E1BS_ADEC2
ID E1BS_ADEC2 Reviewed; 170 AA.
AC P35983;
DT 01-JUN-1994, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-1994, sequence version 1.
DT 12-AUG-2020, entry version 57.
DE RecName: Full=E1B protein, small T-antigen;
DE AltName: Full=E1B 19 kDa protein;
DE Short=E1B-19K;
OS Canine adenovirus serotype 2 (CAdV-2) (Canine adenovirus 2).
OC Viruses; Varidnaviria; Bamfordvirae; Preplasmiviricota; Tectiliviricetes;
OC Rowavirales; Adenoviridae; Mastadenovirus; Canine mastadenovirus A.
OX NCBI_TaxID=10514;
OH NCBI_TaxID=9615; Canis lupus familiaris (Dog) (Canis familiaris).
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=2623943; DOI=10.1016/0168-1702(89)90005-1;
RA Spibey N., McClory R.S., Cavanagh H.M.A.;
RT "Identification and nucleotide sequence of the early region 1 from canine
RT adenovirus types 1 and 2.";
RL Virus Res. 14:241-256(1989).
CC -!- SIMILARITY: Belongs to the adenoviridae E1B 19 kDa protein family.
CC {ECO:0000305}.
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DR PIR; D60010; D60010.
DR GO; GO:0019050; P:suppression by virus of host apoptotic process; IEA:UniProtKB-KW.
DR InterPro; IPR002924; Adenovir_t-Ag_E1B_19kDa.
DR InterPro; IPR002475; Bcl2-like.
DR Pfam; PF01691; Adeno_E1B_19K; 1.
DR PROSITE; PS50062; BCL2_FAMILY; 1.
PE 3: Inferred from homology;
KW Early protein; Host-virus interaction;
KW Inhibition of host apoptosis by viral BCL2-like protein;
KW Modulation of host cell apoptosis by virus.
FT CHAIN 1..170
FT /note="E1B protein, small T-antigen"
FT /id="PRO_0000221721"
SQ SEQUENCE 170 AA; 19366 MW; 01C21621735004DA CRC64;
MDPLKLENYL TFRAIIRGST LSPGFFRRWC FPALADVVGN IVVQEEGRFW QILPENHAFW
GLLRRGFTVA SFTEIITAAQ LENERLSRQL AFLAFISFLL RNWPSDSLVP EADRLDLVCA
PAWSRMQIWT QTARLINDLQ DSVLEEQGSA EEEECEEALL AGDSDDPLFG