVN
     RDILGYSVPT AMFQSVNAFA VMLCGVVLAW LVKESVSGNR TVRIWGKFAL GLGLMSAGFC
     ILTLSARWSA AYGHSSMPLM VLGLAVMGFA ELFIDPVAMS QITRIDIPGV TGVLTGIYML
     LSGAIANYLA GVIADQTSQS AFDASGAVNY AINAYVDVFE QITWGALACV GVVLLIWLYQ
     SFKFKSRALA VES
 
 
维奥蛋白资源库 - 中文蛋白资源 CopyRight © 2010-2024