EBHB_STAAN
ID EBHB_STAAN Reviewed; 3890 AA.
AC Q7A5M1;
DT 02-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 1.
DT 25-MAY-2022, entry version 94.
DE RecName: Full=Extracellular matrix-binding protein EbhB;
DE AltName: Full=ECM-binding protein homolog B;
DE Flags: Precursor;
GN Name=ebhB; OrderedLocusNames=SA1268;
OS Staphylococcus aureus (strain N315).
OC Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC Staphylococcus.
OX NCBI_TaxID=158879;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=N315;
RX PubMed=11418146; DOI=10.1016/s0140-6736(00)04403-2;
RA Kuroda M., Ohta T., Uchiyama I., Baba T., Yuzawa H., Kobayashi I., Cui L.,
RA Oguchi A., Aoki K., Nagai Y., Lian J.-Q., Ito T., Kanamori M.,
RA Matsumaru H., Maruyama A., Murakami H., Hosoyama A., Mizutani-Ui Y.,
RA Takahashi N.K., Sawano T., Inoue R., Kaito C., Sekimizu K., Hirakawa H.,
RA Kuhara S., Goto S., Yabuzaki J., Kanehisa M., Yamashita A., Oshima K.,
RA Furuya K., Yoshino C., Shiba T., Hattori M., Ogasawara N., Hayashi H.,
RA Hiramatsu K.;
RT "Whole genome sequencing of meticillin-resistant Staphylococcus aureus.";
RL Lancet 357:1225-1240(2001).
CC -!- CAUTION: In strains Mu3, Mu50, N315 and Newman, ebh is divided into two
CC ORFs, ebhA and ebhB, which correspond to the C-terminal and N-terminal
CC parts of the full gene, respectively. {ECO:0000305}.
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DR EMBL; BA000018; BAB42528.1; -; Genomic_DNA.
DR PIR; C89921; C89921.
DR SMR; Q7A5M1; -.
DR EnsemblBacteria; BAB42528; BAB42528; BAB42528.
DR KEGG; sau:SA1268; -.
DR HOGENOM; CLU_000047_2_0_9; -.
DR OMA; LRCDNDS; -.
DR Proteomes; UP000000751; Chromosome.
DR InterPro; IPR044024; aRib.
DR InterPro; IPR026361; Ebh_dom.
DR InterPro; IPR020840; Extracell_matrix-bd_GA.
DR InterPro; IPR002988; GA_module.
DR InterPro; IPR009063; Ig/albumin-bd_sf.
DR InterPro; IPR005877; YSIRK_signal_dom.
DR Pfam; PF18938; aRib; 1.
DR Pfam; PF01468; GA; 2.
DR Pfam; PF04650; YSIRK_signal; 1.
DR SMART; SM00844; GA; 7.
DR SUPFAM; SSF46997; SSF46997; 12.
DR TIGRFAMs; TIGR04264; hyperosmo_Ebh; 1.
DR TIGRFAMs; TIGR01168; YSIRK_signal; 1.
PE 3: Inferred from homology;
KW Repeat; Signal.
FT SIGNAL 1..39
FT /evidence="ECO:0000255"
FT CHAIN 40..3890
FT /note="Extracellular matrix-binding protein EbhB"
FT /id="PRO_0000345979"
FT DOMAIN 2524..2580
FT /note="FIVAR 1"
FT DOMAIN 2610..2666
FT /note="FIVAR 2"
FT DOMAIN 2687..2750
FT /note="FIVAR 3"
FT DOMAIN 2780..2836
FT /note="FIVAR 4"
FT DOMAIN 2864..2919
FT /note="FIVAR 5"
FT DOMAIN 2947..3002
FT /note="FIVAR 6"
FT DOMAIN 3030..3085
FT /note="FIVAR 7"
FT DOMAIN 3154..3212
FT /note="FIVAR 8"
FT DOMAIN 3280..3339
FT /note="FIVAR 9"
FT DOMAIN 3407..3465
FT /note="FIVAR 10"
FT DOMAIN 3533..3591
FT /note="FIVAR 11"
FT DOMAIN 3659..3717
FT /note="FIVAR 12"
FT DOMAIN 3785..3843
FT /note="FIVAR 13"
FT REGION 41..152
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 249..277
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1347..1372
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2418..2438
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 41..125
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 126..141
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 3890 AA; 420628 MW; 593A6FEA79DCE2B7 CRC64;
MNYRDKIQKF SIRKYTVGTF STVIATLVFL GFNTSQAHAA ETNQPASVVK QKQQSNNEQT
ENRESQVQNS QNSQNSQSLS ATHENEQPNN SQANLVNQKV AQSSTTNDEQ PASQNVNTKK
DSATAATTQP DKEESKHKQN ESQSANKNGN DNRAAHVENH EANVVTASDS SDNGNVQHDR
NELQAFFDAN YHDYRFIDRE NADSGTFNYV KGIFDKINTL LGSNDPINNK DLQLAYKELE
QAVALIRTMP QRQQTSRRSN RIQTRSVESR AAEPRSVSDY QNANSSYYVE NANDGSGYPV
GTYINASSKG APYNLPTTPW NTLKASDSKE IALMTAKQTG DGYQWVIKFN KGHAPHQNMI
FWFALPADQV PVGRTDFVTV NSDGTNVQWS HGAGAGANKP LQQMWEYGVN DPDRSHDFKI
RNRSGQVIYS WPTVHVYSLE DLSRASDYFS EAGATPATKA FGRQNFEYIN GQKPAESPGV
PKVYTFIGQG DASYTISFKT QGPTVNKLYY AAGGRALEYN QLFMYSQLYV ESTQDHQQRL
NGLRQVVNRT YRIGTTKRVE VSQGNVQTKK VLESTNLNID DFVDDPLSYV KTPSNKVLGF
YPTNANTNAF RPGGVQELNE YQLSQLFTDQ KLQEAARTRN PIRLMIGFDY PDGYGNSETL
VPVNLTVLPE IQHNIKFFKN DDTQNIAEKP FSKQAGHPVF YVYAGNQGNA SVNLGGSVTS
IQPLRINLTS NENFTDKDWQ ITGIPRTLHI ENSTNRTNNA RERNIELVGN LLPGDYFGTI
RFGRKEQLFE IRVKPHTPTI TTTAEQLRGT ALQKVPVNIS GIPLDPSALV YLVAPTNQTT
NGGSEADQIP SGYTILATGT PDGVHNTITI RPQDYVVFIP PVGKQIRAVV YYNKVVASNM
SNAVTILPDD IPPTINNPVG INAKYYRGDE VNFTMGVSDR HSGIKNTTIT TLPSGWTSNL
TKSDNKNGSL AITGRVSMNQ AFNSDITFKV SATDNVNNTT NDSQSKHVSI HVGKISEDAH
PIVLGNTEKV VVVNPTAVSN DEKQSIITAF MNKNQNIRGY LASTDPVTVD NNGNVTLHYR
DGSSTTLDAT NVMTYEPVVK SEYQTANAAK TATVTIAKGQ SFNIGDIKQY FTLSNGQAIP
NGTFTNITSD RTIPTAQEVS QMNAGTQLYH IVASNAYHKD TEDFYISLKI VDVKQPEGDQ
RVYRTSTYDL TTDEISKVKQ AFINANRDVI TLAEGDISVT NTPNGANVST ITVNINKGRL
TKSFASNLAN MNFLRWVNFP QDYTVTWTNA KIANRPTDGG LSWSDDHKSL IYRYDATLGT
QITTNDILTM LKATTTVPGL RNNITGNEKA QAEAGGRPNY RTTGYSQSNA TTDGQRQFTL
NGQVIQILDI INPSNGYGGQ PVTNSNTRAN HSNSTVVNVN EPAANGAGAF TIDHVVKSNS
THNASDAVYK AQLYLTPYGP KQYVEHLNQN TGNTTDAINI YFVPSDLVNP TISVGNYTNH
QVFSGETFTN TITANDNFGV QSVTVPNTSQ ITGTVDNNHQ HVSATAPNVT SATSKTINLL
ATDTSGNTAT TSFNVTVKPL RDKYRVGTSS TAANPVRIAN ISNNATVSQA DQTTIINSLT
FTSNAPNRNY ATASANEITS KTVSNVSRTG NNANVTVTVT HQDGTTSTVT VPVKHVIPEI
VAHSHYTVQG QDFPAGNGSS AADYFKLSNG SAIPDATITW VSGQAPNKDN TRIGEDITVT
AHILIDGETT PITKTATYKV VRTVPKHVFE TARGVLYPGV SDMYDAKQYV KPVNNSWSTN
AQHMNFQFVG TYGPNKDVVG ISTRLIRVTY DNRQTEDLTI LSKVKPDPPR IDANSVTYKA
GLTNQEIKVN NVLNNSSVKL FKADNTPLNV TNITHGSGFS SVVTVSDALP NGGIKAKSSI
SMNNVTYTTQ DEHGQVVTVT RNESVDSNDS ASVTVTPQLQ ATTEGAVFIK GGDGFDFGHV
ERFIQNPPHG ATVAWHDSPD TWKNTVGNTH KTAVVTLPSG QGTRNVEVPV KVYPVANAKA
PSRDVKGQNL THGTNAIDYI TFDPNTNTNG ITAAWANRQQ PNNQQAGVQH LNVDVTYPGI
SAAKRVPVTV NVYQFEFPQT TYTTTVGGTL ASGTQASGYA HMQNASGLPT DGFTYKWNRD
TTGTNDANWA AMNKPNTAQV VNAKYDVIYN GHTFATSLPA KFVVKDVQPA KPTVTETAAG
AITIAPGANQ TVNTHAGNVT TYADKLVIKR NGNVVTTFTR RNNTSPWVKE ASADNVTGIV
GTNNGITVAA GTFNPADTIQ VVATQGSGET ISDEQRSDDF TVVAPQPNQA TTKIWQNGHI
DITPNNPSGH LINPTQAMDI AYTEKVGNGA EHSKTINVVR GQNNQWTIAN KPDYVTLDAQ
TGKVTFNANT IKPNSSITIT PKAGTGHSVS SNPSTLTAPA AHTVNTTEIV KDYGSNVTAA
EINNAVQVAN KRTATIKNGT AMPTNLAGGS TTTIPVTVTY NDGSTEEVQE SIFTKADKRE
LITAKNHLDD PVSTEGKKPG TITQYNNAMH NAQQQINTAK TEAQQVINNE RATPQQVSDA
LTKVRAAQTK IDQAKALLQN KEDNSQLVTS KNNLQSSVNQ VPSTAGMTQQ SIDNYNAKKR
EAETEITAAQ RVIDNGDATA QQISDEKHRV DNALTALNQA KHDLTADTHA LEQAVQQLNR
TGTTTGKKPA SITAYNNSIR ALQSDLTSAK NSANAIIQKP IRTVQEVQSA LTNVNRVNER
LTQAINQLVP LADNSALRTA KTKLDEEINK SVTTDGMTQS SIQAYENAKR AGQTETTNAQ
NVINNGDATD QQIAAEKTKV EEKYNSLKQA IAGLTPDLAP LQTAKTQLQN DIDQPTSTTG
MTSASVAAFN DKLSAARTKI QEIDRVLASH PDVATIRQNV TAANAAKTAL DQARNGLTVD
KAPLENAKNQ LQHSIDTQTS TTGMTQDSIN AYNAKLTAAR NKVQQINQVL AGSPTVDQIN
TNTSAANQAK SDLDHARQAL TPDKAPLQNA KTQLEQSINQ PTDTTGMTTA SLNAYNQKLQ
AARQKLTEIN QVLNGNPTVQ NINDKVAEAN QAKDQLNTAR QGLTLDRQPA LTTLHGASNL
NQAQQNNFTQ QINAAQNHAA LETIKSNITA LNTAMTKLKD SVADNNTIKS GQNYTDATPA
NKQAYDNAVN AAKGVIGETT NPTMDVNTVN QKAASVKSTK DALDGQQNLQ RAKTEATNAI
THASDLNQAQ KNALTQQVNS AQNVQAVNDI KQTTQSLNTA MTGLKRGVAN HNQVVQSDNY
VNADTNKKND YNNAYNHAND IINGNAQHPV ITPSDVNNAL SNVTSKEHAL NGEAKLNAAK
QEANTALGHL NNLNNVQRQN LQSQINGAHQ IDAVNTIKQN ATNLNSAMGN LRQAVADKDQ
VKRTEDYADA DTAKQNAYNS AVSSAETIIN QTANPTMSVD DVNRATSAVT TNKNALNGDE
KLVQSKTDAA RAIDALPHLN NAQKADVKSK INAASNIAGV NTVKQQGTDL NTAMGNLQGA
INDEQTTLNS QNYQDATPSK KTAYTNAVQA AKDILNKSNG QNKTKDQVTE AMNQVNSAKN
NLDGTRLLDQ AKQTAKQQLN NMTHLTTAQK TNLTNQINSG TTVAGVHTVQ SNANTLDQAM
NTLRQSIANN DATKASEDYV DANNDKQTAY NNAVAAAETI INANSNPEMN PSTITQKAEQ
VNSSKTALNG DENLATAKQN AKTYLNTLTS ITDAQKNNLI SQISSATRVS GVDTVKQNAQ
HLDQAMANLQ NGINNESQVK SSEKYRDADT NKQQEYDNAI TAAKAILNKS TGPNTAQNAV
EAALQRVNTA KDALNGDAKL IAAQNAAKQH LGTLTHITTA QRNDLTNQIS
