ID   DYN3_ASHGO              Reviewed;         371 AA.
AC   Q751N0;
DT   26-JUN-2007, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 78.
DE   RecName: Full=Cytoplasmic dynein intermediate light chain DYN3;
DE            Short=Dynein protein 3;
GN   Name=DYN3; OrderedLocusNames=AGL333W;
OS   Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
OS   (Yeast) (Eremothecium gossypii).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Eremothecium.
OX   NCBI_TaxID=284811;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX   PubMed=15001715; DOI=10.1126/science.1095781;
RA   Dietrich F.S., Voegeli S., Brachat S., Lerch A., Gates K., Steiner S.,
RA   Mohr C., Poehlmann R., Luedi P., Choi S., Wing R.A., Flavier A.,
RA   Gaffney T.D., Philippsen P.;
RT   "The Ashbya gossypii genome as a tool for mapping the ancient Saccharomyces
RT   cerevisiae genome.";
RL   Science 304:304-307(2004).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX   PubMed=23749448; DOI=10.1534/g3.112.002881;
RA   Dietrich F.S., Voegeli S., Kuo S., Philippsen P.;
RT   "Genomes of Ashbya fungi isolated from insects reveal four mating-type
RT   loci, numerous translocations, lack of transposons, and distinct gene
RT   duplications.";
RL   G3 (Bethesda) 3:1225-1239(2013).
CC   -!- FUNCTION: Component of the cytoplasmic dynein which acts as a motor for
CC       the intracellular retrograde motility of vesicles and organelles along
CC       microtubules. May play an important role in the proper orientation of
CC       the mitotic spindle into the budding daughter cell yeast. Probably
CC       required for normal progression of the cell cycle (By similarity).
CC       {ECO:0000250}.
CC   -!- SUBUNIT: The cytoplasmic dynein is composed of at least two heavy
CC       chains and a number of intermediate and light chains. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the dynein light intermediate chain DYN3 family.
CC       {ECO:0000305}.
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DR   EMBL; AE016820; AAS54158.1; -; Genomic_DNA.
DR   RefSeq; NP_986334.1; NM_211396.1.
DR   AlphaFoldDB; Q751N0; -.
DR   STRING; 33169.AAS54158; -.
DR   PRIDE; Q751N0; -.
DR   EnsemblFungi; AAS54158; AAS54158; AGOS_AGL333W.
DR   GeneID; 4622627; -.
DR   KEGG; ago:AGOS_AGL333W; -.
DR   eggNOG; ENOG502S4QG; Eukaryota.
DR   HOGENOM; CLU_064762_0_0_1; -.
DR   InParanoid; Q751N0; -.
DR   OMA; QLERNTM; -.
DR   Proteomes; UP000000591; Chromosome VII.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0030286; C:dynein complex; IEA:UniProtKB-KW.
DR   GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR   InterPro; IPR022780; Dynein_light_int_chain.
DR   Pfam; PF05783; DLIC; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Cytoskeleton; Dynein; Microtubule; Motor protein;
KW   Reference proteome.
FT   CHAIN           1..371
FT                   /note="Cytoplasmic dynein intermediate light chain DYN3"
FT                   /id="PRO_0000292443"
SQ   SEQUENCE   371 AA;  41760 MW;  4EB99D57C0C95EC0 CRC64;
     MSSGNIWKQL LEENSEQLDQ STTETYVVCC ENEDSLNQFL QQCWQIDEGE KVTNLEPLGF
     FTKVVSRDEE NLRLNVYYAK SPLDAQTLQF LGVFLRQMET SQIRWIFLLD WLLDDKRLWL
     RQLRNSWAAL EEAQVAPFPG GAVVVVLNPS HVTQLERNTM VWNSRRLDLV HQTLRAACLN
     TGSALVTLDP NTAREDVMHI CALLAGLPTS RPVAMLSLQS LFIPHGADSI GKICTIAPEF
     PVATVFDNDF VSSTFEAAIA PELTPGPRVP SDHPWLTEPT NPPSEATAWH FDLQGRLATL
     YRHLGDSNKA ISVTQHRFHK PRSEDYAYEF ELPSKHPTIR DLIRSAAADS PNDVADSIDG
     LMDGIVQRNV H