DVL6_ARATH
ID DVL6_ARATH Reviewed; 40 AA.
AC Q6IM95;
DT 02-JUN-2021, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 1.
DT 03-AUG-2022, entry version 84.
DE RecName: Full=Small polypeptide DEVIL 6 {ECO:0000303|PubMed:14871303};
DE AltName: Full=Small polypeptide ROTUNDIFOLIA LIKE 16 {ECO:0000303|PubMed:15125775};
DE Short=Small polypeptide ROT-FOUR-LIKE 16 {ECO:0000303|PubMed:15125775};
GN Name=DVL6 {ECO:0000303|PubMed:14871303};
GN Synonyms=RTFL16 {ECO:0000303|PubMed:15125775};
GN OrderedLocusNames=At3g25717 {ECO:0000312|Araport:AT3G25717};
GN ORFNames=K13N2 {ECO:0000312|EMBL:AB028607};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], GENE FAMILY, AND NOMENCLATURE.
RC STRAIN=cv. Columbia;
RX PubMed=14871303; DOI=10.1111/j.1365-313x.2003.01994.x;
RA Wen J., Lease K.A., Walker J.C.;
RT "DVL, a novel class of small polypeptides: overexpression alters
RT Arabidopsis development.";
RL Plant J. 37:668-677(2004).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10819329; DOI=10.1093/dnares/7.2.131;
RA Sato S., Nakamura Y., Kaneko T., Katoh T., Asamizu E., Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 3. I. Sequence
RT features of the regions of 4,504,864 bp covered by sixty P1 and TAC
RT clones.";
RL DNA Res. 7:131-135(2000).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP GENE FAMILY.
RC STRAIN=cv. Columbia, and cv. Landsberg erecta;
RX PubMed=15125775; DOI=10.1111/j.1365-313x.2004.02078.x;
RA Narita N.N., Moore S., Horiguchi G., Kubo M., Demura T., Fukuda H.,
RA Goodrich J., Tsukaya H.;
RT "Overexpression of a novel small peptide ROTUNDIFOLIA4 decreases cell
RT proliferation and alters leaf shape in Arabidopsis thaliana.";
RL Plant J. 38:699-713(2004).
RN [5]
RP REVIEW, GENE FAMILY, AND NOMENCLATURE.
RC STRAIN=cv. Columbia;
RX PubMed=25701405; DOI=10.1007/s10265-015-0703-1;
RA Guo P., Yoshimura A., Ishikawa N., Yamaguchi T., Guo Y., Tsukaya H.;
RT "Comparative analysis of the RTFL peptide family on the control of plant
RT organogenesis.";
RL J. Plant Res. 128:497-510(2015).
CC -!- FUNCTION: Small polypeptide acting as a regulatory molecule which
CC coordinates cellular responses required for differentiation, growth and
CC development, probably by restricting polar cell proliferation in
CC lateral organs and coordinating socket cell recruitment and
CC differentiation at trichome sites. {ECO:0000250|UniProtKB:Q6X5V0}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:Q7XXN8};
CC Single-pass membrane protein {ECO:0000255}.
CC -!- SIMILARITY: Belongs to the DVL/RTFL small polypeptides family.
CC {ECO:0000305}.
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DR EMBL; BK001749; DAA02277.1; -; mRNA.
DR EMBL; AB028607; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CP002686; AEE77058.1; -; Genomic_DNA.
DR RefSeq; NP_850631.2; NM_180300.1.
DR AlphaFoldDB; Q6IM95; -.
DR STRING; 3702.AT3G25717.1; -.
DR PaxDb; Q6IM95; -.
DR PRIDE; Q6IM95; -.
DR EnsemblPlants; AT3G25717.1; AT3G25717.1; AT3G25717.
DR GeneID; 822160; -.
DR Gramene; AT3G25717.1; AT3G25717.1; AT3G25717.
DR KEGG; ath:AT3G25717; -.
DR Araport; AT3G25717; -.
DR TAIR; locus:1005716552; AT3G25717.
DR HOGENOM; CLU_150897_5_1_1; -.
DR InParanoid; Q6IM95; -.
DR OrthoDB; 1639820at2759; -.
DR PhylomeDB; Q6IM95; -.
DR Proteomes; UP000006548; Chromosome 3.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; ISS:UniProtKB.
DR GO; GO:0008285; P:negative regulation of cell population proliferation; ISS:UniProtKB.
DR GO; GO:0048367; P:shoot system development; ISS:TAIR.
DR InterPro; IPR012552; DVL.
DR Pfam; PF08137; DVL; 1.
PE 3: Inferred from homology;
KW Cell membrane; Developmental protein; Membrane; Reference proteome;
KW Transmembrane; Transmembrane helix.
FT CHAIN 1..40
FT /note="Small polypeptide DEVIL 6"
FT /id="PRO_0000452774"
FT TRANSMEM 12..28
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REGION 9..40
FT /note="Required for DVL/RTFL small polypeptide activity"
FT /evidence="ECO:0000250|UniProtKB:Q7XXN8"
SQ SEQUENCE 40 AA; 4620 MW; 84270C1D9517E6AB CRC64;
MGVLKRRVSS SRGLGGVLRE QRAKLYIIKR CVVMLLCWQD
