ID   EBP2_XENLA              Reviewed;         312 AA.
AC   Q9I8J6;
DT   06-JUN-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2000, sequence version 1.
DT   03-AUG-2022, entry version 56.
DE   RecName: Full=Probable rRNA-processing protein EBP2;
DE   AltName: Full=Nucleolar protein p40-like protein;
GN   Name=ebna1bp2;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RA   Tanaka T.S., Ikenishi K.;
RT   "A possible role of the 38kDa protein, which is lacking in the gastrula-
RT   arrested, maternal-effect mutant embryos, in wild type Xenopus embryos:
RT   spatio-temporal distribution of the protein in wild-type embryos, and
RT   cloning a gene encoding it.";
RL   Submitted (MAY-2000) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Required for the processing of the 27S pre-rRNA.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC       {ECO:0000250|UniProtKB:Q99848}.
CC   -!- SIMILARITY: Belongs to the EBP2 family. {ECO:0000305}.
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DR   EMBL; AF272361; AAF81281.1; -; mRNA.
DR   RefSeq; NP_001167501.1; NM_001174030.1.
DR   AlphaFoldDB; Q9I8J6; -.
DR   SMR; Q9I8J6; -.
DR   GeneID; 100381119; -.
DR   KEGG; xla:100381119; -.
DR   CTD; 100381119; -.
DR   Xenbase; XB-GENE-998153; ebna1bp2.L.
DR   Proteomes; UP000186698; Chromosome 4L.
DR   Bgee; 100381119; Expressed in neurula embryo and 19 other tissues.
DR   GO; GO:0005730; C:nucleolus; ISS:UniProtKB.
DR   GO; GO:0042254; P:ribosome biogenesis; IEA:UniProtKB-KW.
DR   InterPro; IPR008610; Ebp2.
DR   PANTHER; PTHR13028; PTHR13028; 1.
DR   Pfam; PF05890; Ebp2; 1.
PE   2: Evidence at transcript level;
KW   Coiled coil; Nucleus; Reference proteome; Ribosome biogenesis.
FT   CHAIN           1..312
FT                   /note="Probable rRNA-processing protein EBP2"
FT                   /id="PRO_0000119995"
FT   REGION          1..32
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          211..312
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          140..176
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        220..237
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        241..255
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        282..312
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   312 AA;  35091 MW;  E1723786461E6068 CRC64;
     MLHHEDESSP ESDSDFDASE LTDKELQEAF SQGKLKPGLN VVLEGKKKPF NDASGLKQSL
     KDLKNELPWV ERLDVTVDPV VDTTGQNGQT DPNTSDINAE DDFQREMCFY RQAQAAVLYS
     LPRLRKLKVA TKRPDDYFAE MAKTDQHMQK IRHKLQLKQA SMEKSEKAKQ LRALRKYGKK
     VQVEVLQKRQ KEKSAMVTQI KKYQKGLSDK LDFLEGDQTP KKTPNKTGGS AAAQKAKNTP
     SAKRRYKDQK FGFGGKKKGS KGNTKGSYND VSGFRGSVAH GKGPHRPGKK GGKNANKRPG
     KNVRQKMKSK RR