ECDD_ECO57
ID ECDD_ECO57 Reviewed; 78 AA.
AC Q8X7Z8; A0A0H3JNG9; Q7ABA8;
DT 25-APR-2018, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2002, sequence version 1.
DT 03-AUG-2022, entry version 100.
DE RecName: Full=Protein EcdD {ECO:0000305|PubMed:15979273};
DE AltName: Full=Phenolic acid decarboxylase subunit D {ECO:0000303|PubMed:15979273};
DE Short=PAD {ECO:0000303|PubMed:15979273};
GN Name=ecdD {ECO:0000303|PubMed:15979273};
GN OrderedLocusNames=ECs3591 {ECO:0000312|EMBL:BAB37014.1}, Z4045;
OS Escherichia coli O157:H7.
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=83334;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=O157:H7 / Sakai / RIMD 0509952 / EHEC {ECO:0000312|EMBL:BAB37014.1,
RC ECO:0000312|Proteomes:UP000000558};
RX PubMed=11258796; DOI=10.1093/dnares/8.1.11;
RA Hayashi T., Makino K., Ohnishi M., Kurokawa K., Ishii K., Yokoyama K.,
RA Han C.-G., Ohtsubo E., Nakayama K., Murata T., Tanaka M., Tobe T., Iida T.,
RA Takami H., Honda T., Sasakawa C., Ogasawara N., Yasunaga T., Kuhara S.,
RA Shiba T., Hattori M., Shinagawa H.;
RT "Complete genome sequence of enterohemorrhagic Escherichia coli O157:H7 and
RT genomic comparison with a laboratory strain K-12.";
RL DNA Res. 8:11-22(2001).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=O157:H7 / EDL933 / ATCC 700927 / EHEC {ECO:0000312|EMBL:AAG57844.1};
RX PubMed=11206551; DOI=10.1038/35054089;
RA Perna N.T., Plunkett G. III, Burland V., Mau B., Glasner J.D., Rose D.J.,
RA Mayhew G.F., Evans P.S., Gregor J., Kirkpatrick H.A., Posfai G.,
RA Hackett J., Klink S., Boutin A., Shao Y., Miller L., Grotbeck E.J.,
RA Davis N.W., Lim A., Dimalanta E.T., Potamousis K., Apodaca J.,
RA Anantharaman T.S., Lin J., Yen G., Schwartz D.C., Welch R.A.,
RA Blattner F.R.;
RT "Genome sequence of enterohaemorrhagic Escherichia coli O157:H7.";
RL Nature 409:529-533(2001).
RN [3]
RP FUNCTION.
RC STRAIN=O157:H7 / EDL933 / ATCC 700927 / EHEC;
RX PubMed=15979273; DOI=10.1016/j.ygeno.2005.05.002;
RA Lupa B., Lyon D., Gibbs M.D., Reeves R.A., Wiegel J.;
RT "Distribution of genes encoding the microbial non-oxidative reversible
RT hydroxyarylic acid decarboxylases/phenol carboxylases.";
RL Genomics 86:342-351(2005).
CC -!- FUNCTION: Involved in the non-oxidative decarboxylation and
CC detoxification of phenolic derivatives under anaerobic conditions,
CC however the precise biochemical function in metabolism of phenolic acid
CC is unknown. {ECO:0000269|PubMed:15979273}.
CC -!- MISCELLANEOUS: It is not known, if phenolic acid decarboxylase forms a
CC complex composed of EdcB, EdcC and EdcD. The term subunit is often used
CC in reference to the operon, however there is no experimental evidence
CC to prove the existence of the complex. {ECO:0000305}.
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DR EMBL; AE005174; AAG57844.1; -; Genomic_DNA.
DR EMBL; BA000007; BAB37014.1; -; Genomic_DNA.
DR PIR; G91077; G91077.
DR PIR; H85922; H85922.
DR RefSeq; NP_311618.1; NC_002695.1.
DR RefSeq; WP_000562982.1; NZ_SWKA01000005.1.
DR AlphaFoldDB; Q8X7Z8; -.
DR SMR; Q8X7Z8; -.
DR STRING; 155864.EDL933_3906; -.
DR EnsemblBacteria; AAG57844; AAG57844; Z4045.
DR EnsemblBacteria; BAB37014; BAB37014; ECs_3591.
DR GeneID; 58463091; -.
DR GeneID; 914687; -.
DR KEGG; ece:Z4045; -.
DR KEGG; ecs:ECs_3591; -.
DR PATRIC; fig|386585.9.peg.3754; -.
DR eggNOG; ENOG5032SBW; Bacteria.
DR HOGENOM; CLU_180856_1_1_6; -.
DR OMA; EGAWEVY; -.
DR Proteomes; UP000000558; Chromosome.
DR Proteomes; UP000002519; Chromosome.
DR GO; GO:0019439; P:aromatic compound catabolic process; IEA:UniProtKB-KW.
DR GO; GO:0009636; P:response to toxic substance; IEA:UniProtKB-KW.
PE 4: Predicted;
KW Aromatic hydrocarbons catabolism; Detoxification; Reference proteome.
FT CHAIN 1..78
FT /note="Protein EcdD"
FT /id="PRO_0000444037"
SQ SEQUENCE 78 AA; 9180 MW; CE168AB016C31417 CRC64;
MICPRCADEQ IEVMAKSPVK DVWTVYQCQH CLYTWRDTEP LRRTSREHYP EAFRMTQKDI
DDAPMVPSIP PLLAEGKR