EBH_STAES
ID EBH_STAES Reviewed; 9439 AA.
AC Q8CP76;
DT 02-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2003, sequence version 1.
DT 25-MAY-2022, entry version 111.
DE RecName: Full=Extracellular matrix-binding protein ebh;
DE AltName: Full=ECM-binding protein homolog;
GN Name=ebh; OrderedLocusNames=SE_1128;
OS Staphylococcus epidermidis (strain ATCC 12228 / FDA PCI 1200).
OC Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC Staphylococcus.
OX NCBI_TaxID=176280;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 12228 / FDA PCI 1200;
RX PubMed=12950922; DOI=10.1046/j.1365-2958.2003.03671.x;
RA Zhang Y.-Q., Ren S.-X., Li H.-L., Wang Y.-X., Fu G., Yang J., Qin Z.-Q.,
RA Miao Y.-G., Wang W.-Y., Chen R.-S., Shen Y., Chen Z., Yuan Z.-H.,
RA Zhao G.-P., Qu D., Danchin A., Wen Y.-M.;
RT "Genome-based analysis of virulence genes in a non-biofilm-forming
RT Staphylococcus epidermidis strain (ATCC 12228).";
RL Mol. Microbiol. 49:1577-1593(2003).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Single-pass membrane
CC protein {ECO:0000305}.
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DR EMBL; AE015929; AAO04725.1; -; Genomic_DNA.
DR RefSeq; NP_764683.1; NC_004461.1.
DR RefSeq; WP_011082687.1; NZ_WBME01000002.1.
DR SMR; Q8CP76; -.
DR STRING; 176280.SE_1128; -.
DR EnsemblBacteria; AAO04725; AAO04725; SE_1128.
DR KEGG; sep:SE_1128; -.
DR PATRIC; fig|176280.10.peg.1101; -.
DR eggNOG; COG1196; Bacteria.
DR eggNOG; COG1511; Bacteria.
DR eggNOG; COG4372; Bacteria.
DR HOGENOM; CLU_222673_0_0_9; -.
DR OMA; NRATKEM; -.
DR Proteomes; UP000001411; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR044024; aRib.
DR InterPro; IPR011439; DUF1542.
DR InterPro; IPR026361; Ebh_dom.
DR InterPro; IPR020840; Extracell_matrix-bd_GA.
DR InterPro; IPR002988; GA_module.
DR InterPro; IPR009063; Ig/albumin-bd_sf.
DR Pfam; PF18938; aRib; 1.
DR Pfam; PF07564; DUF1542; 5.
DR Pfam; PF01468; GA; 29.
DR SMART; SM00844; GA; 39.
DR SUPFAM; SSF46997; SSF46997; 74.
DR TIGRFAMs; TIGR04264; hyperosmo_Ebh; 1.
PE 4: Predicted;
KW Cell membrane; Membrane; Repeat; Transmembrane; Transmembrane helix.
FT CHAIN 1..9439
FT /note="Extracellular matrix-binding protein ebh"
FT /id="PRO_0000345984"
FT TRANSMEM 9306..9324
FT /note="Helical"
FT /evidence="ECO:0000255"
FT DOMAIN 1815..1871
FT /note="FIVAR 1"
FT DOMAIN 1901..1957
FT /note="FIVAR 2"
FT DOMAIN 1985..2041
FT /note="FIVAR 3"
FT DOMAIN 2071..2127
FT /note="FIVAR 4"
FT DOMAIN 2155..2211
FT /note="FIVAR 5"
FT DOMAIN 2241..2297
FT /note="FIVAR 6"
FT DOMAIN 2325..2381
FT /note="FIVAR 7"
FT DOMAIN 2411..2467
FT /note="FIVAR 8"
FT DOMAIN 2488..2551
FT /note="FIVAR 9"
FT DOMAIN 2581..2638
FT /note="FIVAR 10"
FT DOMAIN 2665..2720
FT /note="FIVAR 11"
FT DOMAIN 2748..2804
FT /note="FIVAR 12"
FT DOMAIN 2832..2888
FT /note="FIVAR 13"
FT DOMAIN 2918..2974
FT /note="FIVAR 14"
FT DOMAIN 3002..3058
FT /note="FIVAR 15"
FT DOMAIN 3088..3144
FT /note="FIVAR 16"
FT DOMAIN 3172..3228
FT /note="FIVAR 17"
FT DOMAIN 3258..3314
FT /note="FIVAR 18"
FT DOMAIN 3335..3398
FT /note="FIVAR 19"
FT DOMAIN 3428..3484
FT /note="FIVAR 20"
FT DOMAIN 3512..3567
FT /note="FIVAR 21"
FT DOMAIN 3595..3650
FT /note="FIVAR 22"
FT DOMAIN 3678..3733
FT /note="FIVAR 23"
FT DOMAIN 3802..3860
FT /note="FIVAR 24"
FT DOMAIN 3928..3983
FT /note="FIVAR 25"
FT DOMAIN 4056..4114
FT /note="FIVAR 26"
FT DOMAIN 4182..4240
FT /note="FIVAR 27"
FT DOMAIN 4308..4365
FT /note="FIVAR 28"
FT DOMAIN 4433..4491
FT /note="FIVAR 29"
FT DOMAIN 4559..4617
FT /note="FIVAR 30"
FT DOMAIN 4685..4743
FT /note="FIVAR 31"
FT DOMAIN 4811..4869
FT /note="FIVAR 32"
FT DOMAIN 4937..4995
FT /note="FIVAR 33"
FT DOMAIN 5063..5115
FT /note="FIVAR 34"
FT DOMAIN 5189..5246
FT /note="FIVAR 35"
FT DOMAIN 5314..5372
FT /note="FIVAR 36"
FT DOMAIN 5440..5498
FT /note="FIVAR 37"
FT DOMAIN 5566..5624
FT /note="FIVAR 38"
FT DOMAIN 5692..5750
FT /note="FIVAR 39"
FT DOMAIN 5818..5875
FT /note="FIVAR 40"
FT DOMAIN 5943..6000
FT /note="FIVAR 41"
FT DOMAIN 6068..6126
FT /note="FIVAR 42"
FT DOMAIN 6194..6252
FT /note="FIVAR 43"
FT DOMAIN 6320..6378
FT /note="FIVAR 44"
FT DOMAIN 6446..6504
FT /note="FIVAR 45"
FT DOMAIN 6572..6630
FT /note="FIVAR 46"
FT DOMAIN 6698..6755
FT /note="FIVAR 47"
FT DOMAIN 6823..6877
FT /note="FIVAR 48"
FT DOMAIN 6949..7007
FT /note="FIVAR 49"
FT DOMAIN 7075..7133
FT /note="FIVAR 50"
FT DOMAIN 7201..7259
FT /note="FIVAR 51"
FT DOMAIN 7327..7384
FT /note="FIVAR 52"
FT DOMAIN 7452..7510
FT /note="FIVAR 53"
FT DOMAIN 7578..7636
FT /note="FIVAR 54"
FT DOMAIN 7704..7762
FT /note="FIVAR 55"
FT DOMAIN 7830..7888
FT /note="FIVAR 56"
FT DOMAIN 7956..8010
FT /note="FIVAR 57"
FT DOMAIN 8078..8137
FT /note="FIVAR 58"
FT DOMAIN 8205..8264
FT /note="FIVAR 59"
FT DOMAIN 8332..8391
FT /note="FIVAR 60"
FT DOMAIN 8459..8518
FT /note="FIVAR 61"
FT DOMAIN 8587..8643
FT /note="FIVAR 62"
FT REGION 2495..2514
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2925..2951
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 4649..4674
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 5699..5719
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 6413..6434
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 9363..9439
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 5699..5717
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 9363..9414
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 9415..9439
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 9439 AA; 1050782 MW; 5A8C68E9AA31CDD4 CRC64;
MSGTLHNTVG SGILPYQQEI RIKLTSNEPI KDSEWSITGY PNTLTLQNAV GRTNNATEKN
LALVGHIDPG NYFITVKFGD KVEQFEIRSK PTPPRIITTA NELRGNPNHK PEIRVTDIPN
DTTAKIKLVM GGTDGDHDPE INPYTVPENY TVVAEAYHDN DPSKNGVLTF RSSDYLKDLP
LSGELKAIVY YNQYVQSNFS KSVPFSSDTT PPTINEPAGL VHKYYRGDHV EITLPVTDNT
GGSGLRDVNV NLPQGWTKTF TINPNNNTEG TLKLIGNIPS NEAYNTTYHF NITATDNSGN
TTNPAKTFIL NVGKLADDLN PVGLSRDQLQ LVTDPSSLSN SEREEVKRKI SEANANIRSY
LLQNNPILAG VNGDVTFYYR DGSVDVIDAE NVITYEPERK SIFSENGNTN KKEAVITIAR
GQNYTIGPNL RKYFSLSNGS DLPNRDFTSI SAIGSLPSSS EISRLNVGNY NYRVNAKNAY
HKTQQELNLK LKIVEVNAPT GNNRVYRVST YNLTNDEINK IKQAFKAANS GLNLNDNDIT
VSNNFDHRNV SSVTVTIRKG DLIKEFSSNL NNMNFLRWVN IRDDYTISWT SSKIQGRNTD
GGLEWSPDHK SLIYKYDATL GRQINTNDVL TLLQATAKNS NLRSNINSNE KQLAERGSNG
YSKSIIRDDG EKSYLLNSNP IQVLDLVEPD NGYGGRQVSH SNVIYNEKNS SIVNGQVPEA
NGASAFNIDK VVKANAANNG IMGVIYKAQL YLAPYSPKGY IEKLGQNLSN TNNVINVYFV
PSDKVNPSIT VGNYDHHTVY SGETFKNTIN VNDNYGLNTV ASTSDSAITM TRNNNELVGQ
APNVTNSINK IVKVKATDKS GNESIVSFTV NIKPLNEKYR ITTSSSNQTP VRISNIQNNA
NLSIEDQNRV KSSLSMTKIL GTRNYVNESN NDVRSQVVSK VNRSGNNATV NVTTTFSDGT
TNTITVPVKH VLLEVVPTTR TTVRGQQFPT GKGTSPNDFF SLRTGGPVDA RIVWVNNQGP
DINSNQIGRD LTLHAEIFFD GETTPIRKDT TYKLSQSIPK QIYETTINGR FNSSGDAYPG
NFVQAVNQYW PEHMDFRWAQ GSGTPSSRNA GSFTKTVTVV YQNGQTENVN VLFKVKPNKP
VIDSNSVISK GQLNGQQILV RNVPQNAQVT LYQSNGTVIP NTNTTIDSNG IATVTIQGTL
PTGNITAKTS MTNNVTYTKQ NSSGIASNTT EDISVFSENS DQVNVTAGMQ AKNDGIKIIK
GTNYNFNDFN SFISNIPAHS TLTWNEEPNS WKNNIGTTTK TVTVTLPNHQ GTRTVDIPIT
IYPTVTAKNP VRDQKGRNLT NGTDVYNYII FENNNRLGGT ASWKDNRQPD KNIAGVQNLI
ALVNYPGIST PLEVPVKVWV YNFDFTQPIY KIQVGDTFPK GTWAGYYKHL ENGEGLPIDG
WKFYWNQQST GTTSDQWQSL AYTRTPFVKT GTYDVVNPSN WGVWQTSQSA KFIVTNAKPN
QPTITQSKTG DVTVTPGAVR NILISGTNDY IQASADKIVI NKNGNKLTTF VKNNDGRWTV
ETGSPDINGI GPTNNGTAIS LSRLAVRPGD SIEAIATEGS GETISTSATS EIYIVKAPQP
EQVATHTYDN GTFDILPDNS RNSLNPTERV EINYTEKLNG NETQKSFTIT KNNNGKWTIN
NKPNYVEFNQ DNGKVVFSAN TIKPNSQITI TPKAGQGNTE NTNPTVIQAP AQHTLTINEI
VKEQGQNVTN DDINNAVQVP NKNRVAIKQG NALPTNLAGG STSHIPVVIY YSDGSSEEAT
ETVRTKVNKT ELINARRRLD EEISKENKTP SSIRNFDQAM NRAQSQINTA KSDADQVIGT
EFATPQQVNS ALSKVQAAQN KINEAKALLQ NKADNSQLVR AKEQLQQSIQ PAASTDGMTQ
DSTRNYNNKR QAAEQAIQHA NSVINNGDAT SQQINDAKNT VEQAQRDYVE AKSNLRADKS
QLQSAYDTLN RDVLTNDKKP ASVRRYNEAI SNIRKELDTA KADASSTLRN TNPSVEQVRD
ALNKINTVQP KVNQAIALLQ PKENNSELVQ AKKRLQDAVN DIPQTQGMTQ QTINNYNDKQ
REAERALTSA QRVIDNGDAT TQEITSEKSK VEQAMQALTN AKSNLRADKN ELQTAYNKLI
ENVSTNGKKP ASIRQYETAK ARIQNQINDA KNEAERILGN DNPQVSQVTQ ALNKIKAIQP
KLTEAINMLQ NKENNTELVN AKNRLENAVN DTDPTHGMTQ ETINNYNAKK REAQNEIQKA
NMIINNGDAT AQDISSEKSK VEQVLQALQN AKNDLRADKR ELQTAYNKLI QNVNTNGKKP
SSIQNYKSAR RNIENQYNTA KNEAHNVLEN TNPTVNAVED ALRKINAIQP EVTKAINILQ
DKEDNSELVR AKEKLDQAIN SQPSLNGMTQ ESINNYTTKR REAQNIASSA DTIINNGDAS
IEQITENKIR VEEATNALNE AKQHLTADTT SLKTEVRKLS RRGDTNNKKP SSVSAYNNTI
HSLQSEITQT ENRANTIINK PIRSVEEVNN ALHEVNQLNQ RLTDTINLLQ PLANKESLKE
ARNRLESKIN ETVQTDGMTQ QSVENYKQAK IKAQNESSIA QTLINNGDAS DQEVSTEIEK
LNQKLSELTN SINHLTVNKE PLETAKNQLQ ANIDQKPSTD GMTQQSVQSY ERKLQEAKDK
INSINNVLAN NPDVNAIRTN KVETEQINNE LTQAKQGLTV DKQPLINAKT ALQQSLDNQP
STTGMTEATI QNYNAKRQKA EQVIQNANKI IENAQPSVQQ VSDEKSKVEQ ALSELNNAKS
ALRADKQELQ QAYNQLIQPT DLNNKKPASI TAYNQRYQQF SNELNSTKTN TDRILKEQNP
SVADVNNALN KVREVQQKLN EARALLQNKE DNSALVRAKE QLQQAVDQVP STEGMTQQTK
DDYNSKQQAA QQEISKAQQV IDNGDATTQQ ISNAKTNVER ALEALNNAKT GLRADKEELQ
NAYNQLTQNI DTSGKTPASI RKYNEAKSRI QTQIDSAKNE ANSILTNDNP QVSQVTAALN
KIKAVQPELD KAIAMLKNKE NNNALVQAKQ QLQQIVNEVD PTQGMTTDTA NNYKSKKREA
EDEIQKAQQI INNGDATEQQ ITNETNRVNQ AINAINKAKN DLRADKSQLE NAYNQLIQNV
DTNGKKPASI QQYQAARQAI ETQYNNAKSE AHQILENSNP SVNEVAQALQ KVEAVQLKVN
DAIHILQNKE NNSALVTAKN QLQQSVNDQP LTTGMTQDSI NNYEAKRNEA QSAIRNAEAV
INNGDATAKQ ISDEKSKVEQ ALAHLNDAKQ QLTADTTELQ TAVQQLNRRG DTNNKKPRSI
NAYNKAIQSL ETQITSAKDN ANAVIQKPIR TVQEVNNALQ QVNQLNQQLT EAINQLQPLS
NNDALKAARL NLENKINQTV QTDGMTQQSI EAYQNAKRVA QNESNTALAL INNGDADEQQ
ITTETDRVNQ QTTNLTQAIN GLTVNKEPLE TAKTALQNNI DQVPSTDGMT QQSVANYNQK
LQIAKNEINT INNVLANNPD VNAIKTNKAE AERISNDLTQ AKNNLQVDTQ PLEKIKRQLQ
DEIDQGTNTD GMTQDSVDNY NDSLSAAIIE KGKVNKLLKR NPTVEQVKES VANAQQVIQD
LQNARTSLVP DKTQLQEAKN RLENSINQQT DTDGMTQDSL NNYNDKLAKA RQNLEKISKV
LGGQPTVAEI RQNTDEANAH KQALDTARSQ LTLNREPYIN HINNESHLNN AQKDNFKAQV
NSAPNHNTLE TIKNKADTLN QSMTALSESI ADYENQKQQE NYLDASNNKR QDYDNAVNAA
KGILNQTQSP TMSADVIDQK AEDVKRTKTA LDGNQRLEVA KQQALNHLNT LNDLNDAQRQ
TLTDTINHSP NINSVNQAKE KANTVNTAMT QLKQTIANYD DELHDGNYIN ADKDKKDAYN
NAVNNAKQLI NQSDANQAQL DPAEINKVTQ RVNTTKNDLN GNDKLAEAKR DANTTIDGLT
YLNEAQRNKA KENVGKASTK TNITSQLQDY NQLNIAMQAL RNSVNDVNNV KANSNYINED
NGPKEAYNQA VTHAQTLINA QSNPEMSRDV VNQKTQAVNT AHQNLHGQQK LEQAQSSANT
EIGNLPNLTN TQKAKEKELV NSKQTRTEVQ EQLNQAKSLD SSMGTLKSLV AKQPTVQKTS
VYINEDQPEQ SAYNDSITMG QTIINKTADP VLDKTLVDNA ISNISTKENA LHGEQKLTTA
KTEAINALNT LADLNTPQKE AIKTAINTAH TRTDVTAEQS KANQINSAMH TLRQNISDNE
SVTNESNYIN AEPEKQHAFT EALNNAKEIV NEQQATLDAN SINQKAQAIL TTKNALDGEE
QLRRAKENAD QEINTLNQLT DAQRNSEKGL VNSSQTRTEV ASQLAKAKEL NKVMEQLNHL
INGKNQMINS SKFINEDANQ QQAYSNAIAS AEALKNKSQN PELDKVTIEQ AINNINSAIN
NLNGEAKLTK AKEDAVASIN NLSGLTNEQK TKENQAVNGA QTRDQVANKL RDAEALDQSM
QTLRDLVNNQ NAIHSTSNYF NEDSTQKNTY DNAIDNGSTY ITGQHNPELN KSTIDQTISR
INTAKNDLHG VEKLQRDKGT ANQEIGQLGY LNDPQKSGEE SLVNGSNTRS EVEEHLNEAK
SLNNAMKQLR DKVAEKTNVK QSSDYINDST EHQRGYDQAL QEAENIINEI GNPTLNKSEI
EQKLQQLTDA QNALQGSHLL EEAKNNAITG INKLTALNDA QRQKAIENVQ AQQTIPAVNQ
QLTLDREINT AMQALRDKVG QQNNVHQQSN YFNEDEQPKH NYDNSVQAGQ TIIDKLQDPI
MNKNEIEQAI NQINTTQTAL SGENKLHTDQ ESTNRQIEGL SSLNTAQINA EKDLVNQAKT
RTDVAQKLAA AKEINSAMSN LRDGIQNKED IKRSSAYINA DPTKVTAYDQ ALQNAENIIN
ATPNVELNKA TIEQALSRVQ QAQQDLDGVQ QLANAKQQAT QTVNGLNSLN DGQKRELNLL
INSANTRTKV QEELNKATEL NHAMEALRNS VQNVDQVKQS SNYVNEDQPE QHNYDNAVNE
AQATINNNAQ PVLDKLAIER LTQTVNTTKD ALHGAQKLTQ DQQAAETGIR GLTSLNEPQK
NAEVAKVTAA TTRDEVRNIR QEATTLDTAM LGLRKSIKDK NDTKNSSKYI NEDHDQQQAY
DNAVNNAQQV IDETQATLSS DTINQLANAV TQAKSNLHGD TKLQHDKDSA KQTIAQLQNL
NSAQKHMEDS LIDNESTRTQ VQHDLTEAQA LDGLMGALKE SIKDYTNIVS NGNYINAEPS
KKQAYDAAVQ NAQNIINGTN QPTINKGNVT TATQTVKNTK DALDGDHRLE EAKNNANQTI
RNLSNLNNAQ KDAEKNLVNS ASTLEQVQQN LQTAQQLDNA MGELRQSIAK KDQVKADSKY
LNEDPQIKQN YDDAVQRVET IINETQNPEL LKANIDQATQ SVQNAEQALH GAEKLNQDKQ
TSSTELDGLT DLTDAQREKL REQINTSNSR DDIKQKIEQA KALNDAMKKL KEQVAQKDGV
HANSDYTNED SAQKDAYNNA LKQAEDIINN SSNPNLNAQD ITNALNNIKQ AQDNLHGAQK
LQQDKNTTNQ AIGNLNHLNQ PQKDALIQAI NGATSRDQVA EKLKEAEALD EAMKQLEDQV
NQDDQISNSS PFINEDSDKQ KTYNDKIQAA KEIINQTSNP TLDKQKIADT LQNIKDAVNN
LHGDQKLAQS KQDANNQLNH LDDLTEEQKN HFKPLINNAD TRDEVNKQLE IAKQLNGDMS
TLHKVINDKD QIQHLSNYIN ADNDKKQNYD NAIKEAEDLI HNHPDTLDHK ALQDLLNKID
QAHNELNGES RFKQALDNAL NDIDSLNSLN VPQRQTVKDN INHVTTLESL AQELQKAKEL
NDAMKAMRDS IMNQEQIRKN SNYTNEDLAQ QNAYNHAVDK INNIIGEDNA TMDPQIIKQA
TQDINTAING LNGDQKLQDA KTDAKQQITN FTGLTEPQKQ ALENIINQQT SRANVAKQLS
HAKFLNGKME ELKVAVAKAS LVRQNSNYIN EDVSEKEAYE QAIAKGQEII NSENNPTISS
TDINRTIQEI NDAEQNLHGD NKLRQAQEIA KNEIQNLDGL NSAQITKLIQ DIGRTTTKPA
VTQKLEEAKA INQAMQQLKQ SIADKDATLN SSNYLNEDSE KKLAYDNAVS QAEQLINQLN
DPTMDISNIQ AITQKVIQAK DSLHGANKLA QNQADSNLII NQSTNLNDKQ KQALNDLINH
AQTKQQVAEI IAQANKLNNE MGTLKTLVEE QSNVHQQSKY INEDPQVQNI YNDSIQKGRE
ILNGTTDDVL NNNKIADAIQ NIHLTKNDLH GDQKLQKAQQ DATNELNYLT NLNNSQRQSE
HDEINSAPSR TEVSNDLNHA KALNEAMRQL ENEVALENSV KKLSDFINED EAAQNEYSNA
LQKAKDIING VPSSTLDKAT IEDALLELQN ARESLHGEQK LQEAKNQAVA EIDNLQALNP
GQVLAEKTLV NQASTKPEVQ EALQKAKELN EAMKALKTEI NKKEQIKADS RYVNADSGLQ
ANYNSALNYG SQIIATTQPP ELNKDVINRA TQTIKTAENN LNGQSKLAEA KSDGNQSIEH
LQGLTQSQKD KQHDLINQAQ TKQQVDDIVN NSKQLDNSMN QLQQIVNNDN TVKQNSDFIN
EDSSQQDAYN HAIQAAKDLI TAHPTIMDKN QIDQAIENIK QALNDLHGSN KLSEDKKEAS
EQLQNLNSLT NGQKDTILNH IFSAPTRSQV GEKIASAKQL NNTMKALRDS IADNNEILQS
SKYFNEDSEQ QNAYNQAVNK AKNIINDQPT PVMANDEIQS VLNEVKQTKD NLHGDQKLAN
DKTDAQATLN ALNYLNQAQR GNLETKVQNS NSRPEVQKVV QLANQLNDAM KKLDDALTGN
DAIKQTSNYI NEDTSQQVNF DEYTDRGKNI VAEQTNPNMS PTNINTIADK ITEAKNDLHG
VQKLKQAQQQ SINTINQMTG LNQAQKEQLN QEIQQTQTRS EVHQVINKAQ ALNDSMNTLR
QSITDEHEVK QTSNYINETV GNQTAYNNAV DRVKQIINQT SNPTMNPLEV ERATSNVKIS
KDALHGEREL NDNKNSKTFA VNHLDNLNQA QKEALTHEIE QATIVSQVNN IYNKAKALNN
DMKKLKDIVA QQDNVRQSNN YINEDSTPQN MYNDTINHAQ SIIDQVANPT MSHDEIENAI
NNIKHAINAL DGEHKLQQAK ENANLLINSL NDLNAPQRDA INRLVNEAQT REKVAEQLQS
AQALNDAMKH LRNSIQNQSS VRQESKYINA SDAKKEQYNH AVREVENIIN EQHPTLDKEI
IKQLTDGVNQ ANNDLNGVEL LDADKQNAHQ SIPTLMHLNQ AQQNALNEKI NNAVTRTEVA
AIIGQAKLLD HAMENLEESI KDKEQVKQSS NYINEDSDVQ ETYDNAVDHV TEILNQTVNP
TLSIEDIEHA INEVNQAKKQ LRGKQKLYQT IDLADKELSK LDDLTSQQSS SISNQIYTAK
TRTEVAQAIE KAKSLNHAMK ALNKVYKNAD KVLDSSRFIN EDQPEKKAYQ QAINHVDSII
HRQTNPEMDP TVINSITHEL ETAQNNLHGD QKLAHAQQDA ANVINGLIHL NVAQREVMIN
TNTNATTREK VAKNLDNAQA LDKAMETLQQ VVAHKNNILN DSKYLNEDSK YQQQYDRVIA
DAEQLLNQTT NPTLEPYKVD IVKDNVLANE KILFGAEKLS YDKSNANDEI KHMNYLNNAQ
KQSIKDMISH AALRTEVKQL LQQAKILDEA MKSLEDKTQV VITDTTLPNY TEASEDKKEK
VDQTVSHAQA IIDKINGSNV SLDQVRQALE QLTQASENLD GDQRVEEAKV HANQTIDQLT
HLNSLQQQTA KESVKNATKL EEIATVSNNA QALNKVMGKL EQFINHADSV ENSDNYRQAD
DDKIIAYDEA LEHGQDIQKT NATQNETKQA LQQLIYAETS LNGFERLNHA RPRALEYIKS
LEKINNAQKS ALEDKVTQSH DLLELEHIVN EGTNLNDIMG ELANAIVNNY APTKASINYI
NADNLRKDNF TQAINNARDA LNKTQGQNLD FNAIDTFKDD IFKTKDALNG IERLTAAKSK
AEKLIDSLKF INKAQFTHAN DEIMNTNSIA QLSRIVNQAF DLNDAMKSLR DELNNQAFPV
QASSNYINSD EDLKQQFDHA LSNARKVLAK ENGKNLDEKQ IQGLKQVIED TKDALNGIQR
LSKAKAKAIQ YVQSLSYIND AQRHIAENNI HNSDDLSSLA NTLSKASDLD NAMKDLRDTI
ESNSTSVPNS VNYINADKNL QIEFDEALQQ ASATSSKTSE NPATIEEVLG LSQAIYDTKN
ALNGEQRLAT EKSKDLKLIK GLKDLNKAQL EDVTNKVNSA NTLTELSQLT QSTLELNDKM
KLLRDKLKTL VNPVKASLNY RNADYNLKRQ FNKALKEAKG VLNKNSGTNV NINDIQHLLT
QIDNAKDQLN GERRLKEHQQ KSEVFIIKEL DILNNAQKAA IINQIRASKD IKIINQIVDN
AIELNDAMQG LKEHVAQLTA TTKDNIEYLN ADEDHKLQYD YAINLANNVL DKENGTNKDA
NIIIGMIQNM DDARALLNGI ERLKDAQTKA HNDIKDTLKR QLDEIEHANA TSNSKAQAKQ
MVNEEARKAL SNINDATSND LVNQAKDEGQ SAIEHIHADE LPKAKLDANQ MIDQKVEDIN
HLISQNPNLS NEEKNKLISQ INKLVNGIKN EIQQAINKQQ IENATTKLDE VIETTKKLII
AKAEAKQMIK ELSQKKRDAI NNNTDLTPSQ KAHALADIDK TEKDALQHIE NSNSIDDINN
NKEHAFNTLA HIIIWDTDQQ PLVFELPELS LQNALVTSEV VVHRDETISL ESIIGAMTLT
DELKVNIVSL PNTDKVADHL TAKVKVILAD GSYVTVNVPV KVVEKELQIA KKDAIKTIDV
LVKQKIKDID SNNELTSTQR EDAKAEIERL KKQAIDKVNH SKSIKDIETV KRTDFEEIDQ
FDPKRFTLNK AKKDIITDVN TQIQNGFKEI ETIKGLTSNE KTQFDKQLTA LQKEFLEKVE
HAHNLVELNQ LQQEFNNRYK HILNQAHLLG EKHIAEHKLG YVVVNKTQQI LNNQSASYFI
KQWALDRIKQ IQLETMNSIR GAHTVQDVHK ALLQGIEQIL KVNVSIINQS FNDSLHNFNY
LHSKFDARLR EKDVANHIVQ TETFKEVLKG TGVEPGKINK ETQQPKLHKN DNDSLFKHLV
DNFGKTVGVI TLTGLLSSFW LVLAKRRKKE EEEKQSIKNH HKDIRLSDTD KIDPIVITKR
KIDKEEQIQN DDKHSIPVAK HKKSKEKQLS EEDIHSIPVV KRKQNSDNKD TKQKKVTSKK
KKTPQSTKKV VKTKKRSKK