EBH_STAAR
ID EBH_STAAR Reviewed; 10746 AA.
AC Q6GGX3;
DT 02-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT 19-JUL-2004, sequence version 1.
DT 25-MAY-2022, entry version 105.
DE RecName: Full=Extracellular matrix-binding protein ebh;
DE AltName: Full=ECM-binding protein homolog;
DE Flags: Precursor;
GN Name=ebh; OrderedLocusNames=SAR1447;
OS Staphylococcus aureus (strain MRSA252).
OC Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC Staphylococcus.
OX NCBI_TaxID=282458;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MRSA252;
RX PubMed=15213324; DOI=10.1073/pnas.0402521101;
RA Holden M.T.G., Feil E.J., Lindsay J.A., Peacock S.J., Day N.P.J.,
RA Enright M.C., Foster T.J., Moore C.E., Hurst L., Atkin R., Barron A.,
RA Bason N., Bentley S.D., Chillingworth C., Chillingworth T., Churcher C.,
RA Clark L., Corton C., Cronin A., Doggett J., Dowd L., Feltwell T., Hance Z.,
RA Harris B., Hauser H., Holroyd S., Jagels K., James K.D., Lennard N.,
RA Line A., Mayes R., Moule S., Mungall K., Ormond D., Quail M.A.,
RA Rabbinowitsch E., Rutherford K.M., Sanders M., Sharp S., Simmonds M.,
RA Stevens K., Whitehead S., Barrell B.G., Spratt B.G., Parkhill J.;
RT "Complete genomes of two clinical Staphylococcus aureus strains: evidence
RT for the rapid evolution of virulence and drug resistance.";
RL Proc. Natl. Acad. Sci. U.S.A. 101:9786-9791(2004).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Single-pass membrane
CC protein {ECO:0000305}.
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DR EMBL; BX571856; CAG40444.1; -; Genomic_DNA.
DR RefSeq; WP_001109390.1; NC_002952.2.
DR SMR; Q6GGX3; -.
DR PRIDE; Q6GGX3; -.
DR KEGG; sar:SAR1447; -.
DR HOGENOM; CLU_222673_0_0_9; -.
DR OMA; NRATKEM; -.
DR OrthoDB; 562at2; -.
DR Proteomes; UP000000596; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR011439; DUF1542.
DR InterPro; IPR026361; Ebh_dom.
DR InterPro; IPR020840; Extracell_matrix-bd_GA.
DR InterPro; IPR002988; GA_module.
DR InterPro; IPR009063; Ig/albumin-bd_sf.
DR InterPro; IPR005877; YSIRK_signal_dom.
DR Pfam; PF07564; DUF1542; 8.
DR Pfam; PF01468; GA; 19.
DR Pfam; PF04650; YSIRK_signal; 1.
DR SMART; SM00844; GA; 54.
DR SUPFAM; SSF46997; SSF46997; 106.
DR TIGRFAMs; TIGR04264; hyperosmo_Ebh; 1.
DR TIGRFAMs; TIGR01168; YSIRK_signal; 1.
PE 3: Inferred from homology;
KW Cell membrane; Membrane; Repeat; Signal; Transmembrane;
KW Transmembrane helix.
FT SIGNAL 1..39
FT /evidence="ECO:0000255"
FT CHAIN 40..10746
FT /note="Extracellular matrix-binding protein ebh"
FT /id="PRO_0000345980"
FT TRANSMEM 10552..10572
FT /note="Helical"
FT /evidence="ECO:0000255"
FT DOMAIN 2520..2576
FT /note="FIVAR 1"
FT DOMAIN 2606..2662
FT /note="FIVAR 2"
FT DOMAIN 2683..2746
FT /note="FIVAR 3"
FT DOMAIN 2776..2832
FT /note="FIVAR 4"
FT DOMAIN 2860..2915
FT /note="FIVAR 5"
FT DOMAIN 2943..2998
FT /note="FIVAR 6"
FT DOMAIN 3026..3081
FT /note="FIVAR 7"
FT DOMAIN 3150..3208
FT /note="FIVAR 8"
FT DOMAIN 3276..3335
FT /note="FIVAR 9"
FT DOMAIN 3403..3461
FT /note="FIVAR 10"
FT DOMAIN 3529..3587
FT /note="FIVAR 11"
FT DOMAIN 3655..3713
FT /note="FIVAR 12"
FT DOMAIN 3781..3839
FT /note="FIVAR 13"
FT DOMAIN 3907..3965
FT /note="FIVAR 14"
FT DOMAIN 4033..4091
FT /note="FIVAR 15"
FT DOMAIN 4159..4217
FT /note="FIVAR 16"
FT DOMAIN 4285..4343
FT /note="FIVAR 17"
FT DOMAIN 4411..4469
FT /note="FIVAR 18"
FT DOMAIN 4537..4595
FT /note="FIVAR 19"
FT DOMAIN 4663..4721
FT /note="FIVAR 20"
FT DOMAIN 4789..4847
FT /note="FIVAR 21"
FT DOMAIN 4915..4973
FT /note="FIVAR 22"
FT DOMAIN 5041..5099
FT /note="FIVAR 23"
FT DOMAIN 5167..5225
FT /note="FIVAR 24"
FT DOMAIN 5293..5351
FT /note="FIVAR 25"
FT DOMAIN 5419..5477
FT /note="FIVAR 26"
FT DOMAIN 5545..5603
FT /note="FIVAR 27"
FT DOMAIN 5671..5729
FT /note="FIVAR 28"
FT DOMAIN 5797..5855
FT /note="FIVAR 29"
FT DOMAIN 5923..5981
FT /note="FIVAR 30"
FT DOMAIN 6049..6107
FT /note="FIVAR 31"
FT DOMAIN 6175..6232
FT /note="FIVAR 32"
FT DOMAIN 6300..6358
FT /note="FIVAR 33"
FT DOMAIN 6426..6484
FT /note="FIVAR 34"
FT DOMAIN 6552..6610
FT /note="FIVAR 35"
FT DOMAIN 6678..6736
FT /note="FIVAR 36"
FT DOMAIN 6804..6862
FT /note="FIVAR 37"
FT DOMAIN 6930..6988
FT /note="FIVAR 38"
FT DOMAIN 7056..7114
FT /note="FIVAR 39"
FT DOMAIN 7182..7240
FT /note="FIVAR 40"
FT DOMAIN 7308..7366
FT /note="FIVAR 41"
FT DOMAIN 7434..7492
FT /note="FIVAR 42"
FT DOMAIN 7560..7618
FT /note="FIVAR 43"
FT DOMAIN 7686..7744
FT /note="FIVAR 44"
FT DOMAIN 7812..7870
FT /note="FIVAR 45"
FT DOMAIN 7938..7996
FT /note="FIVAR 46"
FT DOMAIN 8064..8125
FT /note="FIVAR 47"
FT DOMAIN 8190..8251
FT /note="FIVAR 48"
FT DOMAIN 8316..8374
FT /note="FIVAR 49"
FT DOMAIN 8442..8500
FT /note="FIVAR 50"
FT DOMAIN 8568..8625
FT /note="FIVAR 51"
FT DOMAIN 8693..8751
FT /note="FIVAR 52"
FT DOMAIN 8819..8877
FT /note="FIVAR 53"
FT DOMAIN 8945..9003
FT /note="FIVAR 54"
FT DOMAIN 9071..9129
FT /note="FIVAR 55"
FT DOMAIN 9197..9255
FT /note="FIVAR 56"
FT DOMAIN 9323..9377
FT /note="FIVAR 57"
FT DOMAIN 9445..9504
FT /note="FIVAR 58"
FT DOMAIN 9699..9755
FT /note="FIVAR 59"
FT REGION 41..174
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 246..274
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1340..1372
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 7066..7085
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 10492..10530
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 10649..10746
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 41..132
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 133..155
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 156..174
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1356..1372
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 10492..10521
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 10649..10722
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 10723..10746
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 10746 AA; 1157163 MW; 8471C3E2EA3B0248 CRC64;
MNYRDKIQKF SIRKYTVGTF STVIATLVFL GLNTSQAQAA ETNQPASALK QKQQNGDTQT
ENREVEVQNS QNGQSLSAPI ENEQPNNNQT NHVDASAVQS STTEHDQPVS QNEQAKKDTA
AATPTQSAKA ASKHEQSESR AANKKENDNK ATHVESHEAN VVTASDSSDS GNVQHDRNEL
QAFFDANYHD YRFIDRENAD SGTFNYVKGI FDKINTLLGS NDPINNKDLQ LAYKELEQAV
ALIRTMPQRQ QTSRRSSRIQ TRSIESRAAE PRSVSDYQNA NSSYYVENAN DGSGYPVGTY
INASSKGAPY NLPTTPWNTL KASDAKEIAL ITAKQTGDGY QWVIKFNKGH APHENMIYWF
ALPAGQTPVG RTEFVTVNAD GTNVQWSNGA GAGANKPLPE MWPYGVNDSR SWDYKIRNRS
GQVIYDWPTV HINSLKDLAR ASDYFSEAGA TPATKAFGRQ TFEYINGERP TESPGVPKVY
TFIGKGDASY TISFKTQGPT IDKLYYAAGG RALEYNQLFM YSQLYVESTQ DYQQRLNGLR
QVVNRTYRIG TTKRVEVSQG NVQTKKVLES TNLNIDDFMD DPLSYVKTPS NKVLGFYPTS
ANTNAFRPGG VNPLNEYQLS QLFTDDKLQQ AARTGSPIRL MIGFDYPDAF GNGETLVPVN
LTVLPEIQHN IKFFKNDDGQ NIADKPASKQ AGHPVFYVYA GNQGNASVNL GGSVTSIQPL
RINLTSNENF TDKDWQITGI PRTLHIENST NRTNNARERN IELVGNLLPG DYFGTIRFGR
KEQLFEIRVK PHTPRITTTA EELRGTALQK VPVTVTDIPL DPSALVYLVI PTSQTRDGGS
EADQIPSGYT KIATGTPDGV HSTITIRPED YVVFIPPVGN QIRALIFYNN VVASNMSNAV
TILPDDIPPT INNPVGLNAK YYRGDEVSFT MGVSDRHSGL KSTTITTLPS GWTSNLTKSD
KKNGSLAISG RVSMNQAYNS DITFKVSATD NVNNTTNDSQ SKHVTVHVGK ISDDAHPIVL
GNSEKVVVVN PTALTGDEKQ RITTAFMNKN QNIRGYLASS NPVTVDNHGN VTLQYRDGSS
TTLDATNVMT YEPVVKPEYQ TANAAKTATV TIAKGQSFNI GDIKQYFTLS NGQAIPSSSF
TNITSDRTIP TAQEVSQMNA GTQLYHIVAT NAYHKDTEDF YITLKIIDVK QPEGDQRVYR
MSTYDITTDE ISKVKQAFIN ANRDAISFAE GDISVTNTPN GSNVSTITVN INKGRLTKSF
TSNLNNMNFL RWVNFPQDYT VTWTNAKIAN RPTDGGLSWS DDHKSLIYRY DATLGTQITT
NDILTLLKAT TTVPGLRNNI AGNEKAQAEA GGRPNYKTTG YSQSNPTSDG QRQFTLNGQV
IQIMDIINPS NGFGGQPVTN SNVRANHSNS TVVSVNESAA NGAGAFTIDH VVKNNSTHNA
ADAVYKAQLY LSPYGPKQYV EHLNQNTDNT NEAINIYFVP SDLVNPTISV GNYTNHQVFS
GETFTNTITA NDNFGVQSVT VPTTSQLTGT VDNNHQHVSA TAPNVTSTTN KTINLVATDT
SGNTATTSFN VTIKPLRDKY RVGTSSTAAN PVRIANISNN ATVSQADQTA IINSLTFTSN
APNRNYATAS ANEITSKTVS NVSRTGNNAQ VTVTVTYQDG TTSTVTVPVK RVIPEIVAHS
HYTVQGQDFP TGNGASASDY FKLSNGSAIP DATITWVSGQ APNKNNTTIG QDINVTAHIL
IDGETTPITK TATYKVVRTV PKQVFETARG VLYPGVSDMY DAKQYVKPVN NSWSTNAQHM
NFQFTNSYGP SKDVVGISTR DIRVTYDNHQ TQIIKILSKV KPDPPRIDGN SVTYKAGLTN
QQIKINNVLS SSSIKLFKAD NTPLTITNTT YGSGNTAVVT VSDALPNGEI KARSSISMNN
VTYTTQDEHG RAIDVTRNES VDSNDSASVH VTPQLQATTE GAVFIKGGDG FDFGHVERFI
QNPPHGATVA WHDNPDTWKN TVGNTHKTAV VTLPNGQGTR NVEVPVKVYP VANAKAPSRD
VKGQNLTNGT DAINYITFDP NTNTNGITAV WANRQQPNNQ QAGVQHLNVD VTYPGISAAK
RVPVTVNVYQ FEFPQTSYTT TVGGTLASGT QASGYAHIQN ATGLPTDGFT YKWNNAATGT
NDANWAAMNK PNTAQVINAK YDVIYNGHTF ATSLPAKFVV KDVQPAKPTV TETAAGVITI
APGANQTVNT HAGNVTTYAD KLVIKRNGNV VTTFTRHNNT SPWVKEASAA NVAGIAGTNN
GITVAAGTFN PADTIQAVAT QGSGETISDE QRSDDFTVVA PQPNQATTKI WQNGHVDITP
NNPSGHLINP TQAMDIAYTE KVGNGAEHSK TLNAVRGQNN QWTIANKPDY VTLDAHTGKV
TFNANTIKPN SAITITPKAG TGHSASSNPS TLTAPAAHTV NTTEIVKDYG SNVTAAEINN
AVQVANKRTA TIKNGTAMPT NLAGGSTTTI PVTVTYNDSS TEEVQESIFT KADKRELITA
KNHLDDPVST DGKKPGTITQ YNNAIHNAQQ QINTAKTEAQ QVINDERATP QQVNAALSKV
QAAQTKINEA KALLQNKEDN SQLVTSKNNL QSSVNQVPST TGMTQQSIDN YNAKKREAES
EITAAQRVID NGDATAQQIS DEKHRVDNAL TALNQAKQNL TADTHELEQA VHQLNRTGTT
TGKKPASITA YNNSIRALQS DLTSAKNSAN AIIQKPIRSV QEVQTALTNV NRVNDRLTLA
INQLVPLADN SALRTAKTKL DEEINKSVTT DGMTQSSIQA YENAKRAGQT ESTNAQNVIN
NGDATDQQIA AKKTKVEEKY NGLKQAIAGL TPDLAPLQAA KTQLQNDIDQ PTSTTGMTSA
SVAAFNDKLS AARTKIQEID RVLASHPDVA TIRQNVTAAN ATKTALDQAR NGLTVDKAPL
ENAKNQLQQS IDTQTSTTGM TQDSINAYNA KLTAARNKIQ QINQVLAGSP TVDQINTNTS
AANQAKSDLD HARQALTPDK APLQTAKTQL EQSINQPTDT TGMTTASLNA YNQKLQAARQ
KLTEINQVLN GNPTVQNIND KVAEANQAKD QLNTARQGLT LDRQPAFTTL HGASNLNQAQ
QNNFTQQINA APNHAALETI KSNITALNNA MTKLKDSVAD NNSIKSGQNY TDATTANKQA
YDNAVNAAKG VIGETTNPTM DVNTVNQKAE TVKSTKGALD GQQNLQRAKT EATNAITHAS
DLNQTQKNAL TQQVNNAQNV QAVNDIKQTT QSLNTAMTGL KRGVANHNQV VQSDNYVNAD
TNKKNDYNNA YNHANDIING NAQHPVITPS DVNNALSNVT SKEQALNGEA KLNAAKQEAN
TALGQLNNLN NAQRQNLQSQ INGAHQIETV NTIKQNATNL NSAMGNLRQA VADKEQVKRT
EDYADADTAK QNAYNSAVSS AETIINQTTN PTMSVNDVNS ATSAVTTNKN ALNGDEKLAQ
SKTDAASAID ALPHLNNAQK ADVKSKINAA SNIAGVNTVK QQGTDLNTAM GNLQGAINDE
QTTLNSQNYQ DATPSKKTAY TNAVQAAKDI LNKSNGQNKT KDQVTEAMNQ VNSAKNNLDG
TRLLDQAKQT AKQQLNNMTH LTTAQKTHLT NQINSGTTVA GVHTAQSNAN TLDQAMNTLR
QSIANKDATK ASEDYVDANN DKQTAYNNAV AAAETIINAN SNPEMNPSTI TQKAEQVNSS
KTALNGDENL ATAKLNAKTY LNTLTSITDA QKNNLISQIS SATRVSSVDT VKQNAQHLDQ
AMASLQNGIN NESQVKSSEK YRDADTNKQQ EYDNAITAAK AILNKQHGPN TAQNAVEAAL
QRVKTAKNAL NGDAKLIAAQ NAAKQHLGTL THITTAQRND LTNQISQATN LAGVESVKQS
ANSLDGAMGN LQTAINDKSG TLASQNFLDA DEQKRNAYNQ AVSNAETILN KQTGPNTAKT
AVEQALNNVN SAKHALNGTQ NLNNAKQAAI TAINGASDLN QHQKDALKAQ ANGAQRVSNA
QDVQRNATEL NTAMGQLQHA IADKTTTLAS SKFVNADSTK QNVYTTKVTN AEHIISGTPT
VVTTPSEVTA AANQVNSAKQ ELNGDERLRV AKQNANTAID ALTQLNTPQK AKLKEQVGQA
NRLEDVQSVQ TNGQSLNNAM KGLRDSIANE TTVKASQNYT DASPNNQSTY NSAVSNAKGI
INQTNNPTMD ASAITQATTQ VNNAKNGLNG AENLRNAQNT AKQNLNTLSH LTNNQKSAIS
SQIDRAGHVS EVTAAKNAAT ELNTQMGNLE QAIHDQNTVK QGVNFTDADK AKRDAYTNAV
SRAETILNKT QGANTPKQDV EAAIQSVTSA KNALNGDQNV TNAKNAAKHA LNNLTSINNA
QKRDLTTKID QATTVSGVEA VSNTGTQLNT AMANLQNGIN DKTNTLASEN YHDADSDKKT
AYTQAVTNAE NILNKNSGSN LDKAAVENAL SQVTNAKGAL NGNHNLEQAK SNANTTINGL
QHLTTAQKDK LKQQVQQAQN VAGVDTVKSS ANTLNGAMGT LRNSIQDNAA TKNGQNYLDA
TESNKTNYNN AVDSANGVIN ATSNPNMDAN AINQIATQVT STKNALDGTH NLTQAKQTAT
NAIDGATNLN KAQKDALKAQ VTSAQRVANV TSIQQTANEL NTAMGQLQHG IDDENATKQT
QKYRDAEQSK KTAYDQAVAA AKAILNKQTG SNSDKAAVDR ALQQVTSTKD ALNGDAKLAE
AKAAAKQNLG TLNHITNAQR TDLEGQINQA TTVDGVNTVK TNANTLDGAM NSLQGSINDK
DATLRNQNYL DADESKRNAY TQAVTAAEGI LNKQTGGNTS KADVDNALNA VTRAKAALNG
ADNLRNAKTS ATNTINGLPH LTQLQKDNLK HQVEQAQNVA GVNGVKDKGN TLNTAMGALR
TSIQNDNTTK TSQNYLDASD INKNNYNTAV NNANGVINAT NNPNMDANAI NGMANQVNTT
KAALNGVQNL AQAKTNATNT INNAHDLNQK QKDALKTQVN NAQRVSDANN VQHTATELNG
AMTVLKAAIA DKERTKASGN YVNADQEKRQ AYDSKVTNAE NIINGTPNAT LTVNDVNSAT
SQVNAAKTVL NGDNNLRVAK EHANNTIDGL AQLNNAQKAK LKEQVQSATT LDGVQTVKNS
SQTLNTAMKG LRDSIANEAT IKAGQNYTDA SPNNRNEYDS AVTAAKAIIN QTSNPTMEPN
TITQATSQVT TKEQALNGAQ NLAQAKTTAK NNLNNLTSIN NAQKDALTRS IDGATTVAGV
NQETVKATEL NNAMHSLQNG INDETQTKQT QKYLDAEPSK KSAYDQAVNA AKAILTKASG
QNVDKAAVEQ ALQNVNSTKT ALNGDAKLNE AKAAAKQTLG TLTHINNAQR TALDNEITQA
TNVEGVNTVK AKAQQLDGAM GQLETSIRDK DTTLQSQNYQ DADDAKRTAY SQAVNAAATI
LNKTSGGNTP KADVERAMQA VTQANTALNG IQNLERAKQA ANTAITNASD LNTKQKEALK
AQVTSAGRVS VANGVEHTAT ELNTAMTALK RAIADKADTK ASGNYVNADA NKRQAYDEKV
TAAENIVSGT PTPTLTPSDV TNAATQVTNA KTQLNGNHNL EVAKQNANTA IDGLTSLNGP
QKAKLKEQVG QATTLPNVQT VRDNAQTLNT AMKGLRDSIA NEATIKAEQN YTDASPNNRS
EYDSAVTAAK AIIGQTSSPT MNAQEINQAK DQVTAKQQAL NGQENLTNAQ INAKQHLNGL
SDLTNAQKDA AKRQIEGATH VSEVTQAQNN ADALNTAMTN LKNGIQDQNT IKQGVNFTDA
DEAKRNAYTN AVTQAEQILN KVQGPNTAKD NVESALQNVQ RAKNDLNGNQ NVANAKTTAK
NALNNLTSIN NAQNEALKSQ IDSATTVAGV NQVSATASEL NTAMSNLQNG INDEAATKAA
QKYTDADSDK QTAYNDAVTA AKTLLDKTAG TNDNKAAVEQ ALQRVNTAKT ALNGDARLNQ
AKNTAKQQLA TMSHLTDAQK ANLTSQIERG TTVAGVQGIQ ANAGTLNEAM NQLRQSIASK
DATKASEDYH DANTDLQNAY NDAVTNAEGI ISATNNPEMN PDTINQKASQ VNSAKSALNG
DEKLAAAKQT AKSDIGRLTD LNNAQRTAAN AEVDQAPNLA AVTAAKNKAT SLNTAMGNLK
HALAEKDNTK RSVNYTDADQ PKQQAYDTAV TQAEAITNAN GSNANETQVQ AALNQLNQAK
NDLNGDNKVA QAKETAKRAL ASYSNLNNAQ STAATSQIDN ATTVAGVTAA QNTANELNTA
MGQLQNGIND QNTVKQQVNF TDADQGKKDA YTNAVTNAQG ILDKAHGQNM TKAQVEAALN
QVTTAKNALN GDANVRQAKS DAKANLGTLT HLNNAQKQDL TSQIEGATTV NGVNGVKTKA
QDLDGAMQRL QSAIANKDQT KASENYIDAD PTNKTAFDNA ITQAESYLNK DHGANKDKQA
VEQAIQSVTS TENALNGDAN LQRAKTEATQ AIDNLTHLNT PQKTALKQQV NAAQRVSGVT
DLKNSATSLN NAMDQLKQAI ADHDTIVAGG NYTNASPDKQ GAYTDAYNAA KNIVNGSPNV
ITNAADVTAA TQRVNNAETG LNGDTNLATA KQQAKDALRQ MTHLSDAQKQ SITVQIDNAT
QVTGVQSVKD NATNLDNAMN QLRNSIANKD EVKASQPYVD ADRDKQNAYN TAVTSAENII
NATSQPTLDP SAVTQAANQV NTNKTALNGA QNLANKKQET TANINQLSHL NNAQKQDLNT
QVTNAPNIST VSQVKTKAEQ LDQAMERLIN GIQDKDQVKQ SVNFTDADPE KQTAYNNAVT
AAENIINQAN GTNANQSQVE AALSTVTTTK QALNGDRKVT DAKNNANQTL STLDNLNNAQ
KGAVTGNINQ AHTVAEVTQA IQTAQELNTA MGNLKNSLND KDTTLGSQNF ADADPEKKNA
YNEAVRNAEN ILNKSTGTNV SKDQVEAAMN QVNTTKAALN GTQNLEKAKQ HANTAIDGLS
HLTNAQKEAL KQLVQQSTTV AEAQGNEQKA NNVDAAMDKL RQSIADNATT KQNQNYTDSS
PNKKDAYNNA VTTAQGIIDQ TTSPTLDPTV INQAAGQVST TKNALNGNEN LEAAKQQATQ
SLGSLDNLNN AQKQAVTDQI NGAHTVDEAN QIKQNAQNLN TAMGNLKQAI ADKDATKATV
NFTDADQAKQ QAYNTAVTNA ENIISKANGG NATQTEVEQA IQQVNAAKQA LNGNANVQHA
KDEATALINS SNDLNQAQKD ALKQQVQNAT TVAGVNNVKQ TAQELNNAMT QLKQGIADKE
QTKADGNFVN ADPDKQNAYK QAVAKAEALI SGTPDVVVTP SEITAALNKV TQAKNDLNGN
TNLATTKQNV QHAIDQLPNL NQAQRDEYSK QITQATLVPN VNAIQQAATT LNDAMTQLKQ
GIANKAQIKG SENYHDADTD KQTAYDNAVT KAEELLKQTT NPTMDPNTIQ QALTKVNDTN
QALNGNQKLA DAKQAAKTNL GTLDHLNDAQ KQALTTQVEQ APDIATVNNV KQNAQNLNNA
MTNLSNALQD KTETLNSINF TDADQAKKDA YTNAVAHAEG ILSKANGSNA SQTEVEQAMQ
RVNEAKQALN GNDNVQRAKD AAKQVITNAN DLNQAQKDAL KQQVDAAQTV ANVNTIKQTA
QDLNQAMTQL KQGIADKDQT KANGNFVNAD TDKQNAYNNA VAHAEQIISG TPNANVDPQQ
VAQALQQVTQ AKGDLNGNHN LQVAKDNANT AIDQLPNLNQ TQKTALKDQV SHAELVTGVN
AIKQNADALN NAMGTLKQQI QANSQVPQSV DFTQADQDKQ QAYNNAANQA QQIANGTPTP
VLTPDAVTQA VTTMNQAKDA LNGDEKLAQA KQDAIANLDT LRDLNQPQRD ALRNQINQAQ
ALATVEQTKQ NAQNVNTAMS NLKQGIANKD TVKASENYHD ADADKQTAYT NAVSQAEGII
NQTTNPMLNP DDITRALTQV TDAKNGLNGE AKLATEKQNA KDAVNAMTHL NDAQKQALKG
QIDQSPEIAI VNQVKQTATS LDHAMDQLSQ AINDKAQTLA DGNYLNADPD KQNAYKQAVA
KAEALLNKQS GTNEVQAQVE SITNEVNAAK QALNGNDNLA NAKQQAKQQL ANLTHLNDAQ
KQSFESQITQ APLVTDVTTI NQKAQALDHA MDQLSQAIND KAQTLADGNY LNADPDKQNA
YKQAVAKAEA LLNKQSGTNE VQAQVESITN EVNAAKQALN GNDNLANAKQ QAKQQLANLT
HLNDAQKQSF ESQITQAPLV TDVTTINQKA QALDHAMELL RNSVADNQAT LASEDYHDAT
AQRQNDYNQA VTATNNIINQ TTSPTMNPDE VNRATTQVNN TKVALDGDEN LVAAKQQANN
RLDQLDHLNN AQKQQLQSQI TQSSDIAAVN GHKQTAESLN TAMGNLINAI ADHQTVEQLG
NFVNADTDKQ TAYTTAVNEA EAMINKQTGQ NANQTEVEQA ITKVQTTLQA LNGDHNLQVA
KANATQAIDA LTSLNDPQKT ALKDQVTAAT LVTAVHQIEQ NANTLNQAMH GLRESIQDNA
ATKANSKYIN EDQSEQQNYD QAVQAANNII NEQTATLDNN AINQAATTVN TTKAALHGDV
KLQNDKDHAK QTVSQLTHLN NAQKHMEDTL IDSETTRTAV NHDLTEAQAL DQLMDALQQS
IADKDATRAS SAYVNAEPNK KQSYDEAVQN AESIIAGLNN PTINKGNVTS ATQAVTSSKN
ALDGVERLAQ DKQTAGNSLN HLDQLTPAQQ QALENQINNA TTRDKVAEII AQAQALNEAM
KALKESIKDQ PQTEASSKFI NEDQAQKDAY TQAVQHAKDL INKTTDPTLA KSIIDQATQA
VTDAKNNLHG DQKLDQDKQR ATETLNNLSN LNTPQRQALE NQINNAATRG EVAQKLTEAE
ALNQAMEALR NSIQDQQQTE AGSKFINEDK PQKDAYQAAV QNAKDLINQT NNPTLDKAQV
EQLTQAVNQA KDNLHGDQKL ADDKQHAVTD LNQLNGLNNP QRQALESQIN NAATRDEVAQ
KLAEAKALDQ AMQALRNSIQ DQQQTESGSK FINEDKPQKD AYQAAVQNAK DLINQTGNPT
LDKSQVEQLT QAVTTAKDNL HGDQKLARDQ LQAVTTVNAL PNLNHAQQQA LTDAINAAPT
RTEVAQHVQT ATELDHAMET LKNKVDQVNT DKAQPNYTEA STDKKEAVDQ ALQAAESITD
PTNGSNANKD AVDQALTKLQ EKVNELNGNE RVAEAKTQAK QTIDQLTHLN ADQIATAKQN
IDQATKLQPI AELVDQATQL NQSMDQLQQA VNEHANVEQT VDYTQADLDK QNAYKQAIAD
AENVLKQNAN KQQVDQALQN ILNAKQALNG DERVALAKTN GKHDIEQLNA LNNAQQDGFK
GRIDQSNDLN QIQQIVDEAK ALNRVMDQLS QGITGNEGRT KGSTNYVNAD TQVKQVYDEA
VDKAKQALDK STGQNLTAEQ VIKLNDAVTA AKKALNGEEK LNNRKSEALQ RLDQLTHLNN
AQRQLAIQQI NNAETLNKAS RAINRATKLD NAMGAVQQYI DEQHLGVISS TNYINADDNL
KANYDNAIAN AAHELDKVQG NAIAKAEAEQ LKQNIIDAQN ALNGDQNLAN AKDKANAFVN
SLNGLNQQQQ HLAHNAINNA DTVSDVTDIV NNQIDLNDAM ETLKHLVDNE IPNAEQTVNY
QNAEDNAKTN FDDAKRLANT LLNSDNTNVN DINGAIQTVN DAIQNLNGDQ RLQDAKDKAI
QSINQALANK LKEIEASNAT DQDKLIAKNK AEELANSIIN NINKATSNQD VSQVQTAGNH
AIEQVHANEI PKAKIDANKD VDKQVQALID EIDRNPILTD KEKQALKDRI NQILQQGHND
INNAMTKEEI EQAKAQLGQA LQDIKDLVKA KESAKQDIDK QVQALIDEID RNPILTDKEK
QALKDRINQI LQQGHNGINN AMTKEEIEQA KAQLGQALQD IKDLVKAKES AKQDIDKQVQ
ALIDEIDRNP NLTDKEKQAL KDRINQILQQ GHNGINNAMT KEEIEHAKAQ LAQALQDIKD
LVKAKEDAKN AIKALANAKR DQINSNPDLT LEQKAKALKE IDEAEKRALE NIENAQTKDQ
LNQGLNLGLD DIRNTHVWEV DAQPAVNEIF DATPEQILVN GELIVHRDDI ITEQDILAHI
NLIDQLTAEI IDTPSTATIS DSLTAKVEVT LLDGSKVIVN VPVKVVEKEL TVVKQQAIES
IENAAQQKIN EINNHATLTP EQKEAAIAEV NKLKQQAIEQ INNAADVHTV EEVQHQEQAH
IEQFNPDQFT IDQAKSNAIK SISDAIQHMI DEINASKDLT DKEKQEAISK LNQLKDQSIQ
AIQRAQSIDE IAQQLEQFKA QLKAANPFAK ELENRKKAAI SKIKDISTDK IDRIRNSTIG
TAEERQAAMN RINEIVLETI KDINNAQTPQ QVEAALNNGI ARILAVQIVT SDHSKPSSNS
DGQSNSHLHV GYGTVNHPFN SSPIGHKKKL DQDDEIDPLH MRHFGDRIGN VIKNALGVVG
ISGLLASFWF FIAKRRRKED EEEELEIRDN SKDKKKGSIE GTKHLPLLFA KRRRKEDEED
AIVEEKDSLN NDESLDKVKH TPFFLPKRRR KEDEEDVEVT NENTDEKVLQ DNEHSPVLIA
KRLKDKDGNV ETTTSIESKD EDVPLLLAKK KNQKDNQSKG KKSASKKPSK KVAAKKKKKK
SKKNKK