DVL4_ARATH
ID DVL4_ARATH Reviewed; 41 AA.
AC Q9SAF8;
DT 02-JUN-2021, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2000, sequence version 1.
DT 03-AUG-2022, entry version 113.
DE RecName: Full=Small polypeptide DEVIL 4 {ECO:0000303|PubMed:14871303};
DE AltName: Full=Small polypeptide ROTUNDIFOLIA like 17 {ECO:0000303|PubMed:15125775};
DE Short=Small polypeptide ROT-FOUR-LIKE 17 {ECO:0000303|PubMed:15125775};
GN Name=DVL4 {ECO:0000303|PubMed:14871303};
GN Synonyms=RTFL17 {ECO:0000303|PubMed:15125775};
GN OrderedLocusNames=At1g13245 {ECO:0000312|Araport:AT1G13245};
GN ORFNames=F3F19.27 {ECO:0000312|EMBL:AAD31077.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], FUNCTION, TISSUE SPECIFICITY, GENE FAMILY, AND
RP NOMENCLATURE.
RC STRAIN=cv. Columbia;
RX PubMed=14871303; DOI=10.1111/j.1365-313x.2003.01994.x;
RA Wen J., Lease K.A., Walker J.C.;
RT "DVL, a novel class of small polypeptides: overexpression alters
RT Arabidopsis development.";
RL Plant J. 37:668-677(2004).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Southwick A., Karlin-Neumann G., Nguyen M., Lam B., Miranda M., Palm C.J.,
RA Theologis A., Ecker J., Davis R.W.;
RL Submitted (NOV-2000) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.
RN [6]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Shinn P., Chen H., Kim C.J., Quinitio C., Ecker J.R.;
RT "Arabidopsis ORF clones.";
RL Submitted (MAY-2006) to the EMBL/GenBank/DDBJ databases.
RN [7]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN [8]
RP GENE FAMILY.
RC STRAIN=cv. Columbia, and cv. Landsberg erecta;
RX PubMed=15125775; DOI=10.1111/j.1365-313x.2004.02078.x;
RA Narita N.N., Moore S., Horiguchi G., Kubo M., Demura T., Fukuda H.,
RA Goodrich J., Tsukaya H.;
RT "Overexpression of a novel small peptide ROTUNDIFOLIA4 decreases cell
RT proliferation and alters leaf shape in Arabidopsis thaliana.";
RL Plant J. 38:699-713(2004).
RN [9]
RP FUNCTION.
RC STRAIN=cv. Columbia;
RX PubMed=22112938; DOI=10.1093/jxb/err378;
RA Valdivia E.R., Chevalier D., Sampedro J., Taylor I., Niederhuth C.E.,
RA Walker J.C.;
RT "DVL genes play a role in the coordination of socket cell recruitment and
RT differentiation.";
RL J. Exp. Bot. 63:1405-1412(2012).
RN [10]
RP REVIEW, GENE FAMILY, AND NOMENCLATURE.
RC STRAIN=cv. Columbia;
RX PubMed=25701405; DOI=10.1007/s10265-015-0703-1;
RA Guo P., Yoshimura A., Ishikawa N., Yamaguchi T., Guo Y., Tsukaya H.;
RT "Comparative analysis of the RTFL peptide family on the control of plant
RT organogenesis.";
RL J. Plant Res. 128:497-510(2015).
CC -!- FUNCTION: Small polypeptide acting as a regulatory molecule which
CC coordinates cellular responses required for differentiation, growth and
CC development, including leaves shape, pedicule elongation, inflorescence
CC organization and fruit maturation, probably by restricting polar cell
CC proliferation in lateral organs and coordinating socket cell
CC recruitment and differentiation at trichome sites.
CC {ECO:0000269|PubMed:14871303, ECO:0000269|PubMed:22112938}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:Q7XXN8};
CC Single-pass membrane protein {ECO:0000255}.
CC -!- TISSUE SPECIFICITY: Mostly expressed in leaves and, to a lower extent,
CC in roots, flowers and stems. {ECO:0000269|PubMed:14871303}.
CC -!- SIMILARITY: Belongs to the DVL/RTFL small polypeptides family.
CC {ECO:0000305}.
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DR EMBL; AY254320; AAP13819.1; -; mRNA.
DR EMBL; AC007357; AAD31077.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE28989.1; -; Genomic_DNA.
DR EMBL; AF325098; AAK17166.1; -; mRNA.
DR EMBL; AK221719; BAD95444.1; -; mRNA.
DR EMBL; BT025298; ABF47114.1; -; mRNA.
DR EMBL; AY085299; AAM67252.1; -; mRNA.
DR RefSeq; NP_683303.1; NM_148462.3.
DR AlphaFoldDB; Q9SAF8; -.
DR STRING; 3702.AT1G13245.1; -.
DR PaxDb; Q9SAF8; -.
DR PRIDE; Q9SAF8; -.
DR EnsemblPlants; AT1G13245.1; AT1G13245.1; AT1G13245.
DR GeneID; 837884; -.
DR Gramene; AT1G13245.1; AT1G13245.1; AT1G13245.
DR KEGG; ath:AT1G13245; -.
DR Araport; AT1G13245; -.
DR TAIR; locus:504956107; AT1G13245.
DR eggNOG; ENOG502SBME; Eukaryota.
DR HOGENOM; CLU_150897_5_1_1; -.
DR InParanoid; Q9SAF8; -.
DR OrthoDB; 1639820at2759; -.
DR PhylomeDB; Q9SAF8; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9SAF8; baseline and differential.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; ISS:UniProtKB.
DR GO; GO:0008285; P:negative regulation of cell population proliferation; ISS:UniProtKB.
DR GO; GO:0048367; P:shoot system development; IMP:TAIR.
DR InterPro; IPR012552; DVL.
DR Pfam; PF08137; DVL; 1.
PE 2: Evidence at transcript level;
KW Cell membrane; Developmental protein; Membrane; Reference proteome;
KW Transmembrane; Transmembrane helix.
FT CHAIN 1..41
FT /note="Small polypeptide DEVIL 4"
FT /id="PRO_0000452772"
FT TRANSMEM 10..29
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REGION 10..41
FT /note="Required for DVL/RTFL small polypeptide activity"
FT /evidence="ECO:0000250|UniProtKB:Q7XXN8"
SQ SEQUENCE 41 AA; 4719 MW; 495F143E3264B6B4 CRC64;
MKMGGSKRRV SSKGLGAVLK EQRAKLYIIR RCVVMLLCWH D
