ID   E1BS_ADECG              Reviewed;         169 AA.
AC   P35984;
DT   01-JUN-1994, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-1994, sequence version 1.
DT   02-JUN-2021, entry version 58.
DE   RecName: Full=E1B protein, small T-antigen;
DE   AltName: Full=E1B 19 kDa protein;
DE            Short=E1B-19K;
OS   Canine adenovirus serotype 1 (strain Glaxo) (CAdV-1) (Canine adenovirus 1
OS   (strain Glaxo)).
OC   Viruses; Varidnaviria; Bamfordvirae; Preplasmiviricota; Tectiliviricetes;
OC   Rowavirales; Adenoviridae; Mastadenovirus; Canine mastadenovirus A.
OX   NCBI_TaxID=10513;
OH   NCBI_TaxID=9615; Canis lupus familiaris (Dog) (Canis familiaris).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=2623943; DOI=10.1016/0168-1702(89)90005-1;
RA   Spibey N., McClory R.S., Cavanagh H.M.A.;
RT   "Identification and nucleotide sequence of the early region 1 from canine
RT   adenovirus types 1 and 2.";
RL   Virus Res. 14:241-256(1989).
CC   -!- SIMILARITY: Belongs to the adenoviridae E1B 19 kDa protein family.
CC       {ECO:0000305}.
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DR   PIR; C60010; C60010.
DR   GO; GO:0019050; P:suppression by virus of host apoptotic process; IEA:UniProtKB-KW.
DR   InterPro; IPR002924; Adenovir_t-Ag_E1B_19kDa.
DR   InterPro; IPR002475; Bcl2-like.
DR   Pfam; PF01691; Adeno_E1B_19K; 1.
DR   PROSITE; PS50062; BCL2_FAMILY; 1.
PE   3: Inferred from homology;
KW   Early protein; Host-virus interaction;
KW   Inhibition of host apoptosis by viral BCL2-like protein;
KW   Modulation of host cell apoptosis by virus.
FT   CHAIN           1..169
FT                   /note="E1B protein, small T-antigen"
FT                   /id="PRO_0000221718"
FT   REGION          147..169
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        151..169
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   169 AA;  19364 MW;  4B7F31A74136623F CRC64;
     MDPLKICENY LTFRSIIKGS TFSPGVFRRW RFHGLADVVG NIVEREEGRF WEIVPETHTL
     WAVFRGGFTV APFTEILTSL QLENRGRQLA FLAFLSFLLR NWPSDSVVSE DARLDLVCAP
     AWSRIQIWSQ AARLINDLPE SVFEGQGSVV EEEQGEEHLA RDSDDPFFD