ID   EAEH_ECOLI              Reviewed;         295 AA.
AC   P36943; P77261; Q2MCC4;
DT   01-JUN-1994, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1997, sequence version 2.
DT   25-MAY-2022, entry version 121.
DE   RecName: Full=Putative attaching and effacing protein homolog;
DE   Flags: Precursor;
GN   Name=eaeH; OrderedLocusNames=b0297, JW0291;
OS   Escherichia coli (strain K12).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83333;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RA   Chung E., Allen E., Araujo R., Aparicio A.M., Davis K., Duncan M.,
RA   Federspiel N., Hyman R., Kalman S., Komp C., Kurdi O., Lew H., Lin D.,
RA   Namath A., Oefner P., Roberts D., Schramm S., Davis R.W.;
RT   "Sequence of minutes 4-25 of Escherichia coli.";
RL   Submitted (JAN-1997) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA   Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA   Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA   Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA   Shao Y.;
RT   "The complete genome sequence of Escherichia coli K-12.";
RL   Science 277:1453-1462(1997).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=16738553; DOI=10.1038/msb4100049;
RA   Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA   Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT   "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT   and W3110.";
RL   Mol. Syst. Biol. 2:E1-E5(2006).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 48-295.
RA   Umeda M., Ohtsubo E.;
RL   Submitted (JUL-1992) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the intimin/invasin family. {ECO:0000305}.
CC   -!- CAUTION: Could be the product of a pseudogene. {ECO:0000305}.
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DR   EMBL; U73857; AAB18025.1; -; Genomic_DNA.
DR   EMBL; U00096; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AP009048; BAE76082.1; -; Genomic_DNA.
DR   EMBL; D12594; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   PIR; A64756; A64756.
DR   RefSeq; WP_000020224.1; NZ_CP011343.2.
DR   AlphaFoldDB; P36943; -.
DR   SMR; P36943; -.
DR   BioGRID; 4259795; 126.
DR   IntAct; P36943; 5.
DR   STRING; 316407.85674442; -.
DR   PRIDE; P36943; -.
DR   EnsemblBacteria; BAE76082; BAE76082; BAE76082.
DR   KEGG; ecj:JW0291; -.
DR   PATRIC; fig|83333.103.peg.1056; -.
DR   EchoBASE; EB2080; -.
DR   eggNOG; COG1388; Bacteria.
DR   HOGENOM; CLU_1110106_0_0_6; -.
DR   OMA; YRITLMA; -.
DR   PhylomeDB; P36943; -.
DR   Proteomes; UP000000318; Chromosome.
DR   Proteomes; UP000000625; Chromosome.
DR   GO; GO:0009279; C:cell outer membrane; IBA:GO_Central.
DR   GO; GO:0007155; P:cell adhesion; IEA:InterPro.
DR   Gene3D; 2.40.160.160; -; 1.
DR   InterPro; IPR024519; IAT_beta.
DR   InterPro; IPR038177; IAT_beta_sf.
DR   InterPro; IPR003535; Intimin/invasin_bac.
DR   Pfam; PF11924; IAT_beta; 1.
DR   PRINTS; PR01369; INTIMIN.
PE   5: Uncertain;
KW   Reference proteome; Signal.
FT   SIGNAL          1..25
FT                   /evidence="ECO:0000255"
FT   CHAIN           26..295
FT                   /note="Putative attaching and effacing protein homolog"
FT                   /id="PRO_0000016468"
FT   CONFLICT        48..50
FT                   /note="QHA -> SMR (in Ref. 4)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        292..295
FT                   /note="LTQQ -> KVLGSLSTLLACQHIHIPYQQKFQP (in Ref. 4)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   295 AA;  33175 MW;  93DAD573CCCB2F45 CRC64;
     MSHYKTGHKQ PRFRYSVLAR CVAWANISVQ VLFPLAVTFT PVMAARAQHA VQPRLSMGNT
     TVTADNNVEK NVASFAANAG TFLSSQPDSD ATRNFITGMA TAKANQEIQE WLGKYGTARV
     KLNVDKDFSL KDSSLEMLYP IYDTPTNMLF TQGAIHRTDD RTQSNIGFGW RHFSGNDWMA
     GVNTFIDHDL SRSHTRIGVG AEYWRDYLKL SANGYIRASG WKKSPDIEDY QERPANGWDI
     RAEGYLPAWP QLGASLMYEQ YYGDEVGLFG KDKRQKDPHA ISAEVTYTPV PLTQQ