ID   ADP2_MYCGA              Reviewed;        1122 AA.
AC   Q9REM8;
DT   15-AUG-2003, integrated into UniProtKB/Swiss-Prot.
DT   15-AUG-2003, sequence version 2.
DT   03-AUG-2022, entry version 87.
DE   RecName: Full=Adhesin P1;
DE   AltName: Full=Adherence protein A;
DE   AltName: Full=Attachment protein;
DE   AltName: Full=Cytadhesin P1;
DE   Flags: Precursor;
GN   Name=gapA; OrderedLocusNames=MYCGA1800; ORFNames=MGA_0934;
OS   Mycoplasma gallisepticum (strain R(low / passage 15 / clone 2))
OS   (Mycoplasmoides gallisepticum).
OC   Bacteria; Tenericutes; Mollicutes; Mycoplasmataceae; Mycoplasma.
OX   NCBI_TaxID=710127;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=R(low / passage 15 / clone 2);
RX   PubMed=12949158; DOI=10.1099/mic.0.26427-0;
RA   Papazisi L., Gorton T.S., Kutish G., Markham P.F., Browning G.F.,
RA   Nguyen D.K., Swartzell S., Madan A., Mahairas G., Geary S.J.;
RT   "The complete genome sequence of the avian pathogen Mycoplasma
RT   gallisepticum strain R(low).";
RL   Microbiology 149:2307-2316(2003).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 94-1122.
RC   STRAIN=R(low);
RX   PubMed=11083776; DOI=10.1128/iai.68.12.6643-6649.2000;
RA   Papazisi L., Troy K.E., Gorton T.S., Liao X., Geary S.J.;
RT   "Analysis of cytadherence-deficient, GapA-negative Mycoplasma gallisepticum
RT   strain R.";
RL   Infect. Immun. 68:6643-6649(2000).
CC   -!- FUNCTION: Could be involved in cytadherence. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Single-pass type I
CC       membrane protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the adhesin P1 family. {ECO:0000305}.
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DR   EMBL; AE015450; AAP56530.2; -; Genomic_DNA.
DR   EMBL; AF214004; AAF25381.1; -; Genomic_DNA.
DR   RefSeq; WP_011113412.1; NC_004829.2.
DR   AlphaFoldDB; Q9REM8; -.
DR   SMR; Q9REM8; -.
DR   KEGG; mga:MGA_0934; -.
DR   PATRIC; fig|233150.7.peg.197; -.
DR   HOGENOM; CLU_279639_0_0_14; -.
DR   OMA; VENMAFI; -.
DR   OrthoDB; 1540677at2; -.
DR   Proteomes; UP000001418; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0020035; P:adhesion of symbiont to microvasculature; IEA:UniProtKB-KW.
DR   InterPro; IPR022400; Adhesin_P1.
DR   InterPro; IPR022116; P1_N.
DR   Pfam; PF12378; CytadhesinP1; 1.
DR   TIGRFAMs; TIGR03839; termin_org_P1; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Cytadherence; Membrane; Reference proteome; Signal;
KW   Transmembrane; Transmembrane helix.
FT   SIGNAL          1..26
FT                   /evidence="ECO:0000255"
FT   CHAIN           27..1122
FT                   /note="Adhesin P1"
FT                   /id="PRO_0000020630"
FT   TRANSMEM        1001..1021
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          182..208
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          244..273
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          541..562
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1066..1122
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        182..200
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1066..1081
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1099..1113
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CONFLICT        337
FT                   /note="F -> C (in Ref. 2; AAF25381)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        645
FT                   /note="T -> A (in Ref. 2; AAF25381)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        826
FT                   /note="V -> A (in Ref. 2; AAF25381)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   1122 AA;  121388 MW;  E57D27A7FBD360AD CRC64;
     MKKLIFKLSV GITPLALIGL GSFGLAVSGA KPNNLKPVNQ VGEMNSQGQS NLLEKARRWR
     NSNFTSLSID GTNPGALVLT GSKSISRIDL YGNVIWTFDP GNTNDLTGKV GFYDANNRLT
     AFSGDVPFNV SDLSSKTVVE ATQDQEDPNV FYLLLIPDAA VQQEQKTKDQ VFENYFMSDA
     PATGDTSAEG SATPAGGGSS SSAAGGGAVA PAAASSTARL VEEGNSAGMG TMTPTASTSE
     TVIDYNSDQN KIPKPKTLLD SSESSESING GRTYANINTQ NNLQGVIVKV NENLFNSENP
     FAVENMAFIK PKDMVDNYPS TWTQGSANGK MTNVLQFYKH DNPNAVNNRF YRAKYYPKRL
     ETQTTTPLID SSFSPYEHPE WYEDNQFVMP WMQYITNLGG LYAKDGMVYL FGGNGTWVNN
     ESALSIGVFR TKFENRTAEA PGNTKTVGYP YGILLSAISF DATRNGLALA PASLGQDVGY
     HFVPRLAVGG VSSPRGANGN IFLGSAITWG TNGGNFLDTK WHSPAVIEDA PTTFVTVNSS
     GALQNSGNPQ PTSTPMPNSN GNESIPYRWT NSYDYNSVRF AALISKPAGG NTKQVESLFT
     TALKLDTLNS LPNKFTQENN IFFSYAMLDG RQWSLGTRKD SAWLTTNTIN NFTYNTQQQL
     ASTVAGENAN PRNILNALTT AKGFDRRDIG NVVYTYSNNT NKFTYYYQVG GAITTWPEVQ
     VNYKTSANIT YYNLTRTDFG STTPATQDAN TVSSKLNGAY LSSTGDQQGW YNGSIYVKKA
     SFTPSSQGYT WQDFKGLTTT ASNAVISNWT KAGYSIRPDD DTVFNVSKIP FEKEITAAVN
     VRSLDSYYVQ LNGETSVNTV ARVSPDSSAL ALNPNRITNP LMNRDNVIGQ GAFISRNDIP
     SSFFENKIND IVTTEADGKE VLDSKYINSI YRYTPPQNNP DIRLRLLVID RSRATNDFIK
     LLPQVLVDGE YVAVPQANSV FVSDQEFTGF DALPGYVLPV AISIPIIIIA LALALGLGIG
     IPMSQNRKML KQGFAISNKK VDILTTAVGS VFKQIINRTS VTNIKKTPQM LQANKKDGAS
     SPSKPSAPAA KKPAGPTKPS APGAKPTAPA KPKAPAPTKK IE