ID   DVL23_ARATH             Reviewed;          45 AA.
AC   A8MRE9;
DT   02-JUN-2021, integrated into UniProtKB/Swiss-Prot.
DT   15-FEB-2017, sequence version 2.
DT   03-AUG-2022, entry version 56.
DE   RecName: Full=Small polypeptide DEVIL 23 {ECO:0000305};
DE   AltName: Full=Small polypeptide ROTUNDIFOLIA LIKE 13 {ECO:0000303|PubMed:15125775};
DE            Short=Small polypeptide ROT-FOUR-LIKE 13 {ECO:0000303|PubMed:15125775};
GN   Name=DVL23 {ECO:0000305}; Synonyms=RTFL13 {ECO:0000303|PubMed:15125775};
GN   OrderedLocusNames=At3g23635 {ECO:0000312|Araport:AT3G23635};
GN   ORFNames=MDB19 {ECO:0000312|EMBL:AB023036};
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=10819329; DOI=10.1093/dnares/7.2.131;
RA   Sato S., Nakamura Y., Kaneko T., Katoh T., Asamizu E., Tabata S.;
RT   "Structural analysis of Arabidopsis thaliana chromosome 3. I. Sequence
RT   features of the regions of 4,504,864 bp covered by sixty P1 and TAC
RT   clones.";
RL   DNA Res. 7:131-135(2000).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   GENE FAMILY, AND NOMENCLATURE.
RC   STRAIN=cv. Columbia;
RX   PubMed=14871303; DOI=10.1111/j.1365-313x.2003.01994.x;
RA   Wen J., Lease K.A., Walker J.C.;
RT   "DVL, a novel class of small polypeptides: overexpression alters
RT   Arabidopsis development.";
RL   Plant J. 37:668-677(2004).
RN   [4]
RP   GENE FAMILY.
RC   STRAIN=cv. Columbia, and cv. Landsberg erecta;
RX   PubMed=15125775; DOI=10.1111/j.1365-313x.2004.02078.x;
RA   Narita N.N., Moore S., Horiguchi G., Kubo M., Demura T., Fukuda H.,
RA   Goodrich J., Tsukaya H.;
RT   "Overexpression of a novel small peptide ROTUNDIFOLIA4 decreases cell
RT   proliferation and alters leaf shape in Arabidopsis thaliana.";
RL   Plant J. 38:699-713(2004).
RN   [5]
RP   REVIEW, GENE FAMILY, AND NOMENCLATURE.
RC   STRAIN=cv. Columbia;
RX   PubMed=25701405; DOI=10.1007/s10265-015-0703-1;
RA   Guo P., Yoshimura A., Ishikawa N., Yamaguchi T., Guo Y., Tsukaya H.;
RT   "Comparative analysis of the RTFL peptide family on the control of plant
RT   organogenesis.";
RL   J. Plant Res. 128:497-510(2015).
CC   -!- FUNCTION: Small polypeptide acting as a regulatory molecule which
CC       coordinates cellular responses required for differentiation, growth and
CC       development, probably by restricting polar cell proliferation in
CC       lateral organs and coordinating socket cell recruitment and
CC       differentiation at trichome sites. {ECO:0000250|UniProtKB:Q6X5V0}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:Q7XXN8};
CC       Single-pass membrane protein {ECO:0000255}.
CC   -!- SIMILARITY: Belongs to the DVL/RTFL small polypeptides family.
CC       {ECO:0000305}.
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DR   EMBL; AB023036; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; CP002686; AEE76791.2; -; Genomic_DNA.
DR   RefSeq; NP_001319626.1; NM_001338652.1.
DR   AlphaFoldDB; A8MRE9; -.
DR   STRING; 3702.AT3G23635.1; -.
DR   PaxDb; A8MRE9; -.
DR   PRIDE; A8MRE9; -.
DR   EnsemblPlants; AT3G23635.1; AT3G23635.1; AT3G23635.
DR   GeneID; 28719310; -.
DR   Gramene; AT3G23635.1; AT3G23635.1; AT3G23635.
DR   KEGG; ath:AT3G23635; -.
DR   Araport; AT3G23635; -.
DR   TAIR; locus:4010713770; AT3G23635.
DR   HOGENOM; CLU_3242847_0_0_1; -.
DR   OrthoDB; 1633040at2759; -.
DR   Proteomes; UP000006548; Chromosome 3.
DR   ExpressionAtlas; A8MRE9; baseline and differential.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; ISS:UniProtKB.
DR   GO; GO:0008285; P:negative regulation of cell population proliferation; ISS:UniProtKB.
DR   GO; GO:0048367; P:shoot system development; IEA:UniProt.
DR   InterPro; IPR012552; DVL.
DR   Pfam; PF08137; DVL; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Developmental protein; Membrane; Reference proteome;
KW   Transmembrane; Transmembrane helix.
FT   CHAIN           1..45
FT                   /note="Small polypeptide DEVIL 23"
FT                   /id="PRO_0000452791"
FT   TRANSMEM        22..39
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          13..44
FT                   /note="Required for DVL/RTFL small polypeptide activity"
FT                   /evidence="ECO:0000250|UniProtKB:Q7XXN8"
SQ   SEQUENCE   45 AA;  5820 MW;  BBAB6D1FA396FBC8 CRC64;
     MKMSERRVGS YRKSTLRCWD WCKEQRTRAY IIWRCLIFLL RWDDY