EBH_STAAW
ID EBH_STAAW Reviewed; 9904 AA.
AC Q8NWQ6;
DT 02-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2002, sequence version 1.
DT 25-MAY-2022, entry version 111.
DE RecName: Full=Extracellular matrix-binding protein ebh;
DE AltName: Full=ECM-binding protein homolog;
DE Flags: Precursor;
GN Name=ebh; OrderedLocusNames=MW1324;
OS Staphylococcus aureus (strain MW2).
OC Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC Staphylococcus.
OX NCBI_TaxID=196620;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MW2;
RX PubMed=12044378; DOI=10.1016/s0140-6736(02)08713-5;
RA Baba T., Takeuchi F., Kuroda M., Yuzawa H., Aoki K., Oguchi A., Nagai Y.,
RA Iwama N., Asano K., Naimi T., Kuroda H., Cui L., Yamamoto K., Hiramatsu K.;
RT "Genome and virulence determinants of high virulence community-acquired
RT MRSA.";
RL Lancet 359:1819-1827(2002).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Single-pass membrane
CC protein {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; BA000033; BAB95189.1; -; Genomic_DNA.
DR RefSeq; WP_001109341.1; NC_003923.1.
DR PDB; 4KJM; X-ray; 2.00 A; A/B=3912-4037.
DR PDBsum; 4KJM; -.
DR SMR; Q8NWQ6; -.
DR PRIDE; Q8NWQ6; -.
DR EnsemblBacteria; BAB95189; BAB95189; BAB95189.
DR KEGG; sam:MW1324; -.
DR HOGENOM; CLU_222673_0_0_9; -.
DR OMA; NRATKEM; -.
DR EvolutionaryTrace; Q8NWQ6; -.
DR Proteomes; UP000000418; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR011439; DUF1542.
DR InterPro; IPR026361; Ebh_dom.
DR InterPro; IPR020840; Extracell_matrix-bd_GA.
DR InterPro; IPR002988; GA_module.
DR InterPro; IPR009063; Ig/albumin-bd_sf.
DR InterPro; IPR005877; YSIRK_signal_dom.
DR Pfam; PF07564; DUF1542; 7.
DR Pfam; PF01468; GA; 18.
DR Pfam; PF04650; YSIRK_signal; 1.
DR SMART; SM00844; GA; 48.
DR SUPFAM; SSF46997; SSF46997; 93.
DR TIGRFAMs; TIGR04264; hyperosmo_Ebh; 1.
DR TIGRFAMs; TIGR01168; YSIRK_signal; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Cell membrane; Membrane; Repeat; Signal; Transmembrane;
KW Transmembrane helix.
FT SIGNAL 1..39
FT /evidence="ECO:0000255"
FT CHAIN 40..9904
FT /note="Extracellular matrix-binding protein ebh"
FT /id="PRO_0000345982"
FT TRANSMEM 9710..9730
FT /note="Helical"
FT /evidence="ECO:0000255"
FT DOMAIN 2524..2580
FT /note="FIVAR 1"
FT DOMAIN 2610..2666
FT /note="FIVAR 2"
FT DOMAIN 2687..2750
FT /note="FIVAR 3"
FT DOMAIN 2780..2836
FT /note="FIVAR 4"
FT DOMAIN 2864..2919
FT /note="FIVAR 5"
FT DOMAIN 2947..3002
FT /note="FIVAR 6"
FT DOMAIN 3030..3085
FT /note="FIVAR 7"
FT DOMAIN 3154..3212
FT /note="FIVAR 8"
FT DOMAIN 3280..3339
FT /note="FIVAR 9"
FT DOMAIN 3407..3465
FT /note="FIVAR 10"
FT DOMAIN 3533..3591
FT /note="FIVAR 11"
FT DOMAIN 3659..3717
FT /note="FIVAR 12"
FT DOMAIN 3785..3843
FT /note="FIVAR 13"
FT DOMAIN 3911..3969
FT /note="FIVAR 14"
FT DOMAIN 4037..4095
FT /note="FIVAR 15"
FT DOMAIN 4160..4208
FT /note="FIVAR 16"
FT DOMAIN 4276..4334
FT /note="FIVAR 17"
FT DOMAIN 4402..4460
FT /note="FIVAR 18"
FT DOMAIN 4528..4586
FT /note="FIVAR 19"
FT DOMAIN 4654..4712
FT /note="FIVAR 20"
FT DOMAIN 4780..4838
FT /note="FIVAR 21"
FT DOMAIN 4906..4964
FT /note="FIVAR 22"
FT DOMAIN 5032..5090
FT /note="FIVAR 23"
FT DOMAIN 5158..5216
FT /note="FIVAR 24"
FT DOMAIN 5284..5342
FT /note="FIVAR 25"
FT DOMAIN 5410..5468
FT /note="FIVAR 26"
FT DOMAIN 5536..5593
FT /note="FIVAR 27"
FT DOMAIN 5661..5719
FT /note="FIVAR 28"
FT DOMAIN 5787..5845
FT /note="FIVAR 29"
FT DOMAIN 5913..5971
FT /note="FIVAR 30"
FT DOMAIN 6039..6097
FT /note="FIVAR 31"
FT DOMAIN 6175..6223
FT /note="FIVAR 32"
FT DOMAIN 6291..6349
FT /note="FIVAR 33"
FT DOMAIN 6417..6475
FT /note="FIVAR 34"
FT DOMAIN 6543..6601
FT /note="FIVAR 35"
FT DOMAIN 6669..6727
FT /note="FIVAR 36"
FT DOMAIN 6795..6853
FT /note="FIVAR 37"
FT DOMAIN 6921..6979
FT /note="FIVAR 38"
FT DOMAIN 7047..7105
FT /note="FIVAR 39"
FT DOMAIN 7173..7231
FT /note="FIVAR 40"
FT DOMAIN 7299..7357
FT /note="FIVAR 41"
FT DOMAIN 7425..7486
FT /note="FIVAR 42"
FT DOMAIN 7551..7609
FT /note="FIVAR 43"
FT DOMAIN 7677..7735
FT /note="FIVAR 44"
FT DOMAIN 7803..7860
FT /note="FIVAR 45"
FT DOMAIN 7928..7986
FT /note="FIVAR 46"
FT DOMAIN 8054..8112
FT /note="FIVAR 47"
FT DOMAIN 8180..8238
FT /note="FIVAR 48"
FT DOMAIN 8306..8364
FT /note="FIVAR 49"
FT DOMAIN 8432..8490
FT /note="FIVAR 50"
FT DOMAIN 8558..8612
FT /note="FIVAR 51"
FT DOMAIN 8680..8739
FT /note="FIVAR 52"
FT DOMAIN 8934..8990
FT /note="FIVAR 53"
FT REGION 41..153
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 250..277
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 9807..9904
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 41..125
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 126..141
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 9807..9885
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 9886..9904
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT HELIX 3912..3919
FT /evidence="ECO:0007829|PDB:4KJM"
FT HELIX 3922..3926
FT /evidence="ECO:0007829|PDB:4KJM"
FT HELIX 3929..3932
FT /evidence="ECO:0007829|PDB:4KJM"
FT HELIX 3936..3952
FT /evidence="ECO:0007829|PDB:4KJM"
FT HELIX 3963..3979
FT /evidence="ECO:0007829|PDB:4KJM"
FT HELIX 3982..3998
FT /evidence="ECO:0007829|PDB:4KJM"
FT HELIX 4005..4016
FT /evidence="ECO:0007829|PDB:4KJM"
FT HELIX 4021..4035
FT /evidence="ECO:0007829|PDB:4KJM"
SQ SEQUENCE 9904 AA; 1068495 MW; CE86908F75EA56B2 CRC64;
MNYRDKIQKF SIRKYTVGTF STVIATLVFL GFNTSQAHAA ETNQPASVVK QKQQSNNEQT
ENRESQVQNS QNSQNSQSLS ATHENEQPNI SQANLVDQKV AQSSTTNDEQ PASQNVNTKK
DSATAATTQP DKEEGKHKQN ESQSANKNGN DNRAAHLENH EANVVTASDS SDNGNVQHDR
NELQAFFDAN YHDYRFIDRE NADSGTFNYV KGIFEKINTL LGSNDPINNK DLQLAYKELE
QAVALIRTMP QRQQTSRRSN RIQTRSVESR AAEPRSVSDY QNANSSYYVE NANDGSGYPV
GTYINASSKG APYNLPTTPW NTLKASDSKE IALMTAKQTG DGYQWVIKFN KGHAPHQNMI
FWFALPADQV PVGRTDFVTV NSDGTNVQWS HGAGAGANKP LQQMWEYGVN DPDRSHDFKI
RNRSGQVIYS WPTVHVYSLE DLSRASDYFS EAGATAATKA FGRQNFEYIN GQKPAESPGV
PKVYTFIGQG DASYTISFKT QGPTVNKLYY AAGGRALEYN QLFMYSQLYV ESTQDHQQRL
NGLRQVVNRT YRIGTTKRVE VSQGNVQTKK VLESTNLNID GFVDDPLSYV KTPSNKVLGF
YPTNATTNAF RPGGVQELNE YQLSQLFTDQ KLQEAARTRN PIRLMIGFDY PDGYGNSETL
VPVNLTVLPE IQHNIKFFKN DDTQNIAEKP FSKQAGHPVF YVYAGNQGNA SVNLGGSVTS
IQPLRINLTS NENFTDKDWQ ITGIPRTLHI ENSTNRTNNA RERNIELVGN LLPGDYFGTI
RFGRKEQLFE IRVKPHTPTI TTTAEQLRGT ALQKVPVNIS GIPLDPSALV YLVAPTNQTT
NGGSEADQIP SGYTILATGT PDGVHNTITI RPQDYVVFIP PVGKQIRAVV YYNKVVASNM
SNAVTILPDD IPPTINNPVG INAKYYRGDE VNFTMGVSDR HSGIKNTTIT TLPNGWTSNL
TKSDNKNGSL AITGRVSMNQ AFNSDITFKV SATDNVNNTT NDSQSKHVSI HVGKISEDAH
PIVLGNTEKV VVVNPTAVSN DEKQSIITAF MNKNQNIRGY LASTDPVTVD NNGNVTLHYR
DGSSTTLDAT NVMTYEPVVK SEYQTANAAK TATVTIAKGQ SFNIGDIKQY FTLSNGQAIP
SGTFTNITSD RTILTAQEVS QMNAGTQLYH IVASNAYHKD TEDFYISLKI VDVKQPEGDQ
RVYRTSTYDL TTDEISKVKQ AFINANRDVI TLAEGNISVT NTPNGANVST ITVNINKGRL
TKSFASNLAN MNFLRWVNFP QDYTVTWTNA KIANRPTDGG LSWSDDHKSL IYRYDATLGT
QITTNDILTM LKATTTVPGL RNNITGNEKA QAEAGGRPNF RTTGYSQSNA TTDGQRQFTL
NGQVIQVLDI INPSNGYGGQ PVTNSNTRAN HSNSTVVNVN EPAANGASAF TIDHVVKSNS
THNASDAVYK AQLYLTPYGP KQYVEHLNQN TGNTTDAINI YFVPSDLVNP TISVGNYTNH
QVFSGETFTN TITANDNFGV QSVTVPNTSQ ITGTVDNNHQ HVSATAPNVT SATNKTINLL
ATDTSGNTAT TSFNVTVKPL RDKYRVGTSS TAANPVRIAN ISNNATVSQA DQTAIINSLT
FTETVPNRSY ARASANEITS KTVSNVSRTG NNANVTVTAT YQDGTTSTVT VPVKHVIPEI
VAHSHYTVQG QDFPAGNGSS ASDYFKLSNG SAIPDATITW VSGQAPNKDN TRIGEDITVT
AHILIDGETT PITKTATYKV VSTVPKHVFE TNRGAVFPGV SDVYDAKQYV KPVNDSWTQN
AQRMNFQFTN SYGPSKDVVG ISTRDIRVTY DNHQTQIIKI LAKVKPDPPR IDGNSVTYKA
GLTNQQIKIN NVLSSSSIKL FKADNTPLTI TNTTYGSGNT AVVTVSDALP NGVIKARSSI
TMNNVTYTTQ DEHGRAIDVT RNESVDSNDS ATVTVTPQLQ ATTEGAVFIK GGDGFDFGHV
ERFIQNPPHG ATVAWHDSPD TWKNTVGNTH KTAVVTLPNG QGTRNVEVPV KVYPVANAKA
PSRDVKGQNL TNGTDAMNYI TFDPNTNTNG ITAAWANRQQ PNNQQAGVQH LNVDVTYPGI
SAAKRVPVTV NVYQFEFPQT TYTTTVGGTL ASGTQASGYA HMQNATGLPT DGFTYKWNRD
TTGTNDANWS AMNKPNVAKV VNAKYDVIYN GHTFATSLPA KFVVKDVQPA KPTVTETAAG
AITIAPGANQ TVNTHAGNVT TYADKLVIKR NGNVVTTFTR RNNTSPWVKE ASAATVAGIA
GTNNGITVAA GTFNPADTIQ VVATQGSGET VSDEQRSDDF TVVAPQPNQA TTKIWQNGHI
DITPNNPSGH LINPTQAMDI AYTEKVGNGA EHSKTINVVR GQNNQWTIAN KPDYVTLDAQ
TGKVTFNANT IKPNSSITIT PKAGTGHSVS SNPSTLTAPA AHTVNTTEIV KDYGSNVTAA
EINNAVQVAN KRTATIKNGT AMPTNLAGGS TTTIPVTVTY NDGSTEEVQE SIFTKADKRE
LITAKNHLDD PVSTEGKKPG TITQYNNAIH NAQQQINTAK TEAQQVINND RATPQQVSDA
LTKVRAAQTK IDQAKALLQN KEDNSQLVTS KNNLQSSVNQ VPSTAGMTQQ SIDNYNAKKR
EAETEITAAQ RVIDNGDATP QQISEEKHRV DNALTALNQA KQNLTADTHT LEQAVQQLNR
TGTTTGKKPA SITAYNNSMH ALQAELTSAK NSANAIIQKP IRSVQEVQTA LTNVNRVNER
LTQAINQLVP LADNSALRTA KTKLDEEINK SVTTDGMTQS SIQAYENAKR AGQTESTNAQ
NVINNGDATD QQIAEEKTKV EEKYNSLKQA IAGLTPDLAP LQTAKTQLQN DIDQPTSTTG
MTSTSIAAFN EKLSAARTKI QEIDRVLASH PDVATIRQNV TAANAAKTAL DQARNGLTVD
KAPLENAKNQ LQHSIDTQTS TTGMTQDSIN AYNAKLTAAR NKIQQINQVL AGSPTVEQIN
TNTSAANQAK SDLDHARQAL TPDKAPLQTA KTQLEQSINQ PTDTTGMTTA SLNAYNQKLQ
AARQKLTEIN QVLNGNPTVQ NINDKVTEAN QAKDQLNTAR QGLTLDRQPA LTTLHGASNL
NQAQQNNFTQ QINAAQNHAA LETIKSNITA LNTAMTKLKD SVADNNTIKS GQNYTDATPA
NKQAYDNAVN AAKGVIGETT NPTMDVNTVN QKAASVKSTK DALDGQQNLQ RAKTEATNAI
THASDLNQAQ KNALTQQVNS AQNVHAVNDI KQTTQSLNTA MTGLKRGVAN HNQVVQSDNY
VNADTNKKND YNNAYNHAND IINGNAQHPV ITPSDVNNAL SNVTSKEHAL NGEAKLNAAK
QEANTALGQL NNLNNAQRQN LQSQINSAHQ IETVNTIKQN ATNLNSAMGN LRQAVADKDQ
VKRTEDYADA DTAKQNAYNS AVSSAETIIN QTTNPTMSVD DVNRATSAVT SNKNALNGDE
KLAQSKTDAA RAIDALPHLN NAQKADVKSK INAASNIAGV NTVKQQGTDL NTAMGNLQGA
INDEQTTLNS QNYQDATPSK KTAYTNAVQA AKDILNKSNG QNKTKDQVTE AMNQLNSAKN
NLDGTRLLDQ AKQTAKQQLN NMTHLTTAQK TNLTNQINSG TTVAGVHTVQ SNANTLDQAM
NTLRQSIANK DATKASEDYV DANNDKQTAY NNAVAAAETI INANSNPEMN PSTITQKAEQ
VNSSKTALNG DENLATAKQN AKTYLNTLTS ITDAQKNNLI SQISSATRVS GVDTVKQNAQ
HLDQAMASLQ SGINNESQVK SSEKYRDADT NKQQEYDNAI TAAKAILNKQ HGPNTAQNAV
EAALQRVNTA KDALNGDAKL IAAQNAAKQH LGTLTHITTA QRNDLTNQIS QATNLAGVES
VKQNANSLDG AMGNLQTAIN DKSGTLASQN FLDADEQKRN AYNQAVSAAE TILNKQTGPN
TAKTAVEQAL NNVNNAKHAL NGTQNLNNAK QAAITAINGA SDLNQHQKDA LKAQANGAQR
VSNAQDVQRN ATELNTAMGT LKHAIADKTN TLASSKYVNA DSTKQNAYTT KVTNAEHIIS
GTPTVVTTPS EVTAAANQVN SAKQELNGDE RLRVAKQNAN TAIDALTQLN TPQKAKLKEQ
VGQANTLDDA MNSLQGAIND KDATLRNQNY LDADESKRNA YTQAVTAAEG ILNKQTGGNT
SKADVDNALN AVTRAKAALN GAENLRNAKT SATNTINGLP NLTQLQKDNL KHQVEQAQNV
AGVNGVKDKG NTLNTAMGAL RTSIQNDNTT KTSQNYLDAS DSNKNNYNTA VNNANGVINA
TNNPNMDANA INGMANQVNT TKAALNGVQN LAQAKTNATN TINNAHDLNQ KQKDALKTQV
NNAQRVSDAN NVQHTATELN GAMTALKAAI ADKERTKASG NYVNADQEKR QAYDSKVTNA
ENIINGTPNA TLTVNDVNSA TSQVNAAKTA LNGDNNLRVA KENANNTIDG LAQLNNAQKA
KLKEQVQSAT TLEGVQTVKN SSQTLNTAMK GLRDSIANEA TIKAGQNYTD ASPTNRNEYD
SAVTAAKAII NQTSNPTMEP NTITQATSQV TTKEHALNGA QNLAQAKTTA KNNLNNLTSI
NNAQKDALTR SIDGATTVAG VNQETAKATE LNNAMHSLQN GINDETQTKQ TQKYLDAEPN
KKSAYDQAVN AAKAILTKAS GQNVDKAAVE QALQNVNSTK TALNGDAKLN EAKAAAKQTL
GTLTHINNAQ RNALDNEITQ ATNVEGVNTV KAKAQQLDGA MGQLETSIRD KDTTLQSQNY
QDADDAKRTA YSQAVNAAAT ILNKTAGGNT PKADVERAMQ AVAQANTALN GIQNLERAKQ
AANTAITNAS DLNTKQKEAL KAQVTSAGRV SAANGVEHTA TEINTAMTAL KRAIADKADT
KTSGNYVNAD ANKRQAYDEK VTAAESIVNG TPTPTLTPSD VTNAATQVTN AKTQLNGNHN
LEVAKQNANT AIDGLTSLNG PQKAKLKEQV GQATTLPNVQ TVRDNAQTLN TAMKGLRDSI
ANEATIKAGQ NYTDASPNNR SEYDSAVTAA KAIIGQTTSP SMNAQEINQA KDQVTAKQQA
LNGQENLRTA QTNAKQHLNG LSDLTNAQKE AAKRQIEGAT HVNEVTQAQN NADALNTAMT
NLKNGIQDQN TIKQGVNFTD ADEAKRNAYT NAVTQAEQIL NKAQGPNTAK DNVESALQNV
QRAKNELNGN QNVANAKTTA KNALNNLTSI NNAQKEALKS QIEGATTVAG VNQVSTTASE
LNTAMSNLQR GINDEAATKA AQKYTDADRD KQTAYNDAVT AAKTLLDKTA GTNENKAAVE
QALQRVNTAK TALNGDARLN EAKNTAKQQV ATMSHLTDAQ KANLTSQIES GTTVAGVQGI
QANAGTLDQA MNQLRQSIAS KDATKSSEDY QDANADLQNA YNDAVTNAEG IISATNNPEM
NPDTINQKAS QVNSAKSALN GDEKLAAAKQ TAKSDIGRLT DLNNAQRTAA NAEVDQAPNL
AAVTAAKNKA TSLNTAMGNL KHALAEKDNT KRSVNYTDAD QPKQQAYDTA VTQAEAITNA
NGSNANETTV QAALNQLNQA KNDLNGDNKV AQAKESAKRA LASYSNLNNA QSTAATSQID
NATTVAGVTA AQNTANELNT AMGQLQNGIN DQNTVKQQVN FTDADQGKKD AYTNAVTNAQ
GILDKANGQN MTKAQVEAAL NQVTTAKNAL NGDANVRQAK SDAKANLGTL THLNNAQKQD
LTSQIEGATT VNGVNSVKTK AQDLDGAMQR LESAIANKDQ TKASENYIDA DPTKKTAFDN
AITQAESYLN KDHGTNKDKQ AVEQAIQSVT STENALNGDA NLQRAKTEAT QAIDNLTHLN
TPQKTALKQQ VNAAQRVSGV TDLKNSATSL DNAMDQLKQG IADHDTIVAG GNYTNASPDK
QGAYTDAYNA AKNIVNGSPN VITNAADVTA ATQRVNNAET SLNGDSNLAT AKQQAKDALR
QMTHLSDAQK QSITGQIDSA TQVTGVQSVK DNATNLDNAM NQLRNSIANK DEVKASQPYV
DADTDKQNAY NTAVTSAENI INATSQPTLD PSAVTQAANQ VNTNKTALNG AQNLANKKQE
TTANINQLSH LNNAQKQDLN TQVTNAPNIS TVNQVKTKAE QLDQAMERLI NGIQDKDQVK
QSVNFTDADP EKQTAYNNAV TAAENIINQA NGTNANQSQV EAALSTVTTT KQALNGDRKV
TDAKNNANQT LSTLDNLNNA QKGAVTGNIN QAHTVAEVTQ AIQTAQELNT AMGNLKNSLN
DKDTTLGSQN FADADPEKKN AYNEAVRNAE NILNKSTGTN VPKDQVEAAM NQVNTTKAAL
NGTQNLEKAK QHANTAIDGL SHLTNAQKEA LKQLVQQSTT VAEAQGNEQK ANNVDAAMDK
LRQSIADNAT TKQNQNYTDA SPNKKDAYNN AVTTAQGIID QTTSPTLDPT VINQAAGQVS
TTKNALNSNE NLEAAKQQAT QSLGSLDNLN NAQKQAVTDQ INGAHTVDEA NQIKQNAQNL
NTAMGNLKQA IADKDATKAT VNFTDADQAK QQAYNTAVTN AENIISKANG GNATQTEVEQ
AIQQVNAAKQ ALNGNANVQH AKDEATALIN SSNDLNQAQK NALKQQVQNA TTVAGVNNVK
QTAQELNNAM TQLKQGIADK EQTKADGNFV NADPDKQNAY NQAVAKAEAL ISGTPDVVVT
PSEITAALNK VTQAKNDLNG NTNLATAKQN VQHAIDQLPN LNQAQRDEYN KQITQATHVP
NVNAIQQAAT TLNDAMTQLK QGIANKAQIK GSENYHDADT DKQTAYDNAV TKAEELLKQT
TNPTMDPNTI QQALTKVNDT NQALNGNQKL ADAKQAAKTN LGTLDHLNDA QKQALTTQVE
QAPDIATVNN VKQNAQNLNN AMTNLNNALQ DKTETLNSIN FTDADQAKKD AYTNAVSHAE
GILSKANGSN ASQTEVEQAM QRVNEAKQAL NGNDNVQRAK DAAKQVITNA NDLNQAQKDA
LKQQVDAAQT VANVNTIKQT AQDLNQAMTQ LKQGIADKDQ TKANGNFVNA DTDKQNAYNN
AVAHAEQIIS GTPNANVDPQ QVAQALQQVN QAKGDLNGNH NLQVAKDNAN TAIDQLPNLN
QPQKTALKDQ VSHAELVTGV NAIKQNADAL NNAMGTLKQQ IQANSQVPQS VDFTQADQDK
QQAYNNAANQ AQQIANGTPT PVLAPDTVTQ AVTTMNQAKD ALNGDEKLAQ AKQDALANLD
TLRDLNQPQR DALRNQINQA QALATVEQTK QNAQNVNTAM GNLKQGIANK DTVKASENYH
DADVDKQTAY TNAVSQAEGI INQTTNPTLN PDDITRALTQ VTDAKNSLNG EAKLATEKQN
AKDAVNAMTH LNDAQKQALK GQIDQSPEIA TVNQVKQTAT SLDHAMDQLS QAINDKAQTL
ADGNYLNADP DKQNAYKQAV AKAEALLNKQ SGTNEVQAQV ESITNEVNAA KQALNGNDNL
ANAKQQAKQQ LANLTHLNDA QKQSFESQIT QAPLVTDVTT INQKAQTLDH AMELLRNSVA
DNQTTLASED YHDATAQRQN DYNQAVTAAN NIINQTTSPT MNPDDVNGAT TQVNNTKVAL
DGDENLAAAK QQANNRLDQL DHLNNAQKQQ LQSQITQSSD IAAVNGHKQT AETLNTAMGN
LINAIADHQA VEQRGNFINA DTDKQTAYNT AVNEAAAMIN KQTGQNANQT EVEQAITKVQ
TTLQALNGDH NLQVAKTNAT QAIDALTSLN DPQKTALKDQ VTAATLVTAV HQIEQNANTL
NQAMHGLRQS IQDNAATKAN SKYINEDQPE KQNYDQAVQA ANNIINEQTA TLDNNAINQA
AATVNTTKAA LHGDVKLQND KDHAKQTVSQ LAHLNNAQKH MEDTLIDSET TRTAVKQDLT
EAQALDQLMD ALQQSIADKD ATRASSAYVN AEPNKKQAYD EAVQNAESII AGLNNPTINK
GNVSSATQAV TSSKNALDGV ERLAQDKQTA GNSLNHLDQL TPAQQQALEN QINNATTRDK
VAEIIAQAQA LNEAIKALKE SIKDQPQTEA SSKFINEDQA QKDAYTQAVQ HAKDLINKTT
DPTLAKSIID QATQAVTDAK NNLHGDQKLA QDKQRATETL NNLSNLNTPQ RQALENQINN
AATRVEVAQK LTEAQALNQA MEALRNSIQD QQQTEAGSKF INEDKPQKDA YQAAVQNAKD
LINQTNNPTL DKAQVEQLTQ AVNQAKDNLH GDQKLADDKQ HAVTDLNQLN GLNNPQRQAL
ESQINNAATR DEVAQKLAEA KALDQAMQAL RNSIQDQQQT ESGSKFINED KPQKDAYQAA
VQNAKDLINQ TGNPTLDKAQ VEQLTQAVTT AKDNLHGDQK LARDQQQAVT TVNALPNINH
AQQQALTDAI NAAPTRTEVA QHVQTATELD HAMETLKNKV DQVNTDKAQP NYTEASTDKK
EAVDQALQAA ESITDPTNGS NANKDAVEQA LTKLQEKVNE LNGDERVAEA KTQAKQNIDQ
LTHLNADQIA TAKQNIDQAT QLQPIAELVD QATQLNQSMD QLQQAVNDHT NVEQTVDYTQ
ADSDKQKAYK QAIADAENVL KQNANKQQVD QALQNILNAK QALNGDERVA LAKTNGKHDI
DQLNALNNAQ QDGFKGRIDQ SNDLNQIQQI VDEAKALNRA MDQLSEEITG NEGRTKGSTN
YVNADTQVKQ VYDEAVDKAK QALDKSTGQN LTAEQVIKLN DAVTAAKQAL NGEERLNNRK
SEALQRLDQL THLNNAQRQL AIQQINNAET LNKASRAINR ATKLDNAMGA VQQYIDEQHL
GVISSTNYIN ADDNLKANYD NAIANAAHEL DKVQGNAIAK AEAEQLKQNI IDAQNALNGD
QNLANAKDKA NAFVNSLNGL NQQQQDLAHK AINNADTVSD VTDIVNNQID LNDAMETLKH
LVDNEIPNAE QTVNYQNADD NAKTNFDDAK RLANALLNSD NTNVNDINGA IQAVNDAIHN
LNGDQRLQDA KDKAIQSINQ ALANKLKEIE ASNATDQDKL IAKNKAEELA NSIINNINKA
TSNQDVSQVQ TAGNHAIEQV HANEIPKAKI DANKDVDKQV QALIDEIDRN PNLTDKEKQA
LKDRINQILQ QGHNDINNAL TKEEIEQAKA QLAQALQEIK DLVKAKENAK QDVDKQVQAL
IDEIDQNPNL TDKEKQALKD RINQILQQGH NDINNAMTKE EIEQAKAQLA QALQDIKDLV
KAKEDAKNAI KALANAKRDQ INSNPDLTPE QKAKALKEID EAEKRALQNV ENAQTIDQLN
RGLNLGLDDI RNTHVWEVDE QPAVNEIFEA TPEQILVNGE LIVHRDDIIT EQDILAHINL
IDQLSAEVID TPSTATISDS LTAKVEVTLL DGSKVIVNVP VKVVEKELSV VKQQAIESIE
NAAQQKINEI NNSVTLTLEQ KEAAIAEVNK LKQQAIDHIN NAPDVHSVEE IQQQEQAHIE
QFNPEQFTIE QAKSNAIKSI EDAIQHMIDE IKARTDLTDK EKQEAIAKLN QLKEQAIQAI
QRAQSIDEIT EQLEQFKAQM KAANPTAKEL AKRKQEAISR IKDFSNEKMN SIRNSEIGTA
DEKQAAMNQI NEIVLETIRD INNAHTLQQV EAALNNGIAR ISAVQIVISD RAKQSSSTGN
ESNSHLTIGY GTANHPFNSS TIGHKKKIDE DDDIDPLHMR HFSNNFGNVI KNAIGVVGIS
GLLASFWFFI AKRRRKEDEE EELEIRDNNK DSIKETLDDT KHLPLLFAKR RRKEDEEDVT
VEEKDSLNNG ESLDKVKHTP FFLPKRRRKE DEEDVEVTNE NTDEKVLKDN EHSPLLFAKR
RKDKEEDVET TTSIESKDED VPLLLAKKKN QKDNQSKDKK SASKNTSKKV AAKKKKKKSK
KNKK
