ADN1_SCHPO
ID ADN1_SCHPO Reviewed; 391 AA.
AC O74364;
DT 23-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1998, sequence version 1.
DT 03-AUG-2022, entry version 101.
DE RecName: Full=Adhesion defective protein 1;
GN Name=adn1; ORFNames=SPBC30B4.03c;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
RN [2]
RP FUNCTION.
RX PubMed=19542312; DOI=10.1128/ec.00078-09;
RA Dodgson J., Avula H., Hoe K.L., Kim D.U., Park H.O., Hayles J.,
RA Armstrong J.;
RT "Functional genomics of adhesion, invasion, and mycelial formation in
RT Schizosaccharomyces pombe.";
RL Eukaryot. Cell 8:1298-1306(2009).
CC -!- FUNCTION: Probable transcriptional regulator involved in cell adhesion.
CC {ECO:0000269|PubMed:19542312}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the adn1/SEU family. {ECO:0000305}.
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DR EMBL; CU329671; CAA20316.1; -; Genomic_DNA.
DR PIR; T40169; T40169.
DR RefSeq; NP_595528.1; NM_001021438.2.
DR AlphaFoldDB; O74364; -.
DR SMR; O74364; -.
DR BioGRID; 276865; 17.
DR STRING; 4896.SPBC30B4.03c.1; -.
DR iPTMnet; O74364; -.
DR MaxQB; O74364; -.
DR PaxDb; O74364; -.
DR PRIDE; O74364; -.
DR EnsemblFungi; SPBC30B4.03c.1; SPBC30B4.03c.1:pep; SPBC30B4.03c.
DR GeneID; 2540335; -.
DR KEGG; spo:SPBC30B4.03c; -.
DR PomBase; SPBC30B4.03c; adn1.
DR VEuPathDB; FungiDB:SPBC30B4.03c; -.
DR eggNOG; ENOG502QTWZ; Eukaryota.
DR HOGENOM; CLU_706286_0_0_1; -.
DR InParanoid; O74364; -.
DR OMA; PSHAMRE; -.
DR PhylomeDB; O74364; -.
DR PRO; PR:O74364; -.
DR Proteomes; UP000002485; Chromosome II.
DR GO; GO:0005737; C:cytoplasm; ISO:PomBase.
DR GO; GO:0005634; C:nucleus; ISO:PomBase.
DR GO; GO:0005667; C:transcription regulator complex; IBA:GO_Central.
DR GO; GO:0003712; F:transcription coregulator activity; ISO:PomBase.
DR GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR GO; GO:0000122; P:negative regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR GO; GO:0045944; P:positive regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR InterPro; IPR029005; LIM-bd/SEUSS.
DR PANTHER; PTHR10378; PTHR10378; 1.
DR Pfam; PF01803; LIM_bind; 1.
PE 3: Inferred from homology;
KW Cell adhesion; Nucleus; Reference proteome; Transcription;
KW Transcription regulation.
FT CHAIN 1..391
FT /note="Adhesion defective protein 1"
FT /id="PRO_0000350969"
FT REGION 180..217
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 366..391
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 180..216
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 391 AA; 43837 MW; F291CB2F1A3FD49C CRC64;
MVANYASMMY HNGSNILGYG VLRLLQYNEQ LMSGWESTMK DDIGYWRRFV HDFYTEKGTF
RYNIDYKDSP NQEPKLFELS YAALPRFLYL SYCGKLKKMS FLLGNTKEFA IPNNGYFVES
SRASILYQYQ GGVQVIVSGH LRAHFFRAPL LKLDSLEFSA VGHSEYLLRE LMTNASLALS
QSRPPQNQIQ HDGVKSEDPS SESVNINSSS SLLPDSPVNE YGLEPHIMRF MEITETISGM
RDLIAFTLAQ RSGPTSALHK FATALQQQHQ MQKSTSSNIP YANPAPSGFN GSPRNGDVAS
LASNYRYAKQ PPTMPANAIS QANRLLDQNN IPNMDPSILP QSMPIASVPP YSLQGIKRQG
THSPMVEGEN PNNNPNFYSS DMLNAQKRTK V
