ID   DYM_XENTR               Reviewed;         669 AA.
AC   Q28BM0;
DT   03-MAR-2009, integrated into UniProtKB/Swiss-Prot.
DT   04-APR-2006, sequence version 1.
DT   03-AUG-2022, entry version 57.
DE   RecName: Full=Dymeclin;
GN   Name=dym; ORFNames=TEgg091g12.1;
OS   Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX   NCBI_TaxID=8364;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Egg;
RG   Sanger Xenopus tropicalis EST/cDNA project;
RL   Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=TGA IC; TISSUE=Testis;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (NOV-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Necessary for correct organization of Golgi apparatus.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm. Golgi apparatus {ECO:0000250}.
CC       Note=Sequence analysis programs predict 2 transmembrane regions.
CC       However, it has been shown in human that it is not a stably anchored
CC       transmembrane protein but it weakly associates with the Golgi apparatus
CC       and shuttles between the Golgi and the cytosol (By similarity).
CC       {ECO:0000250}.
CC   -!- PTM: Myristoylated in vitro; myristoylation is not essential for
CC       protein targeting to Golgi compartment. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the dymeclin family. {ECO:0000305}.
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DR   EMBL; CR942768; CAJ81458.1; -; mRNA.
DR   EMBL; BC154850; AAI54851.1; -; mRNA.
DR   RefSeq; NP_001039243.1; NM_001045778.2.
DR   AlphaFoldDB; Q28BM0; -.
DR   STRING; 8364.ENSXETP00000061382; -.
DR   PaxDb; Q28BM0; -.
DR   DNASU; 734107; -.
DR   GeneID; 734107; -.
DR   KEGG; xtr:734107; -.
DR   CTD; 54808; -.
DR   Xenbase; XB-GENE-5729291; dym.
DR   eggNOG; KOG2225; Eukaryota.
DR   InParanoid; Q28BM0; -.
DR   OrthoDB; 982213at2759; -.
DR   Proteomes; UP000008143; Chromosome 1.
DR   Proteomes; UP000790000; Unplaced.
DR   GO; GO:0005794; C:Golgi apparatus; IBA:GO_Central.
DR   GO; GO:0007030; P:Golgi organization; IBA:GO_Central.
DR   InterPro; IPR019142; Dymeclin.
DR   PANTHER; PTHR12895; PTHR12895; 1.
PE   2: Evidence at transcript level;
KW   Cytoplasm; Golgi apparatus; Lipoprotein; Myristate; Reference proteome.
FT   INIT_MET        1
FT                   /note="Removed"
FT                   /evidence="ECO:0000250"
FT   CHAIN           2..669
FT                   /note="Dymeclin"
FT                   /id="PRO_0000365014"
FT   LIPID           2
FT                   /note="N-myristoyl glycine"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   669 AA;  76158 MW;  20F6A3FE03B7244E CRC64;
     MGANSSTIKE LSENEFLKKL SGTDSISENE PFWNQLLSFS FSTPTNSADS KLLEEGTLSI
     CKSLIENNPR TGNLGALIRV FLSRTKELKI SAECQNQLFI WQAHNALFII CRLIKVFTSQ
     ISEEELLLHF TYRPADPGNY ESDTENLFEE LLFCLIQLIV EIPLLDLTYS ILLEAVTALI
     VLLSYQLFRK DILHESPIHR HLMKGPCLPY TSRLVKTLLY NFIRQEKSPP PGSHIFPQQQ
     DGGGLLYGLA SGVASGIWTV LTLGGVGSKP TPQQEQSSPL ANQSLLLLLV LSNLTDAPDC
     PNPFRQSVTF FRNTQDSSVS PTPNPHSFQI NFNSLYTALC EQQKSDQATL LLYTLLHQNS
     NVRTYVLARS DMENLVLPIL EILYHVEDRN SHHVYMALII LLILTEDDGF NRSIHEVILK
     NITWYTERVL TEISLGSLLI LVVIRTIQYN MTRTRDKYLH TNCLAALANM SAQFRSLHQY
     AAQRIISLFS LLSKKHNKVL EQATQSLRGS LGSDESPLPD YAQDLNVIEE VIRMMLEIIN
     SCLTNSLHHN PNMVYALLYK RELFEQFRSH PSFQDIMQNI DMVISFFSLR LEQAGADLSV
     ERVLEVIKQG AVALPKDRLR KFPELKFKYV EEEQPEEFFI PYAWSLVYHS GVGLYWNPQD
     IQLFTMDSG