EBHB_STAAE
ID EBHB_STAAE Reviewed; 7031 AA.
AC A6QGY5;
DT 02-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT 21-AUG-2007, sequence version 1.
DT 25-MAY-2022, entry version 77.
DE RecName: Full=Extracellular matrix-binding protein EbhB;
DE AltName: Full=ECM-binding protein homolog B;
DE Flags: Precursor;
GN Name=ebhB; OrderedLocusNames=NWMN_1345;
OS Staphylococcus aureus (strain Newman).
OC Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC Staphylococcus.
OX NCBI_TaxID=426430;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Newman;
RX PubMed=17951380; DOI=10.1128/jb.01000-07;
RA Baba T., Bae T., Schneewind O., Takeuchi F., Hiramatsu K.;
RT "Genome sequence of Staphylococcus aureus strain Newman and comparative
RT analysis of staphylococcal genomes: polymorphism and evolution of two major
RT pathogenicity islands.";
RL J. Bacteriol. 190:300-310(2008).
CC -!- CAUTION: In strains Mu3, Mu50, N315 and Newman, ebh is divided into two
CC ORFs, ebhA and ebhB, which correspond to the C-terminal and N-terminal
CC parts of the full gene, respectively. {ECO:0000305}.
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DR EMBL; AP009351; BAF67617.1; -; Genomic_DNA.
DR SMR; A6QGY5; -.
DR EnsemblBacteria; BAF67617; BAF67617; NWMN_1345.
DR KEGG; sae:NWMN_1345; -.
DR HOGENOM; CLU_000047_2_0_9; -.
DR OMA; NRATKEM; -.
DR Proteomes; UP000006386; Chromosome.
DR InterPro; IPR044024; aRib.
DR InterPro; IPR026361; Ebh_dom.
DR InterPro; IPR020840; Extracell_matrix-bd_GA.
DR InterPro; IPR002988; GA_module.
DR InterPro; IPR009063; Ig/albumin-bd_sf.
DR InterPro; IPR005877; YSIRK_signal_dom.
DR Pfam; PF18938; aRib; 1.
DR Pfam; PF01468; GA; 11.
DR Pfam; PF04650; YSIRK_signal; 1.
DR SMART; SM00844; GA; 32.
DR SUPFAM; SSF46997; SSF46997; 62.
DR TIGRFAMs; TIGR04264; hyperosmo_Ebh; 1.
DR TIGRFAMs; TIGR01168; YSIRK_signal; 1.
PE 3: Inferred from homology;
KW Repeat; Signal.
FT SIGNAL 1..39
FT /evidence="ECO:0000255"
FT CHAIN 40..7031
FT /note="Extracellular matrix-binding protein EbhB"
FT /id="PRO_0000345975"
FT DOMAIN 2524..2580
FT /note="FIVAR 1"
FT DOMAIN 2610..2666
FT /note="FIVAR 2"
FT DOMAIN 2687..2750
FT /note="FIVAR 3"
FT DOMAIN 2780..2836
FT /note="FIVAR 4"
FT DOMAIN 2864..2919
FT /note="FIVAR 5"
FT DOMAIN 2947..3002
FT /note="FIVAR 6"
FT DOMAIN 3030..3085
FT /note="FIVAR 7"
FT DOMAIN 3154..3212
FT /note="FIVAR 8"
FT DOMAIN 3280..3339
FT /note="FIVAR 9"
FT DOMAIN 3407..3465
FT /note="FIVAR 10"
FT DOMAIN 3533..3591
FT /note="FIVAR 11"
FT DOMAIN 3659..3717
FT /note="FIVAR 12"
FT DOMAIN 3785..3843
FT /note="FIVAR 13"
FT DOMAIN 3911..3969
FT /note="FIVAR 14"
FT DOMAIN 4037..4095
FT /note="FIVAR 15"
FT DOMAIN 4163..4221
FT /note="FIVAR 16"
FT DOMAIN 4289..4347
FT /note="FIVAR 17"
FT DOMAIN 4415..4473
FT /note="FIVAR 18"
FT DOMAIN 4541..4599
FT /note="FIVAR 19"
FT DOMAIN 4667..4725
FT /note="FIVAR 20"
FT DOMAIN 4793..4851
FT /note="FIVAR 21"
FT DOMAIN 4919..4977
FT /note="FIVAR 22"
FT DOMAIN 5045..5103
FT /note="FIVAR 23"
FT DOMAIN 5171..5229
FT /note="FIVAR 24"
FT DOMAIN 5297..5355
FT /note="FIVAR 25"
FT DOMAIN 5423..5481
FT /note="FIVAR 26"
FT DOMAIN 5549..5607
FT /note="FIVAR 27"
FT DOMAIN 5675..5733
FT /note="FIVAR 28"
FT DOMAIN 5801..5859
FT /note="FIVAR 29"
FT DOMAIN 5927..5985
FT /note="FIVAR 30"
FT DOMAIN 6053..6111
FT /note="FIVAR 31"
FT DOMAIN 6179..6236
FT /note="FIVAR 32"
FT DOMAIN 6304..6362
FT /note="FIVAR 33"
FT DOMAIN 6430..6488
FT /note="FIVAR 34"
FT DOMAIN 6556..6614
FT /note="FIVAR 35"
FT DOMAIN 6682..6740
FT /note="FIVAR 36"
FT DOMAIN 6818..6866
FT /note="FIVAR 37"
FT DOMAIN 6934..6992
FT /note="FIVAR 38"
FT REGION 41..86
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 99..152
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 250..277
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1342..1373
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2418..2438
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 99..130
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 7031 AA; 752580 MW; DAF814034AADEC20 CRC64;
MNYRDKIQKF SIRKYTVGTF STVIATLVFL GFNTSQAHAA ETNQPASVVK QKQQSNNEQT
ENRESQVQNS QNSQNGQSLS ATHENEQPNI SQANLVDQKV AQSSTTNDEQ PASQNVNTKK
DSATAATTQP DKEQSKHKQN ESQSANKNGN DNRAAHVENH EANVVTASDS SDNGNVQHDR
NELQAFFDAN YHDYRFIDRE NADSGTFNYV KGIFDKINTL LGSNDPINNK DLQLAYKELE
QAVALIRTMP QRQQTSRRSN RIQTRSVESR AAEPRSVSDY QNANSSYYVE NANDGSGYPV
GTYINASSKG APYNLPTTPW NTLKASDSKE IALMTAKQTG DGYQWVIKFN KGHAPHQNMI
FWFALPADQV PVGRTDFVTV NSDGTNVQWS HGAGAGANKP LQQMWEYGVN DPHRSHDFKI
RNRSGQVIYD WPTVHIYSLE DLSRASDYFS EAGATPATKA FGRQNFEYIN GQKPAESPGV
PKVYTFIGQG DASYTISFKT QGPTVNKLYY AAGGRALEYN QLFMYSQLYV ESTQDHQQRL
NGLRQVVNRT YRIGTTKRVE VSQGNVQTKK VLESTNLNID DFVDDPLSYV KTPSNKVLGF
YSNNANTNAF RPGGAQQLNE YQLSQLFTDQ KLQEAARTRN PIRLMIGFDY PDAYGNSETL
VPVNLTVLPE IQHNIKFFKN DDTQNIAEKP FSKQAGHPVF YVYAGNQGNA SVNLGGSVTS
IQPLRINLTS NENFTDKDWQ ITGIPRTLHI ENSTNRPNNA RERNIELVGN LLPGDYFGTI
RFGRKEQLFE IRVKPHTPTI TTTAEQLRGT ALQKVPVNIS GIPLDPSALV YLVAPTNQTT
NGGSEADQIP SGYTILATGT PDGVHNTITI RPQDYVVFIP PVGKQIRAVV YYNKVVASNM
SNAVTILPDD IPPTINNPVG INAKYYRGDE VNFTMGVSDR HSGIKNTTIT TLPNGWTSNL
TKADKNNGSL SITGRVSMNQ AFNSDITFKV SATDNVNNTT NDSQSKHVSI HVGKISEDAH
PIVLGNTEKV VVVNPTAVSN DEKQSIITAF MNKNQNIRGY LASTDPVTVD NNGNVTLHYR
DGSSTTLDAT NVMTYEPVVK PEYQTVNAAK TATVTIAKGQ SFSIGDIKQY FTLSNGQPIP
SGTFTNITSD RTIPTAQEVS QMNAGTQLYH ITATNAYHKD SEDFYISLKI IDVKQPEGDQ
RVYRTSTYDL TTDEISKVKQ AFINANRDVI TLAEGDISVT NTPNGANVST ITVNINKGRL
TKSFASNLAN MNFLRWVNFP QDYTVTWTNA KIANRPTDGG LSWSDDHKSL IYRYDATLGT
QITTNDILTM LKATTTVPGL RNNITGNEKS QAEAGGRPNF RTTGYSQSNA TTDGQRQFTL
NGQVIQVLDI INPSNGYGGQ PVTNSNTRAN HSNSTVVNVN EPAANGAGAF TIDHVVKSNS
THNASDAVYK AQLYLTPYGP KQYVEHLNQN TGNTTDAINI YFVPSDLVNP TISVGNYTNH
QVFSGETFTN TITANDNFGV QSVTVPNTSQ ITGTVDNNHQ HVSATAPNVT SATNKTINLL
ATDTSGNTAT TSFNVTVKPL RDKYRVGTSS TAANPVRIAN ISNNATVSQA DQTTIINSLT
FTETVPNRSY ARASANEITS KTVSNVSRTG NNANVTVTVT YQDGTTSTVT VPVKHVIPEI
VAHSHYTVQG QDFPAGNGSS ASDYFKLSNG SDIADATITW VSGQAPNKDN TRIGEDITVT
AHILIDGETT PITKTATYKV VRTVPKHVFE TARGVLYPGV SDMYDAKQYV KPVNNSWSTN
AQHMNFQFVG TYGPNKDVVG ISTRLIRVTY DNRQTEDLTI LSKVKPDPPR IDANSVTYKA
GLTNQEIKVN NVLNNSSVKL FKADNTPLNV TNITHGSGFS SVVTVSDALP NGGIKAKSSI
SMNNVTYTTQ DEHGQVVTVT RNESVDSNDS ATVTVTPQLQ ATTEGAVFIK GGDGFDFGHV
ERFIQNPPHG ATVAWHDSPD TWKNTVGNTH KTAVVTLPNG QGTRNVEVPV KVYPVANAKA
PSRDVKGQNL TNGTDAMNYI TFDPNTNTNG ITAAWANRQQ PNNQQAGVQH LNVDVTYPGI
SAAKRVPVTV NVYQFEFPQT TYTTTVGGTL ASGTQASGYA HMQNATGLPT DGFTYKWNRD
TTGTNDANWS AMNKPNVAKV VNAKYDVIYN GHTFATSLPA KFVVKDVQPA KPTVTETAAG
AITIAPGANQ TVNTHAGNVT TYADKLVIKR NGNVVTTFTR RNNTSPWVKE ASAATVAGIA
GTNNGITVAA GTFNPADTIQ VVATQGSGET VSDEQRSDDF TVVAPQPNQA TTKIWQNGHI
DITPNNPSGH LINPTQAMDI AYTEKVGNGA EHSKTINVVR GQNNQWTIAN KPDYVTLDAQ
TGKVTFNANT IKPNSSITIT PKAGTGHSVS SNPSTLTAPA AHTVNTTEIV KDYGSNVTAA
EINNAVQVAN KRTATIKNGT AMPTNLAGGS TTTIPVTVTY NDGSTEEVQE SIFTKADKRE
LITAKNHLDD PVSTEGKKPG TITQYNNAMH NAQQQINTAK TEAQQVINNE RATPQQVSDA
LTKVRAAQTK IDQAKALLQN KEDNSQLVTS KNNLQSSVNQ VPSTAGMTQQ SIDNYNAKKR
EAETEITAAQ RVIDNGDATA QQISDEKHRV DNALTALNQA KHDLTADTHA LEQAVQQLNR
TGTTTGKKPA SITAYNNSIR ALQSDLTSAK NSANAIIQKP IRTVQEVQSA LTNVNRVNER
LTQAINQLVP LADNSALKTA KTKLDEEINK SVTTDGMTQS SIQAYENAKR AGQTESTNAQ
NVINNGDATD QQIAAEKTKV EEKYNSLKQA IAGLTPDLAP LQTAKTQLQN DIDQPTSTTG
MTSASIAAFN EKLSAARTKI QEIDRVLASH PDVATIRQNV TAANAAKSAL DQARNGLTVD
KAPLENAKNQ LQHSIDTQTS TTGMTQDSIN AYNAKLTAAR NKIQQINQVL AGSPTVEQIN
TNTSTANQAK SDLDHARQAL TPDKAPLQTA KTQLEQSINQ PTDTTGMTTA SLNAYNQKLQ
AARQKLTEIN QVLNGNPTVQ NINDKVTEAN QAKDQLNTAR QGLTLDRQPA LTTLHGASNL
NQAQQNNFTQ QINAAQNHAA LETIKSNITA LNTAMTKLKD SVADNNTIKS DQNYTDATPA
NKQAYDNAVN AAKGVIGETT NPTMDVNTVN QKAASVKSTK DALDGQQNLQ RAKTEATNAI
THASDLNQAQ KNALTQQVNS AQNVQAVNDI KQTTQSLNTA MTGLKRGVAN HNQVVQSDNY
VNADTNKKND YNNAYNHAND IINGNAQHPV ITPSDVNNAL SNVTSKEHAL NGEAKLNAAK
QEANTALGHL NNLNNAQRQN LQSQINGAHQ IDAVNTIKQN ATNLNSAMGN LRQAVADKDQ
VKRTEDYADA DTAKQNAYNS AVSSAETIIN QTTNPTMSVD DVNRATSAVT SNKNALNGYE
KLAQSKTDAA RAIDALPHLN NAQKADVKSK INAASNIAGV NTVKQQGTDL NTAMGNLQGA
INDEQTTLNS QNYQDATPSK KTAYTNAVQA AKDILNKSNG QNKTKDQVTE AMNQVNSAKN
NLDGTRLLDQ AKQTAKQQLN NMTHLTTAQK TNLTNQINSG TTVAGVQTVQ SNANTLDQAM
NTLRQSIANK DATKASEDYV DANNDKQTAY NNAVAAAETI INANSNPEMN PSTITQKAEQ
VNSSKTALNG DENLAAAKQN AKTYLNTLTS ITDAQKNNLI SQITSATRVS GVDTVKQNAQ
HLDQAMASLQ NGINNESQVK SSEKYRDADT NKQQEYDNAI TAAKAILNKS TGPNTAQNAV
EAALQRVNNA KDALNGDAKL IAAQNAAKQH LGTLTHITTA QRNDLTNQIS QATNLAGVES
VKQNANSLDG AMGNLQTAIN DKSGTLASQN FLDADEQKRN AYNQAVSAAE TILNKQTGPN
TAKTAVEQAL NNVNNAKHAL NGTQNLNNAK QAAITAINGA SDLNQKQKDA LKAQANGAQR
VSNAQDVQHN ATELNTAMGT LKHAIADKTN TLASSKYVNA DSTKQNAYTT KVTNAEHIIS
GTPTVVTTPS EVTAAANQVN SAKQELNGDE RLREAKQNAN TAIDALTQLN TPQKAKLKEQ
VGQANRLEDV QTVQTNGQAL NNAMKGLRDS IANETTVKTS QNYTDASPNN QSTYNSAVSN
AKGIINQTNN PTMDTSAITQ ATTQVNNAKN GLNGAENLRN AQNTAKQNLN TLSHLTNNQK
SAISSQIDRA GHVSEVTATK NAATELNTQM GNLEQAIHDQ NTVKQSVKFT DADKAKRDAY
TNAVSRAEAI LNKTQGANTS KQDVEAAIQN VSSAKNALNG DQNVTNAKNA AKNALNNLTS
INNAQKRDLT TKIDQATTVA GVEAVSNTST QLNTAMANLQ NGINDKTNTL ASENYHDADS
DKKTAYTQAV TNAENILNKN SGSNLDKTAV ENALSQVANA KGALNGNHNL EQAKSNANTT
INGLQHLTTA QKDKLKQQVQ QAQNVAGVDT VKSSANTLNG AMGTLRNSIQ DNTATKNGQN
YLDATERNKT NYNNAVDSAN GVINATSNPN MDANAINQIA TQVTSTKNAL DGTHNLTQAK
QTATNAIDGA TNLNKAQKDA LKAQVTSAQR VANVTSIQQT ANELNTAMGQ LQHGIDDENA
TKQTQKYRDA EQSKKTAYDQ AVAAAKAILN KQTGSNSDKA AVDRALQQVT STKDALNGDA
KLAEAKAAAK QNLGTLNHIT NAQRTDLEGQ INQATTVDGV NTVKTNANTL DGAMNSLQGS
INDKDATLRN QNYLDADESK RNAYTQAVTA AEGILNKQTG GNTSKADVDN ALNAVTRAKA
ALNGADNLRN AKTSATNTID GLPNLTQLQK DNLKHQVEQA QNVAGVNGVK DKGNTLNTAM
GALRTSIQND NTTKTSQNYL DASDSNKNNY NTAVNNANGV INATNNPNMD ANAINGMANQ
VNTTKAALNG AQNLAQAKTN ATNTINNAHD LNQKQKDALK TQVNNAQRVS DANNVQHTAT
ELNSAMTALK AAIADKERTK ASGNYVNADQ EKRQAYDSKV TNAENIISGT PNATLTVNDV
NSAASQVNAA KTALNGDNNL RVAKEHANNT IDGLAQLNNA QKAKLKEQVQ SATTLDGVQT
VKNSSQTLNT AMKGLRDSIA NEATIKAGQN YTDASPNNRN EYDSAVTAAK AIINQTSNPT
MEPNTITQVT SQVTTKEQAL NGARNLAQAK TTAKNNLNNL TSINNAQKDA LTRSIDGATT
VAGVNQETAK ATELNNAMHS LQNGINDETQ TKQTQKYLDA EPSKKSAYDQ AVNAAKAILT
KASGQNVDKA AVEQALQNVN STKTALNGDA KLNEAKAAAK QTLGTLTHIN NAQRTALDNE
ITQATNVEGV NTVKAKAQQL DGAMGQLETS IRDKDTTLQS QNYQDADDAK RTAYSQAVNA
AATILNKTAG GNTPKADVER AMQAVTQANT ALNGIQNLDR AKQAANTAIT NASDLNTKQK
EALKAQVTSA GRVSAANGVE HTATELNTAM TALKRAIADK AETKASGNYV NADANKRQAY
DEKVTAAENI VSGTPTPTLT PADVTNAATQ VTNAKTQLNG NHNLEVAKQN ANTAIDGLTS
LNGPQKAKLK EQVGQATTLP NVQTVRDNAQ TLNTAMKGLR DSIANEATIK AGQNYTDASQ
NKQTDYNSAV TAAKAIIGQT TSPSMNAQEI NQAKDQVTAK QQALNGQENL RTAQTNAKQH
LNGLSDLTDA QKDAVKRQIE GATHVNEVTQ AQNNADALNT AMTNLKNGIQ DQNTIKQGVN
FTDADEAKRN AYTNAVTQAE QILNKAQGPN TSKDGVETAL ENVQRAKNEL NGNQNVANAK
TTAKNALNNL TSINNAQKEA LKSQIEGATT VAGVNQVSTT ASELNTAMSN LQNGINDEAA
TKAAQKYTDA DREKQTAYND AVTAAKTLLD KTAGSNDNKA AVEQALQRVN TAKTALNGDE
RLNEAKNTAK QQVATMSHLT DAQKANLTSQ IESGTTVAGV QGIQANAGTL DQAMNQLRQS
IASKDATKSS EDYQDANADL QNAYNDAVTN AEGIISATNN PEMNPDTINQ KASQVNSAKS
ALNGDEKLAA AKQTAKSDIG RLTDLNNAQR TAANAEVDQA PNLAAVTAAK NKATSLNTAM
GNLKHALAEK DNTKRSVNYT DADQPKQQAY DTAVTQAEAI TNANGSNANE TQVQAALNQL
NQAKNDLNGD NKVAQAKESA KRALASYSNL NNAQSTAATS QIDNATTVAG VTAAQNTANE
LNTAMGQLQN GINDQNTVKQ QVNFTDADQG KKDAYTNAVT NAQGILDKAH GQNMTKAQVE
AALNQVTTAK NALNGDANVR QAKSDAKANL GTLTHLNNAQ KQDLTSQIEG ATTVNGVNGV
KTKAQDLDGA MQRLQSAIAN KDQTKASENY IDADPTKKTA FDNAITQAES YLNKDHGANK
DKQAVEQAIQ SVTSTENALN GDANLQRAKT EAIQAIDNLT HLNTPQKTAL KQQVNAAQRV
SGVTDLKNSA TSLNNAMDQL KQAIADHDTI VASGNYTNAS PDKQGAYTDA YNAAKNIVNG
SPNVITNAAD VTAATQRVNN AETGLNGDTN LATAKQQAKD ALRQMTHLSD AQKQSITGQI
DSATQVTGVQ SVKDNATNLD NAMNQLRNSI ANKDDVKASQ PYVDADRDKQ NAYNTAVTNA
ENIINATSQP TLDPSAVTQA ANQVSTNKTA LNGAQNLANK KQETTANINQ LSHLNNAQKQ
DLNTQVTNAP NISTVNQVKT KAEQLDQAME RLINGIQDKD QVKQSVNFTD ADPEKQTAYN
NAVTAAENII NQANGTNANQ SQVEAALSTV TTTKQALNGD RKVTDAKNNA NQTLSTLDNL
NNAQKGAVTG NINQAHTVAE VTQAIQTAQE LNTAMGNLKN SLNDKDTTLG SQNFADADPE
KKNAYNEAVH NAENILNKST GTNVPKDQVE AAMNQVNATK AALNGTQNLE KAKQHANTAI
DGLSHLTNAQ K
