ID   DUTL_HUMAN              Reviewed;         141 AA.
AC   Q6ZN92;
DT   10-JUN-2008, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 107.
DE   RecName: Full=Putative inactive deoxyuridine 5'-triphosphate nucleotidohydrolase-like protein FLJ16323;
DE            Short=dUTPase-like protein;
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Spleen;
RX   PubMed=14702039; DOI=10.1038/ng1285;
RA   Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R.,
RA   Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H.,
RA   Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.,
RA   Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K.,
RA   Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H.,
RA   Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M.,
RA   Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K.,
RA   Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T.,
RA   Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M.,
RA   Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S.,
RA   Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H.,
RA   Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K.,
RA   Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N.,
RA   Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S.,
RA   Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O.,
RA   Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H.,
RA   Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B.,
RA   Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y.,
RA   Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K.,
RA   Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T.,
RA   Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T.,
RA   Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y.,
RA   Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H.,
RA   Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y.,
RA   Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H.,
RA   Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O.,
RA   Isogai T., Sugano S.;
RT   "Complete sequencing and characterization of 21,243 full-length human
RT   cDNAs.";
RL   Nat. Genet. 36:40-45(2004).
CC   -!- SIMILARITY: Belongs to the dUTPase family. {ECO:0000305}.
CC   -!- CAUTION: Product of a dubious CDS prediction. Could be the remnant of
CC       an endogenous retroviral dUTPase. {ECO:0000305}.
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DR   EMBL; AK131322; BAD18483.1; -; mRNA.
DR   RefSeq; NP_001004352.1; NM_001004352.2.
DR   AlphaFoldDB; Q6ZN92; -.
DR   SMR; Q6ZN92; -.
DR   BioGRID; 137425; 2.
DR   IntAct; Q6ZN92; 2.
DR   iPTMnet; Q6ZN92; -.
DR   PhosphoSitePlus; Q6ZN92; -.
DR   BioMuta; -; -.
DR   DMDM; 74722930; -.
DR   PRIDE; Q6ZN92; -.
DR   DNASU; 100506422; -.
DR   GeneID; 100506422; -.
DR   DisGeNET; 100506422; -.
DR   neXtProt; NX_Q6ZN92; -.
DR   OrthoDB; 1444087at2759; -.
DR   PathwayCommons; Q6ZN92; -.
DR   BioGRID-ORCS; 100506422; 7 hits in 140 CRISPR screens.
DR   GenomeRNAi; 100506422; -.
DR   Pharos; Q6ZN92; Tdark.
DR   Proteomes; UP000005640; Unplaced.
DR   RNAct; Q6ZN92; protein.
DR   GO; GO:0004170; F:dUTP diphosphatase activity; IBA:GO_Central.
DR   GO; GO:0000287; F:magnesium ion binding; IBA:GO_Central.
DR   GO; GO:0006226; P:dUMP biosynthetic process; IBA:GO_Central.
DR   GO; GO:0046081; P:dUTP catabolic process; IBA:GO_Central.
DR   Gene3D; 2.70.40.10; -; 1.
DR   InterPro; IPR008181; dUTPase.
DR   InterPro; IPR029054; dUTPase-like.
DR   InterPro; IPR036157; dUTPase-like_sf.
DR   PANTHER; PTHR11241; PTHR11241; 1.
DR   Pfam; PF00692; dUTPase; 1.
DR   SUPFAM; SSF51283; SSF51283; 1.
PE   5: Uncertain;
KW   Reference proteome.
FT   CHAIN           1..141
FT                   /note="Putative inactive deoxyuridine 5'-triphosphate
FT                   nucleotidohydrolase-like protein FLJ16323"
FT                   /id="PRO_0000340657"
SQ   SEQUENCE   141 AA;  15492 MW;  E4F38288F374392D CRC64;
     MPVIPALGEA KGEVLPPGDT TTIIPLNWML KSPPGHFGLL LLLSQQAKNG VMVLAGVTDP
     EYQDEISLLL HNEGHLKEVK MEGARLGLPG RAESLEHQVQ SHLNMIAQSQ RTFQKKDAGK
     AIILSKLTQE QKTKHCMFSL H