ID   E1BS_ADES7              Reviewed;         180 AA.
AC   P06501;
DT   01-JAN-1988, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1988, sequence version 1.
DT   29-SEP-2021, entry version 59.
DE   RecName: Full=E1B protein, small T-antigen;
DE   AltName: Full=E1B 19 kDa protein;
DE            Short=E1B-19K;
OS   Simian adenovirus serotype 7 (SAdV-7) (Simian adenovirus 7).
OC   Viruses; Varidnaviria; Bamfordvirae; Preplasmiviricota; Tectiliviricetes;
OC   Rowavirales; Adenoviridae; Mastadenovirus.
OX   NCBI_TaxID=10532;
OH   NCBI_TaxID=9528; Cercopithecinae.
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=6092520; DOI=10.1099/0022-1317-65-10-1699;
RA   Dekker B.M.M., Konings D.A.M., Denisova T.S., Gibadulin R.A.,
RA   van Ormondt H.;
RT   "The nucleotide sequence of the leftmost XhoI fragment (6%) of simian
RT   adenovirus SA7P.";
RL   J. Gen. Virol. 65:1699-1708(1984).
CC   -!- SIMILARITY: Belongs to the adenoviridae E1B 19 kDa protein family.
CC       {ECO:0000305}.
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DR   EMBL; X01027; CAA25513.1; -; Genomic_DNA.
DR   GO; GO:0019050; P:suppression by virus of host apoptotic process; IEA:UniProtKB-KW.
DR   InterPro; IPR002924; Adenovir_t-Ag_E1B_19kDa.
DR   InterPro; IPR036834; Bcl-2-like_sf.
DR   InterPro; IPR002475; Bcl2-like.
DR   Pfam; PF01691; Adeno_E1B_19K; 1.
DR   SUPFAM; SSF56854; SSF56854; 1.
DR   PROSITE; PS50062; BCL2_FAMILY; 1.
PE   3: Inferred from homology;
KW   Early protein; Host-virus interaction;
KW   Inhibition of host apoptosis by viral BCL2-like protein;
KW   Modulation of host cell apoptosis by virus.
FT   CHAIN           1..180
FT                   /note="E1B protein, small T-antigen"
FT                   /id="PRO_0000221722"
FT   REGION          142..180
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        156..170
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   180 AA;  21280 MW;  C4C4FEB0F0BEBD2F CRC64;
     MDLRTALQTF ESTRRLLELC SNRTSFLWRW LFGTPLSRLV RQVKLEYEKD FERILDQCPG
     VFESLELGYH KVFEEKIVKE LDFSSPGRAV AAVAFASYLL DRWNTRTHLS PGYQMDYISL
     NLWKFWLRRR VYNYSRGLPQ LGPAAPLARQ GSQQEEQQQR QEEEQVQEEM RSGLDPPTEN