ID   EBS1_ASHGO              Reviewed;         775 AA.
AC   Q751B2;
DT   22-NOV-2005, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 89.
DE   RecName: Full=Protein EBS1;
GN   Name=EBS1; OrderedLocusNames=AGL100W;
OS   Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
OS   (Yeast) (Eremothecium gossypii).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Eremothecium.
OX   NCBI_TaxID=284811;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX   PubMed=15001715; DOI=10.1126/science.1095781;
RA   Dietrich F.S., Voegeli S., Brachat S., Lerch A., Gates K., Steiner S.,
RA   Mohr C., Poehlmann R., Luedi P., Choi S., Wing R.A., Flavier A.,
RA   Gaffney T.D., Philippsen P.;
RT   "The Ashbya gossypii genome as a tool for mapping the ancient Saccharomyces
RT   cerevisiae genome.";
RL   Science 304:304-307(2004).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX   PubMed=23749448; DOI=10.1534/g3.112.002881;
RA   Dietrich F.S., Voegeli S., Kuo S., Philippsen P.;
RT   "Genomes of Ashbya fungi isolated from insects reveal four mating-type
RT   loci, numerous translocations, lack of transposons, and distinct gene
RT   duplications.";
RL   G3 (Bethesda) 3:1225-1239(2013).
CC   -!- FUNCTION: Involved in telomere maintenance. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}. Chromosome, telomere
CC       {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the EST1 family. {ECO:0000305}.
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DR   EMBL; AE016820; AAS54391.1; -; Genomic_DNA.
DR   RefSeq; NP_986567.1; NM_211629.1.
DR   AlphaFoldDB; Q751B2; -.
DR   SMR; Q751B2; -.
DR   STRING; 33169.AAS54391; -.
DR   PRIDE; Q751B2; -.
DR   EnsemblFungi; AAS54391; AAS54391; AGOS_AGL100W.
DR   GeneID; 4622866; -.
DR   KEGG; ago:AGOS_AGL100W; -.
DR   eggNOG; KOG2162; Eukaryota.
DR   HOGENOM; CLU_010068_0_0_1; -.
DR   InParanoid; Q751B2; -.
DR   OMA; EIIEYYF; -.
DR   Proteomes; UP000000591; Chromosome VII.
DR   GO; GO:0000781; C:chromosome, telomeric region; IEA:UniProtKB-SubCell.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   Gene3D; 1.25.40.10; -; 1.
DR   InterPro; IPR018834; DNA/RNA-bd_Est1-type.
DR   InterPro; IPR045153; Est1/Ebs1-like.
DR   InterPro; IPR019458; Est1_N.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   PANTHER; PTHR15696; PTHR15696; 1.
DR   Pfam; PF10374; EST1; 1.
DR   Pfam; PF10373; EST1_DNA_bind; 1.
DR   SUPFAM; SSF48452; SSF48452; 1.
PE   3: Inferred from homology;
KW   Chromosome; Nucleus; Reference proteome; Telomere.
FT   CHAIN           1..775
FT                   /note="Protein EBS1"
FT                   /id="PRO_0000086906"
FT   REGION          550..597
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   775 AA;  87953 MW;  89F73EA31DF4AC27 CRC64;
     MTLTPMEDKG IIPNFNDFKR QLAELLQSRS TVEDITLLQG FLQLVHSKTQ QWRGAEGLPA
     TPDLLDAVWK EIHYPIFKWF QQWRAHLLEA AEGGPQERTY ISFRRMNGKL NKIFKIIRQF
     YNGLVQQLFD RYDFGKLLPA GVIRELNVQS GGELQTLDDS SYFTILCVMS LQRCLLYLGC
     CHRYKCCCSK LSKRFHISDF DDSMRYFMLA KQIVPSVGET YLQEGLVYVQ TGNYGHAAYA
     FMRGSLSRMP TDAGIPNLES IVADASSGLF AKHQGILKRL RSKESDSNKL INREVLEFYF
     LALFSSVYAP ESWSKQGSDI RHCTEILFEK VRSRYARNVR LILQDVLLFI GGFDLVIKKA
     KAMGLNRSDT LPSNCTAFLE TAFDFFSHVI DSVVLKEWQS FDTWEYLALV RVICVWIKSH
     SIVTQFAHRH TQFCQSVAHL LNNILAHTEY QQLMDVEHRP KRDYFFQEDI MLKDFSAIGH
     TLSDFNDVDL FQMENLPDRL AGLVDDKLTA KEEGLLKLHA IVFIGKKFLA NNDVNIVWCD
     ESKRFNSLKP DVPLRTCSPP KAKTPPPSTS DYTPAGAKQT KKSKPKRNSR RVQSLSSLEA
     KLMERKGLRQ SVAEGRVYSG CSVPAAPMSF DVAPSAHLYQ DRAAGTSATQ EAATYYNQGY
     NGPMQLGSTE ILNSRSPSGN NRIAFHPSHQ AYMQMIQTPQ PQAWPTAYGH NAYYSQPTQH
     PYPMSSQLAQ FQNGPIPFVA GPYAMYMPPP GPGMVVLNNG HPMIPNESPP QQHYP