E1BS_ADEM1
ID E1BS_ADEM1 Reviewed; 175 AA.
AC P12535;
DT 01-OCT-1989, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-1989, sequence version 1.
DT 02-JUN-2021, entry version 65.
DE RecName: Full=E1B protein, small T-antigen;
DE AltName: Full=E1B 19 kDa protein;
DE Short=E1B-19K;
OS Murine adenovirus A serotype 1 (MAdV-1) (Murine adenovirus 1).
OC Viruses; Varidnaviria; Bamfordvirae; Preplasmiviricota; Tectiliviricetes;
OC Rowavirales; Adenoviridae; Mastadenovirus; Murine mastadenovirus A.
OX NCBI_TaxID=10530;
OH NCBI_TaxID=10090; Mus musculus (Mouse).
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=3172335; DOI=10.1128/jvi.62.11.3947-3957.1988;
RA Ball A.O., Williams M.E., Spindler K.R.;
RT "Identification of mouse adenovirus type 1 early region 1: DNA sequence and
RT a conserved transactivating function.";
RL J. Virol. 62:3947-3957(1988).
CC -!- SIMILARITY: Belongs to the adenoviridae E1B 19 kDa protein family.
CC {ECO:0000305}.
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DR EMBL; M22245; AAA42428.1; -; Genomic_DNA.
DR PIR; B31158; Q1ADMA.
DR Proteomes; UP000243112; Genome.
DR GO; GO:0019050; P:suppression by virus of host apoptotic process; IEA:UniProtKB-KW.
DR InterPro; IPR002924; Adenovir_t-Ag_E1B_19kDa.
DR Pfam; PF01691; Adeno_E1B_19K; 1.
PE 3: Inferred from homology;
KW Early protein; Host-virus interaction;
KW Inhibition of host apoptosis by viral BCL2-like protein;
KW Modulation of host cell apoptosis by virus.
FT CHAIN 1..175
FT /note="E1B protein, small T-antigen"
FT /id="PRO_0000221709"
FT REGION 153..175
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 175 AA; 20000 MW; 775E1C64D3023129 CRC64;
MLPVYPFLAP VFDTFESTRA LFLEATLSLQ EPWWFRLLSF FRSPRYTGLA DVVRAIACER
EADFTAITPS SLIEDIAEGR FVMLVGLMEY LRFDTAGQGI VSFAFLSYLI DRVTKQSPLA
HFTVVEVVSL VVWRTVKLSR RRERRWVSQL STLAEEDEDE EGTTLTTEAE QESSA