ID   E413_ADE12              Reviewed;         120 AA.
AC   P36709;
DT   01-JUN-1994, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-1994, sequence version 1.
DT   23-FEB-2022, entry version 65.
DE   RecName: Full=Probable early E4 13 kDa protein;
OS   Human adenovirus A serotype 12 (HAdV-12) (Human adenovirus 12).
OC   Viruses; Varidnaviria; Bamfordvirae; Preplasmiviricota; Tectiliviricetes;
OC   Rowavirales; Adenoviridae; Mastadenovirus; Human mastadenovirus A.
OX   NCBI_TaxID=28282;
OH   NCBI_TaxID=9606; Homo sapiens (Human).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=8254750; DOI=10.1128/jvi.68.1.379-389.1994;
RA   Sprengel J., Schmitz B., Heuss-Neitzel D., Zock C., Doerfler W.;
RT   "Nucleotide sequence of human adenovirus type 12 DNA: comparative
RT   functional analysis.";
RL   J. Virol. 68:379-389(1994).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=2349112; DOI=10.1093/nar/18.10.3065;
RA   Hogenkamp T., Esche H.;
RT   "Nucleotide sequence of the right 10% of adenovirus type 12 DNA encoding
RT   the entire region E4.";
RL   Nucleic Acids Res. 18:3065-3066(1990).
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; X73487; CAA51902.1; -; Genomic_DNA.
DR   EMBL; X51800; CAB57853.1; -; Genomic_DNA.
DR   PIR; S10865; S10865.
DR   RefSeq; NP_040935.1; NC_001460.1.
DR   DIP; DIP-41950N; -.
DR   IntAct; P36709; 2.
DR   MINT; P36709; -.
DR   DNASU; 1460865; -.
DR   GeneID; 1460865; -.
DR   Proteomes; UP000004993; Genome.
DR   GO; GO:0039593; P:suppression by virus of host exit from mitosis; IEA:UniProtKB-KW.
DR   InterPro; IPR008680; M_adenovirusE4.
DR   Pfam; PF05385; Adeno_E4; 1.
PE   4: Predicted;
KW   Early protein; Host-virus interaction;
KW   Inhibition of host mitotic exit by virus;
KW   Modulation of host cell cycle by virus.
FT   CHAIN           1..120
FT                   /note="Probable early E4 13 kDa protein"
FT                   /id="PRO_0000221774"
SQ   SEQUENCE   120 AA;  13600 MW;  2004EA4A61B792AF CRC64;
     MPLPCIPPPP VSRDTAACIA WLGLAHASCV DTLRFIKHHD LKITPEAEYI LASLREWLYF
     AFLTERQRCK QKGRGAITSG RTWFCFFKYE DARKSVVYDA ARQTVSLQIG TIQQVPTTAL