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EATX_STRAG
ID   EATX_STRAG              Reviewed;          90 AA.
AC   Q936E0;
DT   25-MAR-2003, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 3.
DT   25-MAY-2022, entry version 46.
DE   RecName: Full=Antitoxin epsilon;
OS   Streptococcus agalactiae.
OG   Plasmid pIP501.
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
OC   Streptococcus.
OX   NCBI_TaxID=1311;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RA   Thompson J.K., Collins M.A., Foley S.;
RT   "Lactobacillus helveticus ATCC15009 as a host for native and conjugative
RT   plasmid DNA.";
RL   Submitted (AUG-2001) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Antitoxin component of a type II toxin-antitoxin (TA) system.
CC       Neutralizes the toxic effect of cognate zeta toxin. Part of a
CC       postsegregational killing (PSK) system involved in the killing of
CC       plasmid-free cells. Continuous synthesis of the epsilon antitoxin is
CC       required to counteract the zeta toxin (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: In the presence of the zeta toxin, forms an inactive
CC       PezA(2)PezT(2) heterotetramer. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the epsilon antitoxin family. {ECO:0000305}.
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DR   EMBL; AJ301605; CAC70736.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q936E0; -.
DR   SMR; Q936E0; -.
DR   GO; GO:0015643; F:toxic substance binding; IEA:InterPro.
DR   GO; GO:0031342; P:negative regulation of cell killing; IEA:InterPro.
DR   GO; GO:0009636; P:response to toxic substance; IEA:InterPro.
DR   Gene3D; 1.10.8.130; -; 1.
DR   InterPro; IPR035569; Antitoxin_epsilon/PezA_dom_sf.
DR   InterPro; IPR015090; Epsilon_antitox.
DR   Pfam; PF08998; Epsilon_antitox; 1.
DR   SUPFAM; SSF81710; SSF81710; 1.
PE   3: Inferred from homology;
KW   Plasmid; Toxin-antitoxin system.
FT   INIT_MET        1
FT                   /note="Removed"
FT                   /evidence="ECO:0000250"
FT   CHAIN           2..90
FT                   /note="Antitoxin epsilon"
FT                   /id="PRO_0000221549"
SQ   SEQUENCE   90 AA;  10778 MW;  F37646DEBFD81D41 CRC64;
     MAVTYEKTFE IEIINELSES VYNRVLNYVL NHELDTKNTR LLEVNLLNQL EVAQEVDLFQ
     QPFEELQAIH EYWRSMNQYS KQILTKEKVA
 
 
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