ID   DYM_CHICK               Reviewed;         669 AA.
AC   Q5ZLW3;
DT   05-JUL-2005, integrated into UniProtKB/Swiss-Prot.
DT   23-NOV-2004, sequence version 1.
DT   03-AUG-2022, entry version 90.
DE   RecName: Full=Dymeclin;
GN   Name=DYM; ORFNames=RCJMB04_4k4;
OS   Gallus gallus (Chicken).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC   Phasianinae; Gallus.
OX   NCBI_TaxID=9031;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=CB; TISSUE=Bursa of Fabricius;
RX   PubMed=15642098; DOI=10.1186/gb-2004-6-1-r6;
RA   Caldwell R.B., Kierzek A.M., Arakawa H., Bezzubov Y., Zaim J., Fiedler P.,
RA   Kutter S., Blagodatski A., Kostovska D., Koter M., Plachy J., Carninci P.,
RA   Hayashizaki Y., Buerstedde J.-M.;
RT   "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene
RT   function analysis.";
RL   Genome Biol. 6:R6.1-R6.9(2005).
CC   -!- FUNCTION: Necessary for correct organization of Golgi apparatus.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm. Golgi apparatus {ECO:0000250}.
CC       Note=Sequence analysis programs predict 1 transmembrane region.
CC       However, it has been shown in human that it is not a stably anchored
CC       transmembrane protein but it weakly associates with the Golgi apparatus
CC       and shuttles between the Golgi and the cytosol (By similarity).
CC       {ECO:0000250}.
CC   -!- PTM: Myristoylated in vitro; myristoylation is not essential for
CC       protein targeting to Golgi compartment. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the dymeclin family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AJ719621; CAG31280.1; -; mRNA.
DR   RefSeq; NP_001026569.1; NM_001031398.1.
DR   AlphaFoldDB; Q5ZLW3; -.
DR   STRING; 9031.ENSGALP00000038869; -.
DR   PaxDb; Q5ZLW3; -.
DR   Ensembl; ENSGALT00000068648; ENSGALP00000045334; ENSGALG00000037426.
DR   Ensembl; ENSGALT00000076834; ENSGALP00000050701; ENSGALG00000037426.
DR   Ensembl; ENSGALT00000100163; ENSGALP00000070923; ENSGALG00000037426.
DR   GeneID; 426843; -.
DR   KEGG; gga:426843; -.
DR   CTD; 54808; -.
DR   VEuPathDB; HostDB:geneid_426843; -.
DR   eggNOG; KOG2225; Eukaryota.
DR   GeneTree; ENSGT00390000008772; -.
DR   HOGENOM; CLU_013309_2_0_1; -.
DR   InParanoid; Q5ZLW3; -.
DR   OrthoDB; 982213at2759; -.
DR   PhylomeDB; Q5ZLW3; -.
DR   PRO; PR:Q5ZLW3; -.
DR   Proteomes; UP000000539; Chromosome Z.
DR   Bgee; ENSGALG00000037426; Expressed in skeletal muscle tissue and 13 other tissues.
DR   ExpressionAtlas; Q5ZLW3; baseline and differential.
DR   GO; GO:0005794; C:Golgi apparatus; IBA:GO_Central.
DR   GO; GO:0007030; P:Golgi organization; IBA:GO_Central.
DR   InterPro; IPR019142; Dymeclin.
DR   PANTHER; PTHR12895; PTHR12895; 1.
PE   2: Evidence at transcript level;
KW   Cytoplasm; Golgi apparatus; Lipoprotein; Myristate; Reference proteome.
FT   INIT_MET        1
FT                   /note="Removed"
FT                   /evidence="ECO:0000250"
FT   CHAIN           2..669
FT                   /note="Dymeclin"
FT                   /id="PRO_0000086882"
FT   LIPID           2
FT                   /note="N-myristoyl glycine"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   669 AA;  76161 MW;  A0221A92535579BC CRC64;
     MGANSSSISE LPDNEYLKKL SGAEPISEND PFWNQLLSFS FTTPTNSADL KLLEEATVSV
     CKSLVEKNPR TGNLGSLIKV FLSRTKELKI SAECQNHLFI WQAHNALFII CCLLKVFISR
     MSEEELQLHF TYEDKTPGSY GTECEDLIEE LLCCLIQLIV EIPLLDITYS ISLEAVTTLI
     VFLSCQLFHK EILRESLIHK YLMRGRCLPY TSRLVKTLLY NFIRQERSPP PGSHVFQQQT
     DGGGLLYGIA SGVATGLWTV FTLGGVGSKA TPQLDQCSPL ANQSLLLLLV LANLTDAPDT
     PNPYRQAIMS FKNTQDSSAF SSSHPHVFQI NFNSLYTALC EQQKSDQATL LLYMLLHQNG
     NVRTYVLART DIENLVLPIL EILYHVEERN SHHVYMALII LLILTEDDGF NRSIHEVILK
     NITWYAERVL TEISLGSLLI LVVIRTIQYN MTRTRDKYLH TNCLAALANM SAQFRSLHQY
     AAQRIISLFS LLSKKHNKVL EQATQSLRGS LDSNDSPLPD YAQDLNVIEE VIRMMLEIIN
     SCLTNSLHHN PNLVYALLYK RDLFEQFRTH PSFQDIMQNI DLVISFFSSR LEHAGAELSV
     ERVLEIIKQG AVALPKDRLR KFPELKFKYV EEEQPEEFFI PYVWSLVYNA AVALYWNPRD
     IQLFTMDSG