EAAC_ARATH
ID EAAC_ARATH Reviewed; 381 AA.
AC O65023; Q0WNR4;
DT 15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT 03-MAY-2011, sequence version 2.
DT 03-AUG-2022, entry version 137.
DE RecName: Full=Probable envelope ADP,ATP carrier protein, chloroplastic;
DE AltName: Full=Envelope ADP/ATP translocase;
DE Flags: Precursor;
GN Name=EAAC; OrderedLocusNames=At3g51870; ORFNames=ATEM1.12;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10645728; DOI=10.1023/a:1006395324818;
RA Comella P., Wu H.-J., Laudie M., Berger C., Cooke R., Delseny M.,
RA Grellet F.;
RT "Fine sequence analysis of 60 kb around the Arabidopsis thaliana AtEm1
RT locus on chromosome III.";
RL Plant Mol. Biol. 41:687-700(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP SUBCELLULAR LOCATION.
RA Ruiz Pavon L., Spetea C.;
RL Unpublished observations (NOV-2007).
RN [5]
RP GENE FAMILY.
RX PubMed=15003237; DOI=10.1016/j.tplants.2004.01.007;
RA Picault N., Hodges M., Palmieri L., Palmieri F.;
RT "The growing family of mitochondrial carriers in Arabidopsis.";
RL Trends Plant Sci. 9:138-146(2004).
CC -!- FUNCTION: Transports adenine nucleotides. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Plastid, chloroplast membrane
CC {ECO:0000269|Ref.4}; Multi-pass membrane protein {ECO:0000269|Ref.4}.
CC -!- SIMILARITY: Belongs to the mitochondrial carrier (TC 2.A.29) family.
CC {ECO:0000305}.
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DR EMBL; AF049236; AAC14414.1; -; Genomic_DNA.
DR EMBL; CP002686; AEE78854.1; -; Genomic_DNA.
DR EMBL; AK229373; BAF01235.1; -; mRNA.
DR PIR; T51158; T51158.
DR RefSeq; NP_190755.2; NM_115046.6.
DR AlphaFoldDB; O65023; -.
DR SMR; O65023; -.
DR STRING; 3702.AT3G51870.1; -.
DR PaxDb; O65023; -.
DR PRIDE; O65023; -.
DR ProteomicsDB; 224709; -.
DR EnsemblPlants; AT3G51870.1; AT3G51870.1; AT3G51870.
DR GeneID; 824350; -.
DR Gramene; AT3G51870.1; AT3G51870.1; AT3G51870.
DR KEGG; ath:AT3G51870; -.
DR Araport; AT3G51870; -.
DR TAIR; locus:2074358; AT3G51870.
DR eggNOG; KOG0752; Eukaryota.
DR HOGENOM; CLU_015166_10_5_1; -.
DR InParanoid; O65023; -.
DR OMA; NTRLAYH; -.
DR OrthoDB; 1253450at2759; -.
DR PRO; PR:O65023; -.
DR Proteomes; UP000006548; Chromosome 3.
DR ExpressionAtlas; O65023; baseline and differential.
DR Genevisible; O65023; AT.
DR GO; GO:0009507; C:chloroplast; HDA:TAIR.
DR GO; GO:0009941; C:chloroplast envelope; HDA:TAIR.
DR GO; GO:0031969; C:chloroplast membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0042651; C:thylakoid membrane; IBA:GO_Central.
DR GO; GO:0005347; F:ATP transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0009624; P:response to nematode; HEP:TAIR.
DR Gene3D; 1.50.40.10; -; 1.
DR InterPro; IPR002067; Mit_carrier.
DR InterPro; IPR018108; Mitochondrial_sb/sol_carrier.
DR InterPro; IPR023395; Mt_carrier_dom_sf.
DR Pfam; PF00153; Mito_carr; 3.
DR PRINTS; PR00926; MITOCARRIER.
DR SUPFAM; SSF103506; SSF103506; 1.
DR PROSITE; PS50920; SOLCAR; 3.
PE 2: Evidence at transcript level;
KW Chloroplast; Membrane; Plastid; Reference proteome; Repeat;
KW Transit peptide; Transmembrane; Transmembrane helix; Transport.
FT TRANSIT 1..26
FT /note="Chloroplast"
FT /evidence="ECO:0000255"
FT CHAIN 27..381
FT /note="Probable envelope ADP,ATP carrier protein,
FT chloroplastic"
FT /id="PRO_0000313085"
FT TRANSMEM 78..98
FT /note="Helical; Name=1"
FT /evidence="ECO:0000250"
FT TRANSMEM 154..179
FT /note="Helical; Name=2"
FT /evidence="ECO:0000250"
FT TRANSMEM 191..211
FT /note="Helical; Name=3"
FT /evidence="ECO:0000250"
FT TRANSMEM 237..257
FT /note="Helical; Name=4"
FT /evidence="ECO:0000255"
FT TRANSMEM 281..301
FT /note="Helical; Name=5"
FT /evidence="ECO:0000255"
FT TRANSMEM 334..360
FT /note="Helical; Name=6"
FT /evidence="ECO:0000250"
FT REPEAT 85..177
FT /note="Solcar 1"
FT REPEAT 185..268
FT /note="Solcar 2"
FT REPEAT 279..359
FT /note="Solcar 3"
FT BINDING 159
FT /ligand="ADP"
FT /ligand_id="ChEBI:CHEBI:456216"
FT /evidence="ECO:0000250|UniProtKB:P02722"
FT BINDING 302
FT /ligand="ADP"
FT /ligand_id="ChEBI:CHEBI:456216"
FT /evidence="ECO:0000250|UniProtKB:P02722"
FT CONFLICT 220
FT /note="G -> R (in Ref. 1; AAC14414)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 381 AA; 41718 MW; E4E3A6E03E0C4F69 CRC64;
MEEDRAILTF HRIPSLNSSL ITTSSPAKSG AEQFRRRVLR NPARGDFGLG RFACISLVEK
CEQREFAPTT AQLLNNPLAI LALVPKDAAI FAAGALAGAA AKTVTAPLDR IKLLMQTHGI
RLGQQSAKKA IGFIEAITLI AKEEGVKGYW KGNLPQVIRV LPYSAVQLLA YESYKNLFKG
KDDQLSVIGR LAAGACAGMT STLLTYPLDV LRLRLAVEPG YRTMSQVALS MLRDEGIASF
YYGLGPSLVG IAPYIAVNFC IFDLVKKSLP EEYRKKAQSS LLTAVLSAGI ATLTCYPLDT
VRRQMQMRGT PYKSIPEAFA GIIDRDGLIG LYRGFLPNAL KTLPNSSIRL TTFDMVKRLI
ATSEKQLQKI SDDNRNRDQA Q
