ID   ECD_SCHPO               Reviewed;         590 AA.
AC   Q9US49;
DT   16-NOV-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2000, sequence version 1.
DT   25-MAY-2022, entry version 114.
DE   RecName: Full=Protein ecdysoneless homolog {ECO:0000250|UniProtKB:Q9W032};
DE   AltName: Full=Suppressor of GCR two {ECO:0000250|UniProtKB:O95905};
DE            Short=sgt1 {ECO:0000303|PubMed:16408318};
GN   Name=sgt1 {ECO:0000312|PomBase:SPAC1002.10c}; ORFNames=SPAC1002.10c;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
RN   [2]
RP   SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX   PubMed=16823372; DOI=10.1038/nbt1222;
RA   Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA   Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA   Yoshida M.;
RT   "ORFeome cloning and global analysis of protein localization in the fission
RT   yeast Schizosaccharomyces pombe.";
RL   Nat. Biotechnol. 24:841-847(2006).
RN   [3]
RP   FUNCTION, AND SUBCELLULAR LOCATION.
RX   PubMed=16408318; DOI=10.1002/yea.1336;
RA   Kainou T., Shinzato T., Sasaki K., Mitsui Y., Giga-Hama Y., Kumagai H.,
RA   Uemura H.;
RT   "Spsgt1, a new essential gene of Schizosaccharomyces pombe, is involved in
RT   carbohydrate metabolism.";
RL   Yeast 23:35-53(2006).
CC   -!- FUNCTION: Involved in the regulation of carbohydrate metabolism. May
CC       act as a transcription factor. {ECO:0000269|PubMed:16408318}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm. Nucleus.
CC   -!- SIMILARITY: Belongs to the ECD family. {ECO:0000305}.
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DR   EMBL; CU329670; CAB65610.1; -; Genomic_DNA.
DR   RefSeq; NP_593497.1; NM_001018931.2.
DR   AlphaFoldDB; Q9US49; -.
DR   BioGRID; 279694; 1.
DR   STRING; 4896.SPAC1002.10c.1; -.
DR   iPTMnet; Q9US49; -.
DR   MaxQB; Q9US49; -.
DR   PaxDb; Q9US49; -.
DR   PRIDE; Q9US49; -.
DR   EnsemblFungi; SPAC1002.10c.1; SPAC1002.10c.1:pep; SPAC1002.10c.
DR   GeneID; 2543266; -.
DR   KEGG; spo:SPAC1002.10c; -.
DR   PomBase; SPAC1002.10c; sgt1.
DR   VEuPathDB; FungiDB:SPAC1002.10c; -.
DR   eggNOG; KOG2406; Eukaryota.
DR   HOGENOM; CLU_006241_2_0_1; -.
DR   InParanoid; Q9US49; -.
DR   OMA; DYRVWIH; -.
DR   PhylomeDB; Q9US49; -.
DR   PRO; PR:Q9US49; -.
DR   Proteomes; UP000002485; Chromosome I.
DR   GO; GO:0005829; C:cytosol; HDA:PomBase.
DR   GO; GO:0005634; C:nucleus; IDA:PomBase.
DR   GO; GO:0070990; F:snRNP binding; ISS:PomBase.
DR   GO; GO:0045292; P:mRNA cis splicing, via spliceosome; ISS:PomBase.
DR   InterPro; IPR010770; Ecd.
DR   PANTHER; PTHR13060; PTHR13060; 2.
DR   Pfam; PF07093; SGT1; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Nucleus; Reference proteome; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..590
FT                   /note="Protein ecdysoneless homolog"
FT                   /id="PRO_0000220848"
FT   REGION          445..464
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   590 AA;  68157 MW;  1B0D7A283EB0294C CRC64;
     MSNLGNNITE RIESDCISQN ECRIDVYFSE KEKESTEASI NMFLAELERL QLEYGKEHIW
     QNEELNLQRV EYQGKDCILG ITNFGDCIDD EWYIVWLLRE ASKAVKSAFV RIIDEDGEFL
     LIEAALSLPK WIDEDNSDYR VWIHNGEVII LRPEDEFLKK MNRCPPLTRE QAIFQISSGS
     NLYTSREVND SISQRLKKFP KAANVKLRAI CTVPRKIVHV LQKNKNLISS AVNAFYYRDP
     IDENYCDRMS KFNQNDLVTT TITFTPLLYA QLYQQRCKTF RPFHLPSDVH SLDYERAILG
     MKLSCGFEIL YNSKENVEKR TEIDEYLQIQ PLPTDEDIKK IPLIEDDTSF MNVNPDELEE
     LLEKKLNSFC DDFGDDERSG FDNTDHDNTL VGEEEMVPGN HGGKSINEEI TKNKQKQNFN
     ESDLKNMASR IETFINDEAS NNHREDFYGV KNSDTDTDSD SLADSDDEIF LNRNQGIDEV
     EFDETKFYDL LKGKDGKYQN QDVDEFSSGN EDEMDIPGDA NMEEYMRAMD EELYGGLRGR
     DEGLEGIDDK DIDLNLMKNI IEGIEANPDL YGGPISTLLN SLKIQIPREK