EBH_STAA3
ID EBH_STAA3 Reviewed; 10421 AA.
AC Q2FH04;
DT 02-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT 21-MAR-2006, sequence version 1.
DT 03-AUG-2022, entry version 90.
DE RecName: Full=Extracellular matrix-binding protein ebh;
DE AltName: Full=ECM-binding protein homolog;
DE Flags: Precursor;
GN Name=ebh; OrderedLocusNames=SAUSA300_1327;
OS Staphylococcus aureus (strain USA300).
OC Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC Staphylococcus.
OX NCBI_TaxID=367830;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=USA300;
RX PubMed=16517273; DOI=10.1016/s0140-6736(06)68231-7;
RA Diep B.A., Gill S.R., Chang R.F., Phan T.H., Chen J.H., Davidson M.G.,
RA Lin F., Lin J., Carleton H.A., Mongodin E.F., Sensabaugh G.F.,
RA Perdreau-Remington F.;
RT "Complete genome sequence of USA300, an epidemic clone of community-
RT acquired meticillin-resistant Staphylococcus aureus.";
RL Lancet 367:731-739(2006).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Single-pass membrane
CC protein {ECO:0000305}.
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DR EMBL; CP000255; ABD22444.1; -; Genomic_DNA.
DR RefSeq; WP_001109328.1; NZ_CP027476.1.
DR SMR; Q2FH04; -.
DR PRIDE; Q2FH04; -.
DR EnsemblBacteria; ABD22444; ABD22444; SAUSA300_1327.
DR KEGG; saa:SAUSA300_1327; -.
DR HOGENOM; CLU_222673_0_0_9; -.
DR OMA; NRATKEM; -.
DR Proteomes; UP000001939; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR011439; DUF1542.
DR InterPro; IPR026361; Ebh_dom.
DR InterPro; IPR020840; Extracell_matrix-bd_GA.
DR InterPro; IPR002988; GA_module.
DR InterPro; IPR009063; Ig/albumin-bd_sf.
DR InterPro; IPR005877; YSIRK_signal_dom.
DR Pfam; PF07564; DUF1542; 7.
DR Pfam; PF01468; GA; 21.
DR Pfam; PF04650; YSIRK_signal; 1.
DR SMART; SM00844; GA; 52.
DR SUPFAM; SSF46997; SSF46997; 101.
DR TIGRFAMs; TIGR04264; hyperosmo_Ebh; 1.
DR TIGRFAMs; TIGR01168; YSIRK_signal; 1.
PE 3: Inferred from homology;
KW Cell membrane; Membrane; Repeat; Signal; Transmembrane;
KW Transmembrane helix.
FT SIGNAL 1..39
FT /evidence="ECO:0000255"
FT CHAIN 40..10421
FT /note="Extracellular matrix-binding protein ebh"
FT /id="PRO_0000345971"
FT TRANSMEM 10227..10247
FT /note="Helical"
FT /evidence="ECO:0000255"
FT DOMAIN 2524..2580
FT /note="FIVAR 1"
FT DOMAIN 2610..2666
FT /note="FIVAR 2"
FT DOMAIN 2687..2750
FT /note="FIVAR 3"
FT DOMAIN 2780..2836
FT /note="FIVAR 4"
FT DOMAIN 2864..2919
FT /note="FIVAR 5"
FT DOMAIN 2947..3002
FT /note="FIVAR 6"
FT DOMAIN 3030..3085
FT /note="FIVAR 7"
FT DOMAIN 3154..3212
FT /note="FIVAR 8"
FT DOMAIN 3280..3339
FT /note="FIVAR 9"
FT DOMAIN 3407..3465
FT /note="FIVAR 10"
FT DOMAIN 3533..3591
FT /note="FIVAR 11"
FT DOMAIN 3659..3717
FT /note="FIVAR 12"
FT DOMAIN 3785..3843
FT /note="FIVAR 13"
FT DOMAIN 3911..3969
FT /note="FIVAR 14"
FT DOMAIN 4037..4095
FT /note="FIVAR 15"
FT DOMAIN 4163..4221
FT /note="FIVAR 16"
FT DOMAIN 4289..4347
FT /note="FIVAR 17"
FT DOMAIN 4415..4473
FT /note="FIVAR 18"
FT DOMAIN 4541..4599
FT /note="FIVAR 19"
FT DOMAIN 4667..4725
FT /note="FIVAR 20"
FT DOMAIN 4793..4851
FT /note="FIVAR 21"
FT DOMAIN 4919..4977
FT /note="FIVAR 22"
FT DOMAIN 5045..5103
FT /note="FIVAR 23"
FT DOMAIN 5171..5229
FT /note="FIVAR 24"
FT DOMAIN 5297..5355
FT /note="FIVAR 25"
FT DOMAIN 5423..5481
FT /note="FIVAR 26"
FT DOMAIN 5549..5607
FT /note="FIVAR 27"
FT DOMAIN 5675..5733
FT /note="FIVAR 28"
FT DOMAIN 5801..5859
FT /note="FIVAR 29"
FT DOMAIN 5927..5985
FT /note="FIVAR 30"
FT DOMAIN 6053..6111
FT /note="FIVAR 31"
FT DOMAIN 6179..6236
FT /note="FIVAR 32"
FT DOMAIN 6304..6362
FT /note="FIVAR 33"
FT DOMAIN 6430..6488
FT /note="FIVAR 34"
FT DOMAIN 6556..6614
FT /note="FIVAR 35"
FT DOMAIN 6682..6740
FT /note="FIVAR 36"
FT DOMAIN 6818..6866
FT /note="FIVAR 37"
FT DOMAIN 6934..6992
FT /note="FIVAR 38"
FT DOMAIN 7060..7118
FT /note="FIVAR 39"
FT DOMAIN 7186..7244
FT /note="FIVAR 40"
FT DOMAIN 7312..7370
FT /note="FIVAR 41"
FT DOMAIN 7438..7496
FT /note="FIVAR 42"
FT DOMAIN 7564..7622
FT /note="FIVAR 43"
FT DOMAIN 7690..7748
FT /note="FIVAR 44"
FT DOMAIN 7816..7874
FT /note="FIVAR 45"
FT DOMAIN 7942..8000
FT /note="FIVAR 46"
FT DOMAIN 8068..8129
FT /note="FIVAR 47"
FT DOMAIN 8194..8252
FT /note="FIVAR 48"
FT DOMAIN 8320..8378
FT /note="FIVAR 49"
FT DOMAIN 8446..8503
FT /note="FIVAR 50"
FT DOMAIN 8571..8629
FT /note="FIVAR 51"
FT DOMAIN 8697..8755
FT /note="FIVAR 52"
FT DOMAIN 8823..8881
FT /note="FIVAR 53"
FT DOMAIN 8949..9007
FT /note="FIVAR 54"
FT DOMAIN 9075..9129
FT /note="FIVAR 55"
FT DOMAIN 9197..9256
FT /note="FIVAR 56"
FT DOMAIN 9451..9507
FT /note="FIVAR 57"
FT REGION 41..86
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 99..152
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 250..277
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1342..1373
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2418..2438
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 10167..10186
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 10324..10421
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 99..130
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 10324..10402
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 10403..10421
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 10421 AA; 1122579 MW; C52717EC7CF7FE97 CRC64;
MNYRDKIQKF SIRKYTVGTF STVIATLVFL GFNTSQAHAA ETNQPASVVK QKQQSNNEQT
ENRESQVQNS QNSQNGQSLS ATHENEQPNI SQANLVDQKV AQSSTTNDEQ PASQNVNTKK
DSATAATTQP DKEQSKHKQN ESQSANKNGN DNRAAHVENH EANVVTASDS SDNGNVQHDR
NELQAFFDAN YHDYRFIDRE NADSGTFNYV KGIFDKINTL LGSNDPINNK DLQLAYKELE
QAVALIRTMP QRQQTSRRSN RIQTRSVESR AAEPRSVSDY QNANSSYYVE NANDGSGYPV
GTYINASSKG APYNLPTTPW NTLKASDSKE IALMTAKQTG DGYQWVIKFN KGHAPHQNMI
FWFALPADQV PVGRTDFVTV NSDGTNVQWS HGAGAGANKP LQQMWEYGVN DPHRSHDFKI
RNRSGQVIYD WPTVHIYSLE DLSRASDYFS EAGATPATKA FGRQNFEYIN GQKPAESPGV
PKVYTFIGQG DASYTISFKT QGPTVNKLYY AAGGRALEYN QLFMYSQLYV ESTQDHQQRL
NGLRQVVNRT YRIGTTKRVE VSQGNVQTKK VLESTNLNID DFVDDPLSYV KTPSNKVLGF
YSNNANTNAF RPGGAQQLNE YQLSQLFTDQ KLQEAARTRN PIRLMIGFDY PDAYGNSETL
VPVNLTVLPE IQHNIKFFKN DDTQNIAEKP FSKQAGHPVF YVYAGNQGNA SVNLGGSVTS
IQPLRINLTS NENFTDKDWQ ITGIPRTLHI ENSTNRPNNA RERNIELVGN LLPGDYFGTI
RFGRKEQLFE IRVKPHTPTI TTTAEQLRGT ALQKVPVNIS GIPLDPSALV YLVAPTNQTT
NGGSEADQIP SGYTILATGT PDGVHNTITI RPQDYVVFIP PVGKQIRAVV YYNKVVASNM
SNAVTILPDD IPPTINNPVG INAKYYRGDE VNFTMGVSDR HSGIKNTTIT TLPNGWTSNL
TKADKNNGSL SITGRVSMNQ AFNSDITFKV SATDNVNNTT NDSQSKHVSI HVGKISEDAH
PIVLGNTEKV VVVNPTAVSN DEKQSIITAF MNKNQNIRGY LASTDPVTVD NNGNVTLHYR
DGSSTTLDAT NVMTYEPVVK PEYQTVNAAK TATVTIAKGQ SFSIGDIKQY FTLSNGQPIP
SGTFTNITSD RTIPTAQEVS QMNAGTQLYH ITATNAYHKD SEDFYISLKI IDVKQPEGDQ
RVYRTSTYDL TTDEISKVKQ AFINANRDVI TLAEGDISVT NTPNGANVST ITVNINKGRL
TKSFASNLAN MNFLRWVNFP QDYTVTWTNA KIANRPTDGG LSWSDDHKSL IYRYDATLGT
QITTNDILTM LKATTTVPGL RNNITGNEKS QAEAGGRPNF RTTGYSQSNA TTDGQRQFTL
NGQVIQVLDI INPSNGYGGQ PVTNSNTRAN HSNSTVVNVN EPAANGAGAF TIDHVVKSNS
THNASDAVYK AQLYLTPYGP KQYVEHLNQN TGNTTDAINI YFVPSDLVNP TISVGNYTNH
QVFSGETFTN TITANDNFGV QSVTVPNTSQ ITGTVDNNHQ HVSATAPNVT SATNKTINLL
ATDTSGNTAT TSFNVTVKPL RDKYRVGTSS TAANPVRIAN ISNNATVSQA DQTTIINSLT
FTETVPNRSY ARASANEITS KTVSNVSRTG NNANVTVTVT YQDGTTSTVT VPVKHVIPEI
VAHSHYTVQG QDFPAGNGSS ASDYFKLSNG SDIADATITW VSGQAPNKDN TRIGEDITVT
AHILIDGETT PITKTATYKV VRTVPKHVFE TARGVLYPGV SDMYDAKQYV KPVNNSWSTN
AQHMNFQFVG TYGPNKDVVG ISTRLIRVTY DNRQTEDLTI LSKVKPDPPR IDANSVTYKA
GLTNQEIKVN NVLNNSSVKL FKADNTPLNV TNITHGSGFS SVVTVSDALP NGGIKAKSSI
SMNNVTYTTQ DEHGQVVTVT RNESVDSNDS ATVTVTPQLQ ATTEGAVFIK GGDGFDFGHV
ERFIQNPPHG ATVAWHDSPD TWKNTVGNTH KTAVVTLPNG QGTRNVEVPV KVYPVANAKA
PSRDVKGQNL TNGTDAMNYI TFDPNTNTNG ITAAWANRQQ PNNQQAGVQH LNVDVTYPGI
SAAKRVPVTV NVYQFEFPQT TYTTTVGGTL ASGTQASGYA HMQNATGLPT DGFTYKWNRD
TTGTNDANWS AMNKPNVAKV VNAKYDVIYN GHTFATSLPA KFVVKDVQPA KPTVTETAAG
AITIAPGANQ TVNTHAGNVT TYADKLVIKR NGNVVTTFTR RNNTSPWVKE ASAATVAGIA
GTNNGITVAA GTFNPADTIQ VVATQGSGET VSDEQRSDDF TVVAPQPNQA TTKIWQNGHI
DITPNNPSGH LINPTQAMDI AYTEKVGNGA EHSKTINVVR GQNNQWTIAN KPDYVTLDAQ
TGKVTFNANT IKPNSSITIT PKAGTGHSVS SNPSTLTAPA AHTVNTTEIV KDYGSNVTAA
EINNAVQVAN KRTATIKNGT AMPTNLAGGS TTTIPVTVTY NDGSTEEVQE SIFTKADKRE
LITAKNHLDD PVSTEGKKPG TITQYNNAMH NAQQQINTAK TEAQQVINNE RATPQQVSDA
LTKVRAAQTK IDQAKALLQN KEDNSQLVTS KNNLQSSVNQ VPSTAGMTQQ SIDNYNAKKR
EAETEITAAQ RVIDNGDATA QQISDEKHRV DNALTALNQA KHDLTADTHA LEQAVQQLNR
TGTTTGKKPA SITAYNNSIR ALQSDLTSAK NSANAIIQKP IRTVQEVQSA LTNVNRVNER
LTQAINQLVP LADNSALKTA KTKLDEEINK SVTTDGMTQS SIQAYENAKR AGQTESTNAQ
NVINNGDATD QQIAAEKTKV EEKYNSLKQA IAGLTPDLAP LQTAKTQLQN DIDQPTSTTG
MTSASIAAFN EKLSAARTKI QEIDRVLASH PDVATIRQNV TAANAAKSAL DQARNGLTVD
KAPLENAKNQ LQHSIDTQTS TTGMTQDSIN AYNAKLTAAR NKIQQINQVL AGSPTVEQIN
TNTSTANQAK SDLDHARQAL TPDKAPLQTA KTQLEQSINQ PTDTTGMTTA SLNAYNQKLQ
AARQKLTEIN QVLNGNPTVQ NINDKVTEAN QAKDQLNTAR QGLTLDRQPA LTTLHGASNL
NQAQQNNFTQ QINAAQNHAA LETIKSNITA LNTAMTKLKD SVADNNTIKS DQNYTDATPA
NKQAYDNAVN AAKGVIGETT NPTMDVNTVN QKAASVKSTK DALDGQQNLQ RAKTEATNAI
THASDLNQAQ KNALTQQVNS AQNVQAVNDI KQTTQSLNTA MTGLKRGVAN HNQVVQSDNY
VNADTNKKND YNNAYNHAND IINGNAQHPV ITPSDVNNAL SNVTSKEHAL NGEAKLNAAK
QEANTALGHL NNLNNAQRQN LQSQINGAHQ IDAVNTIKQN ATNLNSAMGN LRQAVADKDQ
VKRTEDYADA DTAKQNAYNS AVSSAETIIN QTTNPTMSVD DVNRATSAVT SNKNALNGYE
KLAQSKTDAA RAIDALPHLN NAQKADVKSK INAASNIAGV NTVKQQGTDL NTAMGNLQGA
INDEQTTLNS QNYQDATPSK KTAYTNAVQA AKDILNKSNG QNKTKDQVTE AMNQVNSAKN
NLDGTRLLDQ AKQTAKQQLN NMTHLTTAQK TNLTNQINSG TTVAGVQTVQ SNANTLDQAM
NTLRQSIANK DATKASEDYV DANNDKQTAY NNAVAAAETI INANSNPEMN PSTITQKAEQ
VNSSKTALNG DENLAAAKQN AKTYLNTLTS ITDAQKNNLI SQITSATRVS GVDTVKQNAQ
HLDQAMASLQ NGINNESQVK SSEKYRDADT NKQQEYDNAI TAAKAILNKS TGPNTAQNAV
EAALQRVNNA KDALNGDAKL IAAQNAAKQH LGTLTHITTA QRNDLTNQIS QATNLAGVES
VKQNANSLDG AMGNLQTAIN DKSGTLASQN FLDADEQKRN AYNQAVSAAE TILNKQTGPN
TAKTAVEQAL NNVNNAKHAL NGTQNLNNAK QAAITAINGA SDLNQKQKDA LKAQANGAQR
VSNAQDVQHN ATELNTAMGT LKHAIADKTN TLASSKYVNA DSTKQNAYTT KVTNAEHIIS
GTPTVVTTPS EVTAAANQVN SAKQELNGDE RLREAKQNAN TAIDALTQLN TPQKAKLKEQ
VGQANRLEDV QTVQTNGQAL NNAMKGLRDS IANETTVKTS QNYTDASPNN QSTYNSAVSN
AKGIINQTNN PTMDTSAITQ ATTQVNNAKN GLNGAENLRN AQNTAKQNLN TLSHLTNNQK
SAISSQIDRA GHVSEVTATK NAATELNTQM GNLEQAIHDQ NTVKQSVKFT DADKAKRDAY
TNAVSRAEAI LNKTQGANTS KQDVEAAIQN VSSAKNALNG DQNVTNAKNA AKNALNNLTS
INNAQKRDLT TKIDQATTVA GVEAVSNTST QLNTAMANLQ NGINDKTNTL ASENYHDADS
DKKTAYTQAV TNAENILNKN SGSNLDKTAV ENALSQVANA KGALNGNHNL EQAKSNANTT
INGLQHLTTA QKDKLKQQVQ QAQNVAGVDT VKSSANTLNG AMGTLRNSIQ DNTATKNGQN
YLDATERNKT NYNNAVDSAN GVINATSNPN MDANAINQIA TQVTSTKNAL DGTHNLTQAK
QTATNAIDGA TNLNKAQKDA LKAQVTSAQR VANVTSIQQT ANELNTAMGQ LQHGIDDENA
TKQTQKYRDA EQSKKTAYDQ AVAAAKAILN KQTGSNSDKA AVDRALQQVT STKDALNGDA
KLAEAKAAAK QNLGTLNHIT NAQRTDLEGQ INQATTVDGV NTVKTNANTL DGAMNSLQGS
INDKDATLRN QNYLDADESK RNAYTQAVTA AEGILNKQTG GNTSKADVDN ALNAVTRAKA
ALNGADNLRN AKTSATNTID GLPNLTQLQK DNLKHQVEQA QNVAGVNGVK DKGNTLNTAM
GALRTSIQND NTTKTSQNYL DASDSNKNNY NTAVNNANGV INATNNPNMD ANAINGMANQ
VNTTKAALNG AQNLAQAKTN ATNTINNAHD LNQKQKDALK TQVNNAQRVS DANNVQHTAT
ELNSAMTALK AAIADKERTK ASGNYVNADQ EKRQAYDSKV TNAENIISGT PNATLTVNDV
NSAASQVNAA KTALNGDNNL RVAKEHANNT IDGLAQLNNA QKAKLKEQVQ SATTLDGVQT
VKNSSQTLNT AMKGLRDSIA NEATIKAGQN YTDASPNNRN EYDSAVTAAK AIINQTSNPT
MEPNTITQVT SQVTTKEQAL NGARNLAQAK TTAKNNLNNL TSINNAQKDA LTRSIDGATT
VAGVNQETAK ATELNNAMHS LQNGINDETQ TKQTQKYLDA EPSKKSAYDQ AVNAAKAILT
KASGQNVDKA AVEQALQNVN STKTALNGDA KLNEAKAAAK QTLGTLTHIN NAQRTALDNE
ITQATNVEGV NTVKAKAQQL DGAMGQLETS IRDKDTTLQS QNYQDADDAK RTAYSQAVNA
AATILNKTAG GNTPKADVER AMQAVTQANT ALNGIQNLDR AKQAANTAIT NASDLNTKQK
EALKAQVTSA GRVSAANGVE HTATELNTAM TALKRAIADK AETKASGNYV NADANKRQAY
DEKVTAAENI VSGTPTPTLT PADVTNAATQ VTNAKTQLNG NHNLEVAKQN ANTAIDGLTS
LNGPQKAKLK EQVGQATTLP NVQTVRDNAQ TLNTAMKGLR DSIANEATIK AGQNYTDASQ
NKQTDYNSAV TAAKAIIGQT TSPSMNAQEI NQAKDQVTAK QQALNGQENL RTAQTNAKQH
LNGLSDLTDA QKDAVKRQIE GATHVNEVTQ AQNNADALNT AMTNLKNGIQ DQNTIKQGVN
FTDADEAKRN AYTNAVTQAE QILNKAQGPN TSKDGVETAL ENVQRAKNEL NGNQNVANAK
TTAKNALNNL TSINNAQKEA LKSQIEGATT VAGVNQVSTT ASELNTAMSN LQNGINDEAA
TKAAQKYTDA DREKQTAYND AVTAAKTLLD KTAGSNDNKA AVEQALQRVN TAKTALNGDE
RLNEAKNTAK QQVATMSHLT DAQKANLTSQ IESGTTVAGV QGIQANAGTL DQAMNQLRQS
IASKDATKSS EDYQDANADL QNAYNDAVTN AEGIISATNN PEMNPDTINQ KASQVNSAKS
ALNGDEKLAA AKQTAKSDIG RLTDLNNAQR TAANAEVDQA PNLAAVTAAK NKATSLNTAM
GNLKHALAEK DNTKRSVNYT DADQPKQQAY DTAVTQAEAI TNANGSNANE TQVQAALNQL
NQAKNDLNGD NKVAQAKESA KRALASYSNL NNAQSTAAIS QIDNATTVAG VTAAQNTANE
LNTAMGQLQN GINDQNTVKQ QVNFTDADQG KKDAYTNAVT NAQGILDKAH GQNMTKAQVE
AALNQVTTAK NALNGDANVR QAKSDAKANL GTLTHLNNAQ KQDLTSQIEG ATTVNGVNGV
KTKAQDLDGA MQRLQSAIAN KDQTKASENY IDADPTKKTA FDNAITQAES YLNKDHGANK
DKQAVEQAIQ SVTSTENALN GDANLQRAKT EAIQAIDNLT HLNTPQKTAL KQQVNAAQRV
SGVTDLKNSA TSLNNAMDQL KQAIADHDTI VASGNYTNAS PDKQGAYTDA YNAAKNIVNG
SPNVITNAAD VTAATQRVNN AETGLNGDTN LATAKQQAKD ALRQMTHLSD AQKQSITGQI
DSATQVTGVQ SVKDNATNLD NAMNQLRNSI ANKDDVKASQ PYVDADRDKQ NAYNTAVTNA
ENIINATSQP TLDPSAVTQA ANQVSTNKTA LNGAQNLANK KQETTANINQ LSHLNNAQKQ
DLNTQVTNAP NISTVNQVKT KAEQLDQAME RLINGIQDKD QVKQSVNFTD ADPEKQTAYN
NAVTAAENII NQANGTNANQ SQVEAALSTV TTTKQALNGD RKVTDAKNNA NQTLSTLDNL
NNAQKGAVTG NINQAHTVAE VTQAIQTAQE LNTAMGNLKN SLNDKDTTLG SQNFADADPE
KKNAYNEAVH NAENILNKST GTNVPKDQVE AAMNQVNATK AALNGTQNLE KAKQHANTAI
DGLSHLTNAQ KEALKQLVQQ STTVAEAQGN EQKANNVDAA MDKLRQSIAD NATTKQNQNY
TDASQNKKDA YNNAVTTAQG IIDQTTSPTL DPTVINQAAG QVSTTKNALN GNENLEAAKQ
QASQSLGSLD NLNNAQKQTV TDQINGAHTV DEANQIKQNA QNLNTAMGNL KQAIADKDAT
KATVNFTDAD QAKQQAYNTA VTNAENIISK ANGGNATQAE VEQAIKQVNA AKQALNGNAN
VQHAKDEATA LINSSNDLNQ AQKDALKQQV QNATTVAGVN NVKQTAQELN NAMTQLKQGI
ADKEQTKADG NFVNADPDKQ NAYNQAVAKA EALISATPDV VVTPSEITAA LNKVTQAKND
LNGNTNLATA KQNVQHAIDQ LPNLNQAQRD EYSKQITQAT LVPNVNAIQQ AATTLNDAMT
QLKQGIANKA QIKGSENYHD ADTDKQTAYD NAVTKAEELL KQTTNPTMDP NTIQQALTKV
NDTNQALNGN QKLADAKQDA KTTLGTLDHL NDAQKQALTT QVEQAPDIAT VNNVKQNAQN
LNNAMTNLNN ALQDKTETLN SINFTDADQA KKDAYTNAVS HAEGILSKAN GSNASQTEVE
QAMQRVNEAK QALNGNDNVQ RAKDAAKQVI TNANDLNQAQ KDALKQQVDA AQTVANVNTI
KQTAQDLNQA MTQLKQGIAD KDQTKANGNF VNADTDKQNA YNNAVAHAEQ IISGTPNANV
DPQQVAQALQ QVNQAKGDLN GNHNLQVAKD NANTAIDQLP NLNQPQKTAL KDQVSHAELV
TGVNAIKQNA DALNNAMGTL KQQIQANSQV PQSVDFTQAD QDKQQAYNNA ANQAQQIANG
IPTPVLTPDT VTQAVTTMNQ AKDALNGDEK LAQAKQEALA NLDTLRDLNQ PQRDALRNQI
NQAQALATVE QTKQNAQNVN TAMSNLKQGI ANKDTVKASE NYHDADADKQ TAYTNAVSQA
EGIINQTTNP TLNPDEITRA LTQVTDAKNG LNGEAKLATE KQNAKDAVSG MTHLNDAQKQ
ALKGQIDQSP EIATVNQVKQ TATSLDQAMD QLSQAINDKA QTLADGNYLN ADPDKQNAYK
QAVAKAEALL NKQSGTNEVQ AQVESITNEV NAAKQALNGN DNLANAKQQA KQQLANLTHL
NDAQKQSFES QITQAPLVTD VTTINQKAQT LDHAMELLRN SVADNQTTLA SEDYHDATAQ
RQNDYNQAVT AANNIINQTT SPTMNPDDVN GATTQVNNTK VALDGDENLA AAKQQANNRL
DQLDHLNNAQ KQQLQSQITQ SSDIAAVNGH KQTAESLNTA MGNLINAIAD HQAVEQRGNF
INADTDKQTA YNTAVNEAAA MINKQTGQNA NQTEVEQAIT KVQTTLQALN GDHNLQVAKT
NATQAIDALT SLNDPQKTAL KDQVTAATLV TAVHQIEQNA NTLNQAMHGL RQSIQDNAAT
KANSKYINED QPEQQNYDQA VQAANNIINE QTATLDNNAI NQAATTVNTT KAALHGDVKL
QNDKDHAKQT VSQLAHLNNA QKHMEDTLID SETTRTAVKQ DLTEAQALDQ LMDALQQSIA
DKDATRASSA YVNAEPNKKQ SYDEAVQNAE SIIAGLNNPT INKGNVSSAT QAVISSKNAL
DGVERLAQDK QTAGNSLNHL DQLTPAQQQA LENQINNATT RGEVAQKLTE AQALNQAMEA
LRNSIQDQQQ TEAGSKFINE DKPQKDAYQA AVQNAKDLIN QTNNPTLDKA QVEQLTQAVN
QAKDNLHGDQ KLADDKQHAV TDLNQLNGLN NPQRQALESQ INNAATRGEV AQKLAEAKAL
DQAMQALRNS IQDQQQTESG SKFINEDKPQ KDAYQAAVQN AKDLINQTGN PTLDKSQVEQ
LTQAVTTAKD NLHGDQKLAR DQQQAVTTVN ALPNLNHAQQ QALTDAINAA PTRTEVAQHV
QTATELDHAM ETLKNKVDQV NTDKAQPNYT EASTDKKEAV DQALQAAESI TDPTNGSNAN
KDAVDQVLTK LQEKENELNG NERVAEAKTQ AKQTIDQLTH LNADQIATAK QNIDQATKLQ
PIAELVDQAT QLNQSMDQLQ QAVNEHANVE QTVDYTQADS DKQNAYKQAI ADAENVLKQN
ANKQQVDQAL QNILNAKQAL NGDERVALAK TNGKHDIDQL NALNNAQQDG FKGRIDQSND
LNQIQQIVDE AKALNRAMDQ LSQEITDNEG RTKGSTNYVN ADTQVKQVYD ETVDKAKQAL
DKSTGQNLTA KQVIKLNDAV TAAKKALNGE ERLNNRKAEA LQRLDQLTHL NNAQRQLAIQ
QINNAETLNK ASRAINRATK LDNAMGAVQQ YIDEQHLGVI SSTNYINADD NLKANYDNAI
ANAAHELDKV QGNAIAKAEA EQLKQNIIDA QNALNGDQNL ANAKDKANAF VNSLNGLNQQ
QQDLAHKAIN NADTVSDVTD IVNNQIDLND AMETLKHLVD NEIPNAEQTV NYQNADDNAK
TNFDDAKRLA NTLLNSDNTN VNDINGAIQA VNDAIHNLNG DQRLQDAKDK AIQSINQALA
NKLKEIEASN ATDQDKLIAK NKAEELANSI INNINKATSN QAVSQVQTAG NHAIEQVHAN
EIPKAKIDAN KDVDKQVQAL IDEIDRNPNL TDKEKQALKD RINQILQQGH NGINNAMTKE
EIEQAKAQLA QALQDIKDLV KAKEDAKQDV DKQVQALIDE IDQNPNLTDK EKQALKYRIN
QILQQGHNDI NNALTKEEIE QAKAQLAQAL QDIKDLVKAK EDAKNAIKAL ANAKRDQINS
NPDLTPEQKA KALKEIDEAE KRALQNVENA QTIDQLNRGL NLGLDDIRNT HVWEVDEQPA
VNEIFEATPE QILVNGELIV HRDDIITEQD ILAHINLIDQ LSAEVIDTPS TATISDSLTA
KVEVTLLDGS KVIVNVPVKV VEKELSVVKQ QAIESIENAA QQKINEINNS VTLTLEQKEA
AIAEVNKLKQ QAIDHVNNAP DVHSVEEIQQ QEQAHIEQFN PEQFTIEQAK SNAIKSIEDA
IQHMIDEIKA RTDLTDKEKQ EAIAKLNQLK EQAIQAIQRA QSIDEISEQL EQFKAQMKAA
NPTAKELAKR KQEAISRIKD FSNEKINSIR NSEIGTADEK QAAMNQINEI VLETIRDINN
AHTLQQVEAA LNNGIARISA VQIVTSDRAK QSSSTGNESN SHLTIGYGTA NHPFNSSTIG
HKKKLDEDDD IDPLHMRHFS NNFGNVIKNA IGVVGISGLL ASFWFFIAKR RRKEDEEEEL
EIRDNNKDSI KETLDDTKHL PLLFAKRRRK EDEEDVTVEE KDSLNNGESL DKVKHTPFFL
PKRRRKEDEE DVEVTNENTD EKVLKDNEHS PLLFAKRRKD KEEDVETTTS IESKDEDVPL
LLAKKKNQKD NQSKDKKSAS KNTSKKVAAK KKKKKAKKNK K
