ADLO2_ARATH
ID ADLO2_ARATH Reviewed; 928 AA.
AC Q9M224;
DT 23-JAN-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2000, sequence version 1.
DT 03-AUG-2022, entry version 139.
DE RecName: Full=Protein ARABIDILLO 2;
GN OrderedLocusNames=At3g60350; ORFNames=T8B10.10;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130713; DOI=10.1038/35048706;
RA Salanoubat M., Lemcke K., Rieger M., Ansorge W., Unseld M., Fartmann B.,
RA Valle G., Bloecker H., Perez-Alonso M., Obermaier B., Delseny M.,
RA Boutry M., Grivell L.A., Mache R., Puigdomenech P., De Simone V.,
RA Choisne N., Artiguenave F., Robert C., Brottier P., Wincker P.,
RA Cattolico L., Weissenbach J., Saurin W., Quetier F., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Benes V., Wurmbach E., Drzonek H.,
RA Erfle H., Jordan N., Bangert S., Wiedelmann R., Kranz H., Voss H.,
RA Holland R., Brandt P., Nyakatura G., Vezzi A., D'Angelo M., Pallavicini A.,
RA Toppo S., Simionati B., Conrad A., Hornischer K., Kauer G., Loehnert T.-H.,
RA Nordsiek G., Reichelt J., Scharfe M., Schoen O., Bargues M., Terol J.,
RA Climent J., Navarro P., Collado C., Perez-Perez A., Ottenwaelder B.,
RA Duchemin D., Cooke R., Laudie M., Berger-Llauro C., Purnelle B., Masuy D.,
RA de Haan M., Maarse A.C., Alcaraz J.-P., Cottet A., Casacuberta E.,
RA Monfort A., Argiriou A., Flores M., Liguori R., Vitale D., Mannhaupt G.,
RA Haase D., Schoof H., Rudd S., Zaccaria P., Mewes H.-W., Mayer K.F.X.,
RA Kaul S., Town C.D., Koo H.L., Tallon L.J., Jenkins J., Rooney T., Rizzo M.,
RA Walts A., Utterback T., Fujii C.Y., Shea T.P., Creasy T.H., Haas B.,
RA Maiti R., Wu D., Peterson J., Van Aken S., Pai G., Militscher J.,
RA Sellers P., Gill J.E., Feldblyum T.V., Preuss D., Lin X., Nierman W.C.,
RA Salzberg S.L., White O., Venter J.C., Fraser C.M., Kaneko T., Nakamura Y.,
RA Sato S., Kato T., Asamizu E., Sasamoto S., Kimura T., Idesawa K.,
RA Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A.,
RA Muraki A., Nakayama S., Nakazaki N., Shinpo S., Takeuchi C., Wada T.,
RA Watanabe A., Yamada M., Yasuda M., Tabata S.;
RT "Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana.";
RL Nature 408:820-822(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP FUNCTION, SUBCELLULAR LOCATION, TISSUE SPECIFICITY, AND DEVELOPMENTAL
RP STAGE.
RX PubMed=16434475; DOI=10.1073/pnas.0507575103;
RA Coates J.C., Laplaze L., Haseloff J.;
RT "Armadillo-related proteins promote lateral root development in
RT Arabidopsis.";
RL Proc. Natl. Acad. Sci. U.S.A. 103:1621-1626(2006).
CC -!- FUNCTION: Promotes lateral root initiation and development,
CC independently of auxin (IAA) and abscisis acid (ABA).
CC {ECO:0000269|PubMed:16434475}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:16434475}.
CC -!- TISSUE SPECIFICITY: Expressed ubiquitously.
CC {ECO:0000269|PubMed:16434475}.
CC -!- DEVELOPMENTAL STAGE: Present in lateral root primordia.
CC {ECO:0000269|PubMed:16434475}.
CC -!- SIMILARITY: Belongs to the beta-catenin family. {ECO:0000305}.
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DR EMBL; AL138646; CAB81821.1; -; Genomic_DNA.
DR EMBL; CP002686; AEE80050.1; -; Genomic_DNA.
DR EMBL; CP002686; ANM65277.1; -; Genomic_DNA.
DR PIR; T47846; T47846.
DR RefSeq; NP_001319805.1; NM_001340041.1.
DR RefSeq; NP_191594.1; NM_115899.4.
DR AlphaFoldDB; Q9M224; -.
DR SMR; Q9M224; -.
DR STRING; 3702.AT3G60350.1; -.
DR PaxDb; Q9M224; -.
DR PRIDE; Q9M224; -.
DR EnsemblPlants; AT3G60350.1; AT3G60350.1; AT3G60350.
DR EnsemblPlants; AT3G60350.2; AT3G60350.2; AT3G60350.
DR GeneID; 825206; -.
DR Gramene; AT3G60350.1; AT3G60350.1; AT3G60350.
DR Gramene; AT3G60350.2; AT3G60350.2; AT3G60350.
DR KEGG; ath:AT3G60350; -.
DR Araport; AT3G60350; -.
DR TAIR; locus:2103351; AT3G60350.
DR eggNOG; ENOG502QRCG; Eukaryota.
DR HOGENOM; CLU_018807_0_0_1; -.
DR InParanoid; Q9M224; -.
DR OMA; NDIFSHW; -.
DR OrthoDB; 149274at2759; -.
DR PhylomeDB; Q9M224; -.
DR PRO; PR:Q9M224; -.
DR Proteomes; UP000006548; Chromosome 3.
DR ExpressionAtlas; Q9M224; baseline and differential.
DR Genevisible; Q9M224; AT.
DR GO; GO:0005634; C:nucleus; IDA:TAIR.
DR GO; GO:0048527; P:lateral root development; IMP:TAIR.
DR Gene3D; 1.25.10.10; -; 3.
DR Gene3D; 3.80.10.10; -; 1.
DR InterPro; IPR044583; ARABIDILLO1/2.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR000225; Armadillo.
DR InterPro; IPR001810; F-box_dom.
DR InterPro; IPR006553; Leu-rich_rpt_Cys-con_subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR PANTHER; PTHR46976; PTHR46976; 1.
DR Pfam; PF00514; Arm; 6.
DR Pfam; PF12937; F-box-like; 1.
DR SMART; SM00185; ARM; 8.
DR SMART; SM00256; FBOX; 1.
DR SMART; SM00367; LRR_CC; 2.
DR SUPFAM; SSF48371; SSF48371; 2.
DR PROSITE; PS50176; ARM_REPEAT; 6.
DR PROSITE; PS50181; FBOX; 1.
PE 2: Evidence at transcript level;
KW Nucleus; Reference proteome; Repeat; Ubl conjugation pathway.
FT CHAIN 1..928
FT /note="Protein ARABIDILLO 2"
FT /id="PRO_0000273538"
FT DOMAIN 37..83
FT /note="F-box"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00080"
FT REPEAT 147..186
FT /note="ARM 1"
FT REPEAT 237..278
FT /note="ARM 2"
FT REPEAT 303..341
FT /note="ARM 3"
FT REPEAT 370..409
FT /note="ARM 4"
FT REPEAT 419..458
FT /note="ARM 5"
FT REPEAT 460..499
FT /note="ARM 6"
FT REPEAT 501..543
FT /note="ARM 7"
FT REPEAT 545..585
FT /note="ARM 8"
FT REPEAT 591..630
FT /note="ARM 9"
FT REPEAT 632..674
FT /note="ARM 10"
FT REPEAT 676..715
FT /note="ARM 11"
FT REPEAT 717..757
FT /note="ARM 12"
FT REPEAT 824..864
FT /note="ARM 13"
FT MOTIF 3..8
FT /note="Nuclear localization signal"
FT /evidence="ECO:0000250"
SQ SEQUENCE 928 AA; 100745 MW; 444DD8E38CBD768E CRC64;
MSRRVRQRVE DNGKYKVDSP SYTVIGVEDL APKVQQYVNW TSLPYDTVFH LFTRLNYRDR
ASLASTCRTW RSLGASSFLW SSLDLRAHKF DLSMAASLAT RCVDLQKIRF RGVDSADAII
HLKARSLLEI SGDYCRKITD ATLSMIAARH EALESLQLGP DFCERITSDA IRVIAFCCPK
LKKLRVSGMR DVSSEAIESL AKHCPQLSDL GFLDCLNINE EALGKVVSLR YLSVAGTSNI
KWKVALENWE KLPKLIGLDV SRTTIDHIAV SRLLKSSQSL KVLCALNCPY LEEDKSYSSN
RFKGKVLLAV FTDTFDELAS IFADNSKKPK NIFSYWRDLI RKDKSIDEIM LWIEWIISHT
LLRIAESSNS QGLNDFWLNQ GATLLLSLMQ SAQEDVQERA ATGLATFIVV DDENASIDCG
RAEAVMRDGG IRLLLELAKS WREGLQSEAA KAIANLSVNA KVAKAVAEEG GISVLADLAK
SMNRLVAEEA AGGLWNLSVG EEHKNAIAQA GGVNALVDLI FRWPHGCDGV LERAAGALAN
LAADDKCSME VARAGGVHAL VMLARNCKYE GAQEQAARAL ANLAAHGDSN GNNAAVGQEA
GALEALVQLT QSPHEGVKQE AAGALWNLAF DDKNRESIAA FGGVEALVAL AKSSSNASTG
LQERVAGALW GLSVSEANSI AIGHEGGIPP LIALVRSEAE DVHETAAGAL WNLSFNPGNA
LRIVEEGGVV ALVQLCSSSV SKMARFMAAL ALAYMFDGRM DEYAMIGTSL ESTSKSVTLN
GARTMALDQI KAFIKTFMEH QIFSTGALSS APSMLAQVSE RARIPEAGHL RCSGSEIGRF
VTMLRNPCLV LRACAAFALL QFTIPESRHA MHHASLMQNA GEARGLRSAA AAASMPREAK
IFMKIVLRNL EHQQAESPEG MKVSYNRI
