DYL2_CAEEL
ID DYL2_CAEEL Reviewed; 90 AA.
AC Q21557;
DT 01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT 21-DEC-2004, sequence version 2.
DT 03-AUG-2022, entry version 131.
DE RecName: Full=Probable dynein light chain 2, cytoplasmic;
GN Name=dlc-2; ORFNames=M18.2;
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bristol N2;
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
CC -!- FUNCTION: Acts as one of several non-catalytic accessory components of
CC a dynein complex. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the dynein light chain family. {ECO:0000305}.
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DR EMBL; Z68507; CAA92827.2; -; Genomic_DNA.
DR PIR; T23795; T23795.
DR RefSeq; NP_502298.2; NM_069897.4.
DR AlphaFoldDB; Q21557; -.
DR SMR; Q21557; -.
DR BioGRID; 52154; 1.
DR DIP; DIP-27196N; -.
DR STRING; 6239.M18.2; -.
DR EPD; Q21557; -.
DR PaxDb; Q21557; -.
DR PeptideAtlas; Q21557; -.
DR EnsemblMetazoa; M18.2.1; M18.2.1; WBGene00010888.
DR GeneID; 187460; -.
DR KEGG; cel:CELE_M18.2; -.
DR UCSC; M18.2; c. elegans.
DR CTD; 187460; -.
DR WormBase; M18.2; CE36658; WBGene00010888; dlc-2.
DR eggNOG; KOG3430; Eukaryota.
DR HOGENOM; CLU_070944_4_0_1; -.
DR InParanoid; Q21557; -.
DR OMA; QLGATWH; -.
DR OrthoDB; 1520814at2759; -.
DR PhylomeDB; Q21557; -.
DR Reactome; R-CEL-1632852; Macroautophagy.
DR Reactome; R-CEL-5620924; Intraflagellar transport.
DR Reactome; R-CEL-6798695; Neutrophil degranulation.
DR Reactome; R-CEL-6807878; COPI-mediated anterograde transport.
DR Reactome; R-CEL-6811436; COPI-independent Golgi-to-ER retrograde traffic.
DR Reactome; R-CEL-9646399; Aggrephagy.
DR PRO; PR:Q21557; -.
DR Proteomes; UP000001940; Chromosome IV.
DR Bgee; WBGene00010888; Expressed in larva and 3 other tissues.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005868; C:cytoplasmic dynein complex; IBA:GO_Central.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR GO; GO:0045505; F:dynein intermediate chain binding; IBA:GO_Central.
DR GO; GO:0007017; P:microtubule-based process; IEA:InterPro.
DR Gene3D; 3.30.740.10; -; 1.
DR InterPro; IPR037177; DLC_sf.
DR InterPro; IPR019763; Dynein_light_1/2_CS.
DR InterPro; IPR001372; Dynein_light_chain_typ-1/2.
DR PANTHER; PTHR11886; PTHR11886; 1.
DR Pfam; PF01221; Dynein_light; 1.
DR SMART; SM01375; Dynein_light; 1.
DR SUPFAM; SSF54648; SSF54648; 1.
DR PROSITE; PS01239; DYNEIN_LIGHT_1; 1.
PE 3: Inferred from homology;
KW Cytoplasm; Cytoskeleton; Dynein; Microtubule; Motor protein;
KW Reference proteome.
FT CHAIN 1..90
FT /note="Probable dynein light chain 2, cytoplasmic"
FT /id="PRO_0000195150"
SQ SEQUENCE 90 AA; 10486 MW; 424BE1018891E210 CRC64;
MSEEKIEVKE TDMEDPQRDM VISVVREAQR LYNIDKDVAA FVKEELDKKF GATWHVICGK
CFGSRVSYEM GHFILLKCNK VNVMIYKCGY