ID   E321_ADE03              Reviewed;         189 AA.
AC   P11322;
DT   01-JUL-1989, integrated into UniProtKB/Swiss-Prot.
DT   01-JUL-1989, sequence version 1.
DT   02-DEC-2020, entry version 49.
DE   RecName: Full=Early E3 20.5 kDa glycoprotein;
OS   Human adenovirus B serotype 3 (HAdV-3) (Human adenovirus 3).
OC   Viruses; Varidnaviria; Bamfordvirae; Preplasmiviricota; Tectiliviricetes;
OC   Rowavirales; Adenoviridae; Mastadenovirus; Human mastadenovirus B.
OX   NCBI_TaxID=45659;
OH   NCBI_TaxID=9606; Homo sapiens (Human).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=3582978; DOI=10.1016/0378-1119(86)90322-7;
RA   Signaes C., Akusjaervi G., Pettersson U.;
RT   "Region E3 of human adenoviruses; differences between the oncogenic
RT   adenovirus-3 and the non-oncogenic adenovirus-2.";
RL   Gene 50:173-184(1986).
CC   -!- FUNCTION: E3 proteins seem to be dispensable for virus growth in tissue
CC       culture cells. They are potentially important for virus growth under
CC       special conditions; E3 region may help adenoviruses to evade the immune
CC       surveillance of the host.
CC   -!- SIMILARITY: Belongs to the adenoviridae E3_20 family. {ECO:0000305}.
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DR   EMBL; M15952; AAA42485.1; -; Genomic_DNA.
DR   PIR; F29500; ERAD35.
DR   InterPro; IPR003471; Adeno_E3_CR1.
DR   InterPro; IPR003470; Adeno_E3_CR2.
DR   Pfam; PF02440; Adeno_E3_CR1; 1.
DR   Pfam; PF02439; Adeno_E3_CR2; 1.
PE   3: Inferred from homology;
KW   Early protein; Glycoprotein.
FT   CHAIN           1..189
FT                   /note="Early E3 20.5 kDa glycoprotein"
FT                   /id="PRO_0000221756"
FT   CARBOHYD        73
FT                   /note="N-linked (GlcNAc...) asparagine; by host"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        137
FT                   /note="N-linked (GlcNAc...) asparagine; by host"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   189 AA;  20532 MW;  262A2B123EDDBF6B CRC64;
     MISTTIFIIT SLAAVTYGRS HLTVPVGSTC TLQGPQEGYV TWWRIYDNGG FARPCDQPGT
     KFSCNGRDLT IINITSNEQG FYYGTNYKNS LDYNIIVVPA TTSAPRKSTF SSSSAKASTI
     PKTASAMLKL PKIALSNSTA APNTIPKSTI GIITAVVVGL MIIFLCIMYY ACCYRKHEQK
     GDALLNFDI