ID   E6_GOSHI                Reviewed;         238 AA.
AC   Q01197;
DT   01-APR-1993, integrated into UniProtKB/Swiss-Prot.
DT   01-APR-1993, sequence version 1.
DT   25-MAY-2022, entry version 55.
DE   RecName: Full=Protein E6;
GN   Name=E6;
OS   Gossypium hirsutum (Upland cotton) (Gossypium mexicanum).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Malvales; Malvaceae; Malvoideae; Gossypium.
OX   NCBI_TaxID=3635;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   STRAIN=cv. Coker 312; TISSUE=Fiber;
RX   PubMed=1631059; DOI=10.1073/pnas.89.13.5769;
RA   John M.E., Crow L.J.;
RT   "Gene expression in cotton (Gossypium hirsutum L.) fiber: cloning of the
RT   mRNAs.";
RL   Proc. Natl. Acad. Sci. U.S.A. 89:5769-5773(1992).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA].
RC   STRAIN=cv. Coker 312;
RX   PubMed=8616253; DOI=10.1007/bf00020115;
RA   John M.E.;
RT   "Structural characterization of genes corresponding to cotton fiber mRNA,
RT   E6: reduced E6 protein in transgenic plants by antisense gene.";
RL   Plant Mol. Biol. 30:297-306(1996).
CC   -!- SUBCELLULAR LOCATION: Secreted, cell wall {ECO:0000305}.
CC   -!- TISSUE SPECIFICITY: It is predominantly expressed in fiber cells.
CC   -!- DEVELOPMENTAL STAGE: Concentration of E6 is highest during the late
CC       primary cell wall and early cell wall synthesis stages.
CC   -!- CAUTION: It is uncertain whether Met-1, Met-10 or Met-21 is the
CC       initiator. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAA33056.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; M92051; AAA33055.1; -; mRNA.
DR   EMBL; M92051; AAA33056.1; ALT_INIT; mRNA.
DR   EMBL; U30505; AAB03079.1; -; Genomic_DNA.
DR   PIR; A46130; A46130.
DR   AlphaFoldDB; Q01197; -.
DR   Proteomes; UP000189702; Genome assembly.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR   GO; GO:0090378; P:seed trichome elongation; IEP:AgBase.
DR   InterPro; IPR040290; Prot_E6-like.
DR   PANTHER; PTHR35274; PTHR35274; 1.
PE   2: Evidence at transcript level;
KW   Cell wall; Reference proteome; Secreted.
FT   CHAIN           1..238
FT                   /note="Protein E6"
FT                   /id="PRO_0000086886"
FT   REGION          40..64
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          210..238
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   238 AA;  28226 MW;  7162101A9A91A4FB CRC64;
     MASSPKLFSM SILFLFALFS MQIHAREYFS KFPRVNINEK ETTTREQKHE TFVPQTTQKP
     EEQEPRFIPE TQNGYGLYGH ESGSSRPSFT TKETYEPYVT PVRFHPDEPY NSIPESSNNK
     DTYYYNKNAY ESTKQQNLGE AIFTEKGWST KENQNNNYYN GNNGYNNGEK QGMSDTRYLE
     NGKYYYDVKS ENNYYPNRFD NSRGVASRNE FNENRYNNMG RYHQNQEEFE ESEEEFEP