ID   E1BS_ADECT              Reviewed;         169 AA.
AC   P14265; P87551;
DT   01-JAN-1990, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-2005, sequence version 2.
DT   12-AUG-2020, entry version 69.
DE   RecName: Full=E1B protein, small T-antigen;
DE   AltName: Full=E1B 19 kDa protein;
DE            Short=E1B-19K;
OS   Canine adenovirus serotype 2 (strain Toronto A 26-61) (CAdV-2) (Canine
OS   adenovirus 2 (strain Toronto A 26-61)).
OC   Viruses; Varidnaviria; Bamfordvirae; Preplasmiviricota; Tectiliviricetes;
OC   Rowavirales; Adenoviridae; Mastadenovirus; Canine mastadenovirus A.
OX   NCBI_TaxID=69152;
OH   NCBI_TaxID=9615; Canis lupus familiaris (Dog) (Canis familiaris).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=2800332; DOI=10.1016/0042-6822(89)90188-8;
RA   Shibata R., Shinagawa M., Iida Y., Tsukiyama T.;
RT   "Nucleotide sequence of E1 region of canine adenovirus type 2.";
RL   Virology 172:460-467(1989).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Campbell J.B., Zhao Y.;
RT   "Complete DNA sequence and genomic organization of canine adenovirus type
RT   2.";
RL   Submitted (DEC-1996) to the EMBL/GenBank/DDBJ databases.
RN   [3]
RP   GENOME ANNOTATION.
RX   PubMed=14573794; DOI=10.1099/vir.0.19497-0;
RA   Davison A.J., Benko M., Harrach B.;
RT   "Genetic content and evolution of adenoviruses.";
RL   J. Gen. Virol. 84:2895-2908(2003).
CC   -!- SIMILARITY: Belongs to the adenoviridae E1B 19 kDa protein family.
CC       {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAA42471.1; Type=Frameshift; Evidence={ECO:0000305};
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DR   EMBL; J04368; AAA42471.1; ALT_FRAME; Genomic_DNA.
DR   EMBL; U77082; AAB38712.1; -; Genomic_DNA.
DR   PIR; B34165; WMADN2.
DR   RefSeq; AP_000609.1; AC_000020.1.
DR   GO; GO:0019050; P:suppression by virus of host apoptotic process; IEA:UniProtKB-KW.
DR   InterPro; IPR002924; Adenovir_t-Ag_E1B_19kDa.
DR   InterPro; IPR002475; Bcl2-like.
DR   Pfam; PF01691; Adeno_E1B_19K; 1.
DR   PROSITE; PS50062; BCL2_FAMILY; 1.
PE   3: Inferred from homology;
KW   Early protein; Host-virus interaction;
KW   Inhibition of host apoptosis by viral BCL2-like protein;
KW   Modulation of host cell apoptosis by virus.
FT   CHAIN           1..169
FT                   /note="E1B protein, small T-antigen"
FT                   /id="PRO_0000221720"
SQ   SEQUENCE   169 AA;  19199 MW;  BB3ED4909DDA187E CRC64;
     MDPLKICENY LTFRAIIRGS TLSPGFFRRW CFPALADVVG NIVEQEEGRF WQILPENHAF
     WGLLRRGFTV ASFTEIITAA QLENRGRQLA FLAFISFLLR NWPSDSVVPE ADRLDLVCAP
     AWSRMQIWSQ TARLINDLQD SVLEEQGSAE EEECEEALLA GDSDDPLFG