DVL9_ARATH
ID DVL9_ARATH Reviewed; 107 AA.
AC Q6IM92; Q8GXJ0;
DT 02-JUN-2021, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 1.
DT 25-MAY-2022, entry version 111.
DE RecName: Full=Small polypeptide DEVIL 9 {ECO:0000303|PubMed:14871303};
DE AltName: Full=Small polypeptide ROTUNDIFOLIA like 3 {ECO:0000303|PubMed:15125775};
DE Short=Small polypeptide ROT-FOUR-LIKE 3 {ECO:0000303|PubMed:15125775};
GN Name=DVL9 {ECO:0000303|PubMed:14871303};
GN Synonyms=RTFL3 {ECO:0000303|PubMed:15125775};
GN OrderedLocusNames=At1g07490 {ECO:0000312|Araport:AT1G07490};
GN ORFNames=F22G5.13 {ECO:0000312|EMBL:AC022464};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], GENE FAMILY, AND NOMENCLATURE.
RC STRAIN=cv. Columbia;
RX PubMed=14871303; DOI=10.1111/j.1365-313x.2003.01994.x;
RA Wen J., Lease K.A., Walker J.C.;
RT "DVL, a novel class of small polypeptides: overexpression alters
RT Arabidopsis development.";
RL Plant J. 37:668-677(2004).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=11910074; DOI=10.1126/science.1071006;
RA Seki M., Narusaka M., Kamiya A., Ishida J., Satou M., Sakurai T.,
RA Nakajima M., Enju A., Akiyama K., Oono Y., Muramatsu M., Hayashizaki Y.,
RA Kawai J., Carninci P., Itoh M., Ishii Y., Arakawa T., Shibata K.,
RA Shinagawa A., Shinozaki K.;
RT "Functional annotation of a full-length Arabidopsis cDNA collection.";
RL Science 296:141-145(2002).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Shinn P., Chen H., Kim C.J., Ecker J.R.;
RT "Arabidopsis ORF clones.";
RL Submitted (FEB-2006) to the EMBL/GenBank/DDBJ databases.
RN [6]
RP GENE FAMILY.
RC STRAIN=cv. Columbia, and cv. Landsberg erecta;
RX PubMed=15125775; DOI=10.1111/j.1365-313x.2004.02078.x;
RA Narita N.N., Moore S., Horiguchi G., Kubo M., Demura T., Fukuda H.,
RA Goodrich J., Tsukaya H.;
RT "Overexpression of a novel small peptide ROTUNDIFOLIA4 decreases cell
RT proliferation and alters leaf shape in Arabidopsis thaliana.";
RL Plant J. 38:699-713(2004).
RN [7]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=19376835; DOI=10.1104/pp.109.138677;
RA Reiland S., Messerli G., Baerenfaller K., Gerrits B., Endler A.,
RA Grossmann J., Gruissem W., Baginsky S.;
RT "Large-scale Arabidopsis phosphoproteome profiling reveals novel
RT chloroplast kinase substrates and phosphorylation networks.";
RL Plant Physiol. 150:889-903(2009).
RN [8]
RP FUNCTION.
RC STRAIN=cv. Columbia;
RX PubMed=22112938; DOI=10.1093/jxb/err378;
RA Valdivia E.R., Chevalier D., Sampedro J., Taylor I., Niederhuth C.E.,
RA Walker J.C.;
RT "DVL genes play a role in the coordination of socket cell recruitment and
RT differentiation.";
RL J. Exp. Bot. 63:1405-1412(2012).
RN [9]
RP REVIEW, GENE FAMILY, AND NOMENCLATURE.
RC STRAIN=cv. Columbia;
RX PubMed=25701405; DOI=10.1007/s10265-015-0703-1;
RA Guo P., Yoshimura A., Ishikawa N., Yamaguchi T., Guo Y., Tsukaya H.;
RT "Comparative analysis of the RTFL peptide family on the control of plant
RT organogenesis.";
RL J. Plant Res. 128:497-510(2015).
CC -!- FUNCTION: Small polypeptide acting as a regulatory molecule which
CC coordinates cellular responses required for differentiation, growth and
CC development, probably by restricting polar cell proliferation in
CC lateral organs and coordinating socket cell recruitment and
CC differentiation at trichome sites. {ECO:0000269|PubMed:22112938}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:Q7XXN8};
CC Single-pass membrane protein {ECO:0000255}.
CC -!- SIMILARITY: Belongs to the DVL/RTFL small polypeptides family.
CC {ECO:0000305}.
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DR EMBL; BK001752; DAA02280.1; -; mRNA.
DR EMBL; AC022464; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CP002684; AEE28135.1; -; Genomic_DNA.
DR EMBL; AK118212; BAC42834.1; -; mRNA.
DR EMBL; BT024668; ABD57493.1; -; mRNA.
DR RefSeq; NP_172229.2; NM_100623.2.
DR AlphaFoldDB; Q6IM92; -.
DR STRING; 3702.AT1G07490.1; -.
DR PaxDb; Q6IM92; -.
DR PRIDE; Q6IM92; -.
DR ProteomicsDB; 183111; -.
DR EnsemblPlants; AT1G07490.1; AT1G07490.1; AT1G07490.
DR GeneID; 837263; -.
DR Gramene; AT1G07490.1; AT1G07490.1; AT1G07490.
DR KEGG; ath:AT1G07490; -.
DR Araport; AT1G07490; -.
DR TAIR; locus:2024967; AT1G07490.
DR eggNOG; ENOG502S3XH; Eukaryota.
DR HOGENOM; CLU_150897_0_0_1; -.
DR InParanoid; Q6IM92; -.
DR OMA; PTHSHTE; -.
DR OrthoDB; 1638022at2759; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q6IM92; baseline and differential.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; ISS:UniProtKB.
DR GO; GO:0008285; P:negative regulation of cell population proliferation; ISS:UniProtKB.
DR GO; GO:0048367; P:shoot system development; ISS:TAIR.
DR InterPro; IPR012552; DVL.
DR Pfam; PF08137; DVL; 1.
PE 1: Evidence at protein level;
KW Cell membrane; Developmental protein; Membrane; Reference proteome;
KW Transmembrane; Transmembrane helix.
FT CHAIN 1..107
FT /note="Small polypeptide DEVIL 9"
FT /id="PRO_0000452777"
FT TRANSMEM 9..29
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REGION 1..79
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 73..104
FT /note="Required for DVL/RTFL small polypeptide activity"
FT /evidence="ECO:0000250|UniProtKB:Q7XXN8"
FT COMPBIAS 13..79
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 54
FT /note="V -> A (in Ref. 4; BAC42834)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 107 AA; 11693 MW; E0B716F3FDD2325A CRC64;
MDEKWRLSKK DALAASCSSS STSSKSKFSR SFSTSASSSK APAFVRSSST KCSVPSSSSS
SISRSSSKKE KGSITQKYSS LAKEQKGRFY IMRRCVAMLV CWHKHDS
