ID   E311_ADE05              Reviewed;          93 AA.
AC   P17590;
DT   01-AUG-1990, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1990, sequence version 1.
DT   23-FEB-2022, entry version 84.
DE   RecName: Full=Early E3A 10.5 kDa glycoprotein;
OS   Human adenovirus C serotype 5 (HAdV-5) (Human adenovirus 5).
OC   Viruses; Varidnaviria; Bamfordvirae; Preplasmiviricota; Tectiliviricetes;
OC   Rowavirales; Adenoviridae; Mastadenovirus.
OX   NCBI_TaxID=28285;
OH   NCBI_TaxID=9606; Homo sapiens (Human).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=2981456; DOI=10.1016/0042-6822(85)90443-x;
RA   Cladaras C., Wold W.S.M.;
RT   "DNA sequence of the early E3 transcription unit of adenovirus 5.";
RL   Virology 140:28-43(1985).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=1727603; DOI=10.1016/0042-6822(92)90082-z;
RA   Chroboczek J., Bieber F., Jacrot B.;
RT   "The sequence of the genome of adenovirus type 5 and its comparison with
RT   the genome of adenovirus type 2.";
RL   Virology 186:280-285(1992).
CC   -!- SUBCELLULAR LOCATION: Host nucleus membrane; Single-pass membrane
CC       protein.
CC   -!- PTM: N-glycosylated and probably also O-glycosylated.
CC   -!- SIMILARITY: Belongs to the adenoviridae E3A-1 family. {ECO:0000305}.
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DR   EMBL; M73260; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; X03002; CAA26784.1; -; Genomic_DNA.
DR   PIR; A05245; ERAD53.
DR   RefSeq; AP_000221.2; AC_000008.1.
DR   SMR; P17590; -.
DR   Proteomes; UP000004992; Genome.
DR   GO; GO:0044200; C:host cell nuclear membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR008652; Adenovirus_Type-2_E3A.
DR   Pfam; PF05393; Hum_adeno_E3A; 1.
PE   3: Inferred from homology;
KW   Early protein; Glycoprotein; Host membrane; Host nucleus; Membrane;
KW   Transmembrane; Transmembrane helix.
FT   CHAIN           1..93
FT                   /note="Early E3A 10.5 kDa glycoprotein"
FT                   /id="PRO_0000221738"
FT   TRANSMEM        34..55
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        3
FT                   /note="N-linked (GlcNAc...) asparagine; by host"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   93 AA;  10523 MW;  008AD087AAB45A8F CRC64;
     MTNTTNAAAA TGLTSTTNTP QVSAFVNNWD NLGMWWFSIA LMFVCLIIMW LICCLKRKRA
     RPPIYSPIIV LHPNNDGIHR LDGLKHMFFS LTV