DUF6_ARATH
ID DUF6_ARATH Reviewed; 701 AA.
AC O22897;
DT 08-JUN-2016, integrated into UniProtKB/Swiss-Prot.
DT 01-JAN-1998, sequence version 1.
DT 25-MAY-2022, entry version 123.
DE RecName: Full=DUF724 domain-containing protein 6 {ECO:0000305};
DE Short=AtDUF6 {ECO:0000303|PubMed:19795213};
GN Name=DUF6 {ECO:0000303|PubMed:19795213};
GN OrderedLocusNames=At2g47230 {ECO:0000312|Araport:AT2G47230};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP FUNCTION, GENE FAMILY, NOMENCLATURE, SUBCELLULAR LOCATION, AND TISSUE
RP SPECIFICITY.
RX PubMed=19795213; DOI=10.1007/s11103-009-9551-5;
RA Cao X., Yang K.Z., Xia C., Zhang X.Q., Chen L.Q., Ye D.;
RT "Characterization of DUF724 gene family in Arabidopsis thaliana.";
RL Plant Mol. Biol. 72:61-73(2010).
CC -!- FUNCTION: May be involved in the polar growth of plant cells via
CC transportation of RNAs. {ECO:0000305|PubMed:19795213}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:19795213}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=1;
CC Comment=A number of isoforms are produced. According to EST
CC sequences. {ECO:0000305};
CC Name=1;
CC IsoId=O22897-1; Sequence=Displayed;
CC -!- TISSUE SPECIFICITY: Expressed in roots, stems and flowers.
CC {ECO:0000269|PubMed:19795213}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AK228604; Type=Miscellaneous discrepancy; Note=Sequencing errors.; Evidence={ECO:0000305};
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DR EMBL; AC002337; AAB63823.1; -; Genomic_DNA.
DR EMBL; CP002685; AEC10816.1; -; Genomic_DNA.
DR EMBL; AK228604; -; NOT_ANNOTATED_CDS; mRNA.
DR PIR; F84912; F84912.
DR RefSeq; NP_182245.1; NM_130291.3. [O22897-1]
DR AlphaFoldDB; O22897; -.
DR SMR; O22897; -.
DR STRING; 3702.AT2G47230.2; -.
DR PRIDE; O22897; -.
DR ProteomicsDB; 221879; -. [O22897-1]
DR EnsemblPlants; AT2G47230.1; AT2G47230.1; AT2G47230. [O22897-1]
DR GeneID; 819336; -.
DR Gramene; AT2G47230.1; AT2G47230.1; AT2G47230. [O22897-1]
DR KEGG; ath:AT2G47230; -.
DR Araport; AT2G47230; -.
DR eggNOG; ENOG502QTQX; Eukaryota.
DR HOGENOM; CLU_007138_1_0_1; -.
DR OMA; MTHEEEN; -.
DR PhylomeDB; O22897; -.
DR PRO; PR:O22897; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; O22897; baseline and differential.
DR GO; GO:0005634; C:nucleus; IDA:UniProtKB.
DR GO; GO:0040008; P:regulation of growth; IEA:UniProtKB-KW.
DR InterPro; IPR008395; Agenet-like_dom.
DR InterPro; IPR014002; Agenet_dom_plant.
DR InterPro; IPR007930; DUF724.
DR Pfam; PF05641; Agenet; 3.
DR Pfam; PF05266; DUF724; 1.
DR SMART; SM00743; Agenet; 4.
PE 2: Evidence at transcript level;
KW Alternative splicing; Coiled coil; Growth regulation; Nucleus;
KW Reference proteome; Transport.
FT CHAIN 1..701
FT /note="DUF724 domain-containing protein 6"
FT /id="PRO_0000436424"
FT DOMAIN 514..700
FT /note="DUF724"
FT /evidence="ECO:0000255"
FT REGION 299..353
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 374..452
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 626..670
FT /evidence="ECO:0000255"
FT COMPBIAS 299..315
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 322..336
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 379..402
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 403..448
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 701 AA; 79607 MW; F6B9527107002D48 CRC64;
MEETIRKGSE VEVSSTEEGF ADAWFRGILQ ENPTKSGRKK LRVRYLTLLN DDALSPLIEN
IEPRFIRPVP PENEYNGIVL EEGTVVDADH KDGWWTGVII KKLENGKFWV YYDSPPDIIE
FERNQLRPHL RWSGWKWLRP DIQELDKSMF SSGTMAEVST IVDKAEVAWF PAMIIKEIEV
DGEKKFIVKD CNKHLSFSGD EARTNSTIDS SRVRPTPPPF PVEKYELMDR VEVFRGSVWR
QGLVRGVLDH NCYMVCLVVT KEEPVVKHSD LRPCKVWEDG VWQDGPKQTP VIETPSNVMK
TKPMRSCSGA KSMTPKRTTK HARRSLNLEK SAETLTKAES RAATGELRSK RANDVINDNT
PLVITPQVKP IASVEPVTPS RVRTATPLKQ TKADTQGKSS PKKTLEPMRD ENGLENSTRQ
KVLEEKNSEK KGRKRKRQEE HNSDLKETDE SCNGQMAEIN DTSSICNDVD DQPLAAWINL
PTETSIDHSP IVVNNAAIAT DVEERQANDT LMILPFAKKS PFWKMYETQE VCKIAPQSPH
FSPLFEAKEE LREWTAVGMM VSFYGLLEEV KNLQLDVSPS TLGSLSCSFA ELEKHGFDVA
APQSRINKML SLQDERAKKA EERKGLEKKI EAGEIEGHTY EEEMAELELK ILELKRQQVV
AKEMKEATDK VTSGMKSYAE MINQEIEDLR LEFQSTASAP W
