ID   E320_ADE35              Reviewed;         181 AA.
AC   P15137;
DT   01-APR-1990, integrated into UniProtKB/Swiss-Prot.
DT   01-APR-1990, sequence version 1.
DT   02-DEC-2020, entry version 53.
DE   RecName: Full=Early E3 20.3 kDa glycoprotein;
OS   Human adenovirus B serotype 35 (HAdV-35) (Human adenovirus 35).
OC   Viruses; Varidnaviria; Bamfordvirae; Preplasmiviricota; Tectiliviricetes;
OC   Rowavirales; Adenoviridae; Mastadenovirus; Human mastadenovirus B.
OX   NCBI_TaxID=10522;
OH   NCBI_TaxID=9606; Homo sapiens (Human).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=Holden;
RX   PubMed=3172347; DOI=10.1128/jvi.62.11.4431-4437.1988;
RA   Flomenberg P.R., Chen M., Horwitz M.S.;
RT   "Sequence and genetic organization of adenovirus type 35 early region 3.";
RL   J. Virol. 62:4431-4437(1988).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=Holden;
RX   PubMed=8666254; DOI=10.1016/0378-1119(95)00898-5;
RA   Basler C.F., Droguett G., Horwitz M.S.;
RT   "Sequence of the immunoregulatory early region 3 and flanking sequences of
RT   adenovirus type 35.";
RL   Gene 170:249-254(1996).
CC   -!- FUNCTION: E3 proteins seem to be dispensable for virus growth in tissue
CC       culture cells. They are potentially important for virus growth under
CC       special conditions; E3 region may help adenoviruses to evade the immune
CC       surveillance of the host.
CC   -!- SIMILARITY: Belongs to the adenoviridae E3_20 family. {ECO:0000305}.
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DR   EMBL; M23195; AAA42437.1; -; Genomic_DNA.
DR   EMBL; U32664; AAA75326.1; -; Genomic_DNA.
DR   PIR; C31162; ERAD23.
DR   RefSeq; AP_000595.1; AC_000019.1.
DR   InterPro; IPR003471; Adeno_E3_CR1.
DR   InterPro; IPR003470; Adeno_E3_CR2.
DR   Pfam; PF02440; Adeno_E3_CR1; 1.
DR   Pfam; PF02439; Adeno_E3_CR2; 1.
PE   3: Inferred from homology;
KW   Early protein; Glycoprotein.
FT   CHAIN           1..181
FT                   /note="Early E3 20.3 kDa glycoprotein"
FT                   /id="PRO_0000221755"
FT   CARBOHYD        29
FT                   /note="N-linked (GlcNAc...) asparagine; by host"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        57
FT                   /note="N-linked (GlcNAc...) asparagine; by host"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        70
FT                   /note="N-linked (GlcNAc...) asparagine; by host"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        75
FT                   /note="N-linked (GlcNAc...) asparagine; by host"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   181 AA;  20365 MW;  26FD3F2990644CE6 CRC64;
     MASLTSLIFV SIVTAAHGQT VVSIPLGHNY TLIGPPITSE VIWTKLGSVD YFDIICNKTK
     PIIVTCNIQN LTLINVSKVY SGYYYGYDRY SSQYRNYLVR VTQLKTTKMP NMAKIRSDDN
     SLETFTSPTT PDEKNIPDSM IAIVAAVAVV MALIIICMLL YACRYKKFHP KKQDLLLRLN
     I