ADP1_MYCGL
ID ADP1_MYCGL Reviewed; 1122 AA.
AC Q49379; Q49437; Q53351;
DT 15-DEC-1998, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1996, sequence version 1.
DT 03-AUG-2022, entry version 63.
DE RecName: Full=Adhesin P1;
DE AltName: Full=Attachment protein;
DE AltName: Full=Cytadhesin P1;
DE Flags: Precursor;
GN Name=gapA; Synonyms=mgc1;
OS Mycoplasma gallisepticum (Mycoplasmoides gallisepticum).
OC Bacteria; Tenericutes; Mollicutes; Mycoplasmataceae; Mycoplasma.
OX NCBI_TaxID=2096;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=S6;
RX PubMed=8613358; DOI=10.1128/iai.64.5.1541-1547.1996;
RA Keeler C.L. Jr., Hnatow L.L., Whetzel P.L., Dohms J.E.;
RT "Cloning and characterization of a putative cytadhesin gene (mgc1) from
RT Mycoplasma gallisepticum.";
RL Infect. Immun. 64:1541-1547(1996).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-12.
RC STRAIN=S6;
RA Hnatow L.L., Keeler C.L. Jr., Tessmer L., Dohms J.E.;
RL Submitted (OCT-1995) to the EMBL/GenBank/DDBJ databases.
RN [3]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 378-570.
RC STRAIN=S6;
RX PubMed=8363503; DOI=10.2307/1591662;
RA Dohms J.E., Hnatow L.L., Whetzel P., Morgan R., Keeler C.L. Jr.;
RT "Identification of the putative cytadhesin gene of Mycoplasma gallisepticum
RT and its use as a DNA probe.";
RL Avian Dis. 37:380-388(1993).
RN [4]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 159-1122.
RC STRAIN=S6;
RA Goh M.S., Geary S.J.;
RL Submitted (FEB-1996) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Could be involved in cytadherence.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Single-pass type I
CC membrane protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the adhesin P1 family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAC83385.1; Type=Frameshift; Evidence={ECO:0000305};
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DR EMBL; U34842; AAB02987.1; -; Genomic_DNA.
DR EMBL; U44804; AAC83385.1; ALT_FRAME; Genomic_DNA.
DR PIR; T18346; T18346.
DR AlphaFoldDB; Q49379; -.
DR SMR; Q49379; -.
DR STRING; 1006581.GCW_01045; -.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0020035; P:adhesion of symbiont to microvasculature; IEA:UniProtKB-KW.
DR InterPro; IPR022400; Adhesin_P1.
DR InterPro; IPR022116; P1_N.
DR Pfam; PF12378; CytadhesinP1; 1.
DR TIGRFAMs; TIGR03839; termin_org_P1; 1.
PE 3: Inferred from homology;
KW Cell membrane; Cytadherence; Membrane; Signal; Transmembrane;
KW Transmembrane helix.
FT SIGNAL 1..30
FT /evidence="ECO:0000255"
FT CHAIN 31..1122
FT /note="Adhesin P1"
FT /id="PRO_0000020627"
FT TRANSMEM 997..1021
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REGION 183..209
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 244..273
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 544..563
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1066..1122
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1066..1081
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1099..1113
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 313..314
FT /note="DM -> IW (in Ref. 4; AAC83385)"
FT /evidence="ECO:0000305"
FT CONFLICT 382
FT /note="Y -> F (in Ref. 3; no nucleotide entry)"
FT /evidence="ECO:0000305"
FT CONFLICT 501
FT /note="I -> T (in Ref. 3; no nucleotide entry)"
FT /evidence="ECO:0000305"
FT CONFLICT 568
FT /note="R -> G (in Ref. 3; no nucleotide entry)"
FT /evidence="ECO:0000305"
FT CONFLICT 570
FT /note="T -> A (in Ref. 3; no nucleotide entry)"
FT /evidence="ECO:0000305"
FT CONFLICT 693..695
FT /note="DIL -> VYT (in Ref. 4; AAC83385)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 1122 AA; 121306 MW; 155C34DA2D6C3C65 CRC64;
MKKLIFKLSV GITPLALIGL GSFGLAVSGA KPNNLKPVNQ VGEMNSQGQS NLLEKARRWR
NSNFTSLSID GTNPGALVLT GSKSISRIDL YGNVIWTFDP GNTNDLTGKV GFYDANNKLT
AFSGDVSFNV SDLSSKTVVE ATQDQEDPNV FYLLLMPDAA VQQEQKTKDQ VFENYFMSDA
PAAGDTSAEG SATPAGGGSG SSAAGGGAVA PAAASSTARL VEEGNSAGMG TMTPTASTSE
TVIDYNSDQN KIPKPKTLLD SSESSESING GRTYANINTQ KNLQGVIVKV NENLFNSENP
FAVENMAFIK PKDMVDNYPS TWTQGSANGK MTNVLQFYKH DNPNAVNNRF YRAKYYPKRL
ETQTTTPLID SSFSPYEHPE WYEGNQFVMP WMQYITNLGG LYAKDGMVYL FGGNGTWVNN
ESALSIGVFR TKFENRTAEA PGNTKTVGYP YGILLSAISF DATRNGLALA APALGQDVGY
HFVPRLAVGG VSSPRGANGN IFLGSAITWG TNGGNFLDTK WHSPAVIEDA PTTFITVNSS
GVLQNSGSQQ STSTPMPNSN GNESIPYRWT NSYDYNSVRF AALISKPAGG NTKQVESLFT
TALKLDTLNS LPNKFTQENN IFFSYAMLDG RQWSLGTRKD STWLTTNTIN NFTYNTQQQL
ASTAAGENAN PRNILNALTT AKGFDRRDIG NVDILYSNNT NKFTYYYQVG GAITTWPEVQ
VNYKTSANIT YYNLTRTDFG STTPATQDAN TVSSKLNGAY LSSTGDQQGW YNGSIYVKKA
SFTPSSQGYT WQDFKGLTTT ASNAVISNWT KAGYSIRPDD DTVFSVSKIP FEKEITAAVN
VRSLDSYYVQ LNGETSVNTV ARVSPDSSAL TLNPKRITNP LMNRDNVIGQ GAFISRNDIP
SSFFENKIND IVTTEADGTE VLDSKYINSI YRYTPPQNNP HIRLRLLVID RSRATNDFIK
LLPQVLVDGE YVAVPQANSV FVSDQEFTGF DALPGYVLPV AISIPIIIIA LALALGLGIG
IPMSQNRKML KQGFAISNKK VDILTTAVGS VFKQIINRTS VTNIKKTPQM LQANKKDGAS
SPSKPSAPAA KKPTGPTKPS APGAKPTAPA KPKAPAPTKK IE
