DVL24_ARATH
ID DVL24_ARATH Reviewed; 119 AA.
AC A8MS09;
DT 02-JUN-2021, integrated into UniProtKB/Swiss-Prot.
DT 04-DEC-2007, sequence version 1.
DT 03-AUG-2022, entry version 78.
DE RecName: Full=Small polypeptide DEVIL 24 {ECO:0000305};
DE AltName: Full=Small polypeptide ROTUNDIFOLIA LIKE 11 {ECO:0000303|PubMed:15125775};
DE Short=Small polypeptide ROT-FOUR-LIKE 11 {ECO:0000303|PubMed:15125775};
GN Name=DVL24 {ECO:0000305}; Synonyms=RTFL11 {ECO:0000303|PubMed:15125775};
GN OrderedLocusNames=At1g17235 {ECO:0000312|Araport:AT1G17235};
GN ORFNames=F20D23 {ECO:0000312|EMBL:AC007651};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 29-119.
RC STRAIN=cv. Columbia;
RX PubMed=16244158; DOI=10.1104/pp.105.063479;
RA Xiao Y.-L., Smith S.R., Ishmael N., Redman J.C., Kumar N., Monaghan E.L.,
RA Ayele M., Haas B.J., Wu H.C., Town C.D.;
RT "Analysis of the cDNAs of hypothetical genes on Arabidopsis chromosome 2
RT reveals numerous transcript variants.";
RL Plant Physiol. 139:1323-1337(2005).
RN [4]
RP GENE FAMILY, AND NOMENCLATURE.
RC STRAIN=cv. Columbia;
RX PubMed=14871303; DOI=10.1111/j.1365-313x.2003.01994.x;
RA Wen J., Lease K.A., Walker J.C.;
RT "DVL, a novel class of small polypeptides: overexpression alters
RT Arabidopsis development.";
RL Plant J. 37:668-677(2004).
RN [5]
RP GENE FAMILY.
RC STRAIN=cv. Columbia, and cv. Landsberg erecta;
RX PubMed=15125775; DOI=10.1111/j.1365-313x.2004.02078.x;
RA Narita N.N., Moore S., Horiguchi G., Kubo M., Demura T., Fukuda H.,
RA Goodrich J., Tsukaya H.;
RT "Overexpression of a novel small peptide ROTUNDIFOLIA4 decreases cell
RT proliferation and alters leaf shape in Arabidopsis thaliana.";
RL Plant J. 38:699-713(2004).
RN [6]
RP REVIEW, GENE FAMILY, AND NOMENCLATURE.
RC STRAIN=cv. Columbia;
RX PubMed=25701405; DOI=10.1007/s10265-015-0703-1;
RA Guo P., Yoshimura A., Ishikawa N., Yamaguchi T., Guo Y., Tsukaya H.;
RT "Comparative analysis of the RTFL peptide family on the control of plant
RT organogenesis.";
RL J. Plant Res. 128:497-510(2015).
CC -!- FUNCTION: Small polypeptide acting as a regulatory molecule which
CC coordinates cellular responses required for differentiation, growth and
CC development, probably by restricting polar cell proliferation in
CC lateral organs and coordinating socket cell recruitment and
CC differentiation at trichome sites. {ECO:0000250|UniProtKB:Q6X5V0}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:Q7XXN8};
CC Single-pass membrane protein {ECO:0000255}.
CC -!- SIMILARITY: Belongs to the DVL/RTFL small polypeptides family.
CC {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=EG506155; Type=Frameshift; Evidence={ECO:0000305};
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DR EMBL; AC007651; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CP002684; AEE29562.1; -; Genomic_DNA.
DR EMBL; EG506155; -; NOT_ANNOTATED_CDS; mRNA.
DR EMBL; EG521118; -; NOT_ANNOTATED_CDS; mRNA.
DR RefSeq; NP_001077552.1; NM_001084083.2.
DR AlphaFoldDB; A8MS09; -.
DR STRING; 3702.AT1G17235.1; -.
DR PaxDb; A8MS09; -.
DR PRIDE; A8MS09; -.
DR EnsemblPlants; AT1G17235.1; AT1G17235.1; AT1G17235.
DR GeneID; 5007700; -.
DR Gramene; AT1G17235.1; AT1G17235.1; AT1G17235.
DR KEGG; ath:AT1G17235; -.
DR Araport; AT1G17235; -.
DR TAIR; locus:4010713448; AT1G17235.
DR HOGENOM; CLU_167101_0_0_1; -.
DR OMA; IIRLCAT; -.
DR OrthoDB; 1795640at2759; -.
DR PhylomeDB; A8MS09; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; A8MS09; baseline and differential.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; ISS:UniProtKB.
DR GO; GO:0008285; P:negative regulation of cell population proliferation; ISS:UniProtKB.
PE 3: Inferred from homology;
KW Cell membrane; Developmental protein; Membrane; Reference proteome;
KW Transmembrane; Transmembrane helix.
FT CHAIN 1..119
FT /note="Small polypeptide DEVIL 24"
FT /id="PRO_0000452792"
FT TRANSMEM 96..113
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REGION 83..114
FT /note="Required for DVL/RTFL small polypeptide activity"
FT /evidence="ECO:0000250|UniProtKB:Q7XXN8"
FT CONFLICT 84
FT /note="F -> L (in Ref. 3; EG521118)"
FT /evidence="ECO:0000305"
FT CONFLICT 90
FT /note="S -> F (in Ref. 3; EG521118)"
FT /evidence="ECO:0000305"
FT CONFLICT 104
FT /note="L -> F (in Ref. 3; EG521118)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 119 AA; 13646 MW; ED4A0E56E287FFA3 CRC64;
MCIILHSCTA RLPQAQNLQI ELKQDQVQAS FKSNEKKNSI FIKLVSEKPM LINRRVESSN
LLHSNMGGFL AKKTNSNSKI RNSFTSKCTS LMKQQHARLC IIRLCATMLL RSYTDHDDY
