ID   ADHR_DROTE              Reviewed;         272 AA.
AC   P28486;
DT   01-DEC-1992, integrated into UniProtKB/Swiss-Prot.
DT   01-DEC-1992, sequence version 1.
DT   03-AUG-2022, entry version 78.
DE   RecName: Full=Alcohol dehydrogenase-related 31 kDa protein;
DE   Flags: Fragment;
GN   Name=Adhr; Synonyms=Adh-dup;
OS   Drosophila teissieri (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC   Drosophilidae; Drosophila; Sophophora.
OX   NCBI_TaxID=7243;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RA   Ashburner M.;
RL   Submitted (JUL-1990) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the short-chain dehydrogenases/reductases (SDR)
CC       family. {ECO:0000305}.
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DR   EMBL; X54118; CAA38061.1; -; Genomic_DNA.
DR   PIR; S20716; S20716.
DR   AlphaFoldDB; P28486; -.
DR   SMR; P28486; -.
DR   FlyBase; FBgn0013014; Dtei\Adhr.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   InterPro; IPR002427; ADH-rel.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR020904; Sc_DH/Rdtase_CS.
DR   InterPro; IPR002347; SDR_fam.
DR   Pfam; PF00106; adh_short; 1.
DR   PRINTS; PR01170; ADHRELATED.
DR   PRINTS; PR00080; SDRFAMILY.
DR   SUPFAM; SSF51735; SSF51735; 1.
DR   PROSITE; PS00061; ADH_SHORT; 1.
PE   3: Inferred from homology;
KW   Oxidoreductase.
FT   CHAIN           1..>272
FT                   /note="Alcohol dehydrogenase-related 31 kDa protein"
FT                   /id="PRO_0000054513"
FT   ACT_SITE        152
FT                   /note="Proton acceptor"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU10001"
FT   BINDING         11..34
FT                   /ligand="NAD(+)"
FT                   /ligand_id="ChEBI:CHEBI:57540"
FT                   /evidence="ECO:0000250"
FT   BINDING         139
FT                   /ligand="substrate"
FT                   /evidence="ECO:0000250"
FT   NON_TER         272
SQ   SEQUENCE   272 AA;  30302 MW;  0618BF70A2AC7248 CRC64;
     MFDLTGKHVC YVADCGGIAL ETSKVLMTKN IAKLAILQST ENPQAIAQLQ SIKPSTQIFF
     WTYDVTMARE EMKKYFDEVM VQMDYIDVLI NGATLCDENN IDATINTNLT GMMNTVATVL
     PYMDRQMGGS GGLIVNVTSV IGLDPSPVFC AYSASKFGVI GFTRSLADPL YYSQNGVAVM
     AVCCGPTRVF VDRELKAFLE YGQSFADRLR RAPCQSTSVC GQNIVNAIER SENGQIWIAD
     KGGLELVKLH WYWHMADQFL HYMQSNDEED QE