ECFT1_LISM1
ID ECFT1_LISM1 Reviewed; 266 AA.
AC D2NWE2;
DT 31-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT 02-MAR-2010, sequence version 1.
DT 25-MAY-2022, entry version 46.
DE RecName: Full=Energy-coupling factor transporter transmembrane protein EcfT 1 {ECO:0000255|HAMAP-Rule:MF_01461};
DE Short=ECF transporter T component EcfT 1 {ECO:0000255|HAMAP-Rule:MF_01461};
GN Name=ecfT1 {ECO:0000255|HAMAP-Rule:MF_01461};
GN OrderedLocusNames=LM5578_0226;
OS Listeria monocytogenes serotype 1/2a (strain 08-5578).
OC Bacteria; Firmicutes; Bacilli; Bacillales; Listeriaceae; Listeria.
OX NCBI_TaxID=653938;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=08-5578;
RX PubMed=20167121; DOI=10.1186/1471-2164-11-120;
RA Gilmour M.W., Graham M., Van Domselaar G., Tyler S., Kent H.,
RA Trout-Yakel K.M., Larios O., Allen V., Lee B., Nadon C.;
RT "High-throughput genome sequencing of two Listeria monocytogenes clinical
RT isolates during a large foodborne outbreak.";
RL BMC Genomics 11:120-120(2010).
CC -!- FUNCTION: Transmembrane (T) component of an energy-coupling factor
CC (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF
CC transporter provides the energy necessary to transport a number of
CC different substrates. {ECO:0000255|HAMAP-Rule:MF_01461}.
CC -!- SUBUNIT: Forms a stable energy-coupling factor (ECF) transporter
CC complex composed of 2 membrane-embedded substrate-binding proteins (S
CC component), 2 ATP-binding proteins (A component) and 2 transmembrane
CC proteins (T component). May be able to interact with more than 1 S
CC component at a time (By similarity). {ECO:0000255|HAMAP-Rule:MF_01461}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_01461};
CC Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_01461}.
CC -!- SIMILARITY: Belongs to the energy-coupling factor EcfT family.
CC {ECO:0000255|HAMAP-Rule:MF_01461}.
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DR EMBL; CP001602; ADB66983.1; -; Genomic_DNA.
DR RefSeq; WP_012951121.1; NC_013766.2.
DR AlphaFoldDB; D2NWE2; -.
DR SMR; D2NWE2; -.
DR KEGG; lmn:LM5578_0226; -.
DR HOGENOM; CLU_056469_2_2_9; -.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR HAMAP; MF_01461; EcfT; 1.
DR InterPro; IPR003339; ABC/ECF_trnsptr_transmembrane.
DR InterPro; IPR024919; EcfT.
DR Pfam; PF02361; CbiQ; 1.
PE 3: Inferred from homology;
KW Cell membrane; Membrane; Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..266
FT /note="Energy-coupling factor transporter transmembrane
FT protein EcfT 1"
FT /id="PRO_0000408998"
FT TRANSMEM 33..53
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01461"
FT TRANSMEM 73..93
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01461"
FT TRANSMEM 107..127
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01461"
FT TRANSMEM 152..172
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01461"
FT TRANSMEM 243..263
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01461"
SQ SEQUENCE 266 AA; 29826 MW; 8FE427EAFB6E1A8D CRC64;
MIEKLILGRF VPGESLIHGL DARTKLLAGF YYIGILFLAN NWWTYALMVL FTLMVVQMTG
IKLKVFIKGV KPLIWLILFT VVMQILFASG GTIYFDWGPF TISSFGLLNG VFVFLRFVLI
IIMSTVITLT TTPMNLTDAI AYILRPFAVL KVPVNDIALM ISVALRFIPT LMGETDKIMK
AQRARGVDFG EGNLFEQMKV VVPIFIPLFV SSFNRAEELA DAMEARGYQG GEGRTRFRIL
HWHFGDLIAA CVMILLTAGL VILRTS
