ID   E320_ADE1P              Reviewed;         181 AA.
AC   P35768;
DT   01-JUN-1994, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-1994, sequence version 1.
DT   02-DEC-2020, entry version 52.
DE   RecName: Full=Early E3 20.3 kDa glycoprotein;
OS   Human adenovirus B serotype 11 (strain Slobiski) (HAdV-11) (Human
OS   adenovirus 11P (strain Slobiski)).
OC   Viruses; Varidnaviria; Bamfordvirae; Preplasmiviricota; Tectiliviricetes;
OC   Rowavirales; Adenoviridae; Mastadenovirus; Human mastadenovirus B.
OX   NCBI_TaxID=343462;
OH   NCBI_TaxID=9606; Homo sapiens (Human).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=1413499; DOI=10.1016/0042-6822(92)90173-m;
RA   Mei Y.-F., Wadell G.;
RT   "The nucleotide sequence of adenovirus type 11 early 3 region: comparison
RT   of genome type Ad11p and Ad11a.";
RL   Virology 191:125-133(1992).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=12867636; DOI=10.1099/vir.0.19178-0;
RA   Mei Y.-F., Skog J., Lindman K., Wadell G.;
RT   "Comparative analysis of the genome organization of human adenovirus 11, a
RT   member of the human adenovirus species B, and the commonly used human
RT   adenovirus 5 vector, a member of species C.";
RL   J. Gen. Virol. 84:2061-2071(2003).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=12726735; DOI=10.1016/s0042-6822(02)00085-5;
RA   Stone D., Furthmann A., Sandig V., Lieber A.;
RT   "The complete nucleotide sequence, genome organization, and origin of human
RT   adenovirus type 11.";
RL   Virology 309:152-165(2003).
CC   -!- FUNCTION: E3 proteins seem to be dispensable for virus growth in tissue
CC       culture cells. They are potentially important for virus growth under
CC       special conditions; E3 region may help adenoviruses to evade the immune
CC       surveillance of the host.
CC   -!- SIMILARITY: Belongs to the adenoviridae E3_20 family. {ECO:0000305}.
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DR   EMBL; AF532578; AAP49189.1; -; Genomic_DNA.
DR   EMBL; AY163756; AAN62496.1; -; Genomic_DNA.
DR   PIR; B44057; B44057.
DR   InterPro; IPR003471; Adeno_E3_CR1.
DR   InterPro; IPR003470; Adeno_E3_CR2.
DR   Pfam; PF02440; Adeno_E3_CR1; 1.
DR   Pfam; PF02439; Adeno_E3_CR2; 1.
PE   3: Inferred from homology;
KW   Early protein; Glycoprotein.
FT   CHAIN           1..181
FT                   /note="Early E3 20.3 kDa glycoprotein"
FT                   /id="PRO_0000221754"
FT   CARBOHYD        29
FT                   /note="N-linked (GlcNAc...) asparagine; by host"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        57
FT                   /note="N-linked (GlcNAc...) asparagine; by host"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        70
FT                   /note="N-linked (GlcNAc...) asparagine; by host"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        75
FT                   /note="N-linked (GlcNAc...) asparagine; by host"
FT                   /evidence="ECO:0000255"
FT   CONFLICT        44
FT                   /note="A -> T (in Ref. 3; AAN62496)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   181 AA;  20335 MW;  27463F8991644CF6 CRC64;
     MASLTSLIFV SIVTAAHGQT VVSIPLGHNY TLIGPPITSE VIWAKLGSVD YFDIICNKTK
     PIIVTCNIQN LTLINVSKVY SGYYYGYDRY SSQYRNYLVR VTQLKTTKMP NMAKIRSDDN
     SLETFTSPTT PDEKNIPDSM IAIVAAVAVV MALIIICMLL YACRYKKFHP KKQDLLLRLN
     I