ID   E312_ADE05              Reviewed;         107 AA.
AC   P06496; Q6VGU1;
DT   01-JAN-1988, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1988, sequence version 1.
DT   29-SEP-2021, entry version 63.
DE   RecName: Full=Early E3A 12.5 kDa protein;
OS   Human adenovirus C serotype 5 (HAdV-5) (Human adenovirus 5).
OC   Viruses; Varidnaviria; Bamfordvirae; Preplasmiviricota; Tectiliviricetes;
OC   Rowavirales; Adenoviridae; Mastadenovirus.
OX   NCBI_TaxID=28285;
OH   NCBI_TaxID=9606; Homo sapiens (Human).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=2981456; DOI=10.1016/0042-6822(85)90443-x;
RA   Cladaras C., Wold W.S.M.;
RT   "DNA sequence of the early E3 transcription unit of adenovirus 5.";
RL   Virology 140:28-43(1985).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RA   Sugarman B.J., Hutchins B.M., McAllister D.L., Lu F., Thomas B.K.;
RT   "The complete nucleic acid sequence of the adenovirus type 5 reference
RT   material (ARM) Genome.";
RL   BioProcessing 2:27-33(2003).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=1727603; DOI=10.1016/0042-6822(92)90082-z;
RA   Chroboczek J., Bieber F., Jacrot B.;
RT   "The sequence of the genome of adenovirus type 5 and its comparison with
RT   the genome of adenovirus type 2.";
RL   Virology 186:280-285(1992).
RN   [4]
RP   IDENTIFICATION OF PROTEIN.
RX   PubMed=1585632; DOI=10.1016/0042-6822(92)90502-g;
RA   Hawkins L.K., Wold W.S.M.;
RT   "A 12,500 MW protein is coded by region E3 of adenovirus.";
RL   Virology 188:486-494(1992).
CC   -!- FUNCTION: Not yet known.
CC   -!- SIMILARITY: Belongs to the adenoviridae E3A-2 family. {ECO:0000305}.
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DR   EMBL; M73260; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; X03002; CAA26781.1; -; Genomic_DNA.
DR   EMBL; AY339865; AAQ19303.1; -; Genomic_DNA.
DR   PIR; A05244; ERAD51.
DR   RefSeq; AP_000218.1; AC_000008.1.
DR   Proteomes; UP000004992; Genome.
DR   Proteomes; UP000156915; Genome.
DR   InterPro; IPR007912; Adeno_E3A.
DR   Pfam; PF05248; Adeno_E3A; 1.
PE   3: Inferred from homology;
KW   Early protein.
FT   CHAIN           1..107
FT                   /note="Early E3A 12.5 kDa protein"
FT                   /id="PRO_0000221743"
FT   CONFLICT        88
FT                   /note="L -> P (in Ref. 2; AAQ19303)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   107 AA;  12347 MW;  0DBADCA0ACC0D09B CRC64;
     MLSGEAEQLR LKHLVHCRRH KCFARDSGEF CYFELPEDHI EGPAHGVRLT AQGELARSLI
     REFTQRPLLV ERDRGPCVLT VICNCPNLGL HQDLCCHLCA EYNKYRN