ID   ECFT_EXIS2              Reviewed;         263 AA.
AC   B1YH82;
DT   31-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT   20-MAY-2008, sequence version 1.
DT   25-MAY-2022, entry version 75.
DE   RecName: Full=Energy-coupling factor transporter transmembrane protein EcfT {ECO:0000255|HAMAP-Rule:MF_01461};
DE            Short=ECF transporter T component EcfT {ECO:0000255|HAMAP-Rule:MF_01461};
GN   Name=ecfT {ECO:0000255|HAMAP-Rule:MF_01461}; OrderedLocusNames=Exig_0127;
OS   Exiguobacterium sibiricum (strain DSM 17290 / CIP 109462 / JCM 13490 /
OS   255-15).
OC   Bacteria; Firmicutes; Bacilli; Bacillales;
OC   Bacillales Family XII. Incertae Sedis; Exiguobacterium.
OX   NCBI_TaxID=262543;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 17290 / CIP 109462 / JCM 13490 / 255-15;
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA   Bruce D., Goodwin L., Pitluck S., Kiss H., Chertkov O., Monk C.,
RA   Brettin T., Detter J.C., Han C., Kuske C.R., Schmutz J., Larimer F.,
RA   Land M., Hauser L., Kyrpides N., Mikhailova N., Vishnivetskaya T.,
RA   Rodrigues D.F., Gilichinsky D., Tiedje J., Richardson P.;
RT   "Complete sequence of chromosome of Exiguobacterium sibiricum 255-15.";
RL   Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Transmembrane (T) component of an energy-coupling factor
CC       (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF
CC       transporter provides the energy necessary to transport a number of
CC       different substrates. {ECO:0000255|HAMAP-Rule:MF_01461}.
CC   -!- SUBUNIT: Forms a stable energy-coupling factor (ECF) transporter
CC       complex composed of 2 membrane-embedded substrate-binding proteins (S
CC       component), 2 ATP-binding proteins (A component) and 2 transmembrane
CC       proteins (T component). May be able to interact with more than 1 S
CC       component at a time (By similarity). {ECO:0000255|HAMAP-Rule:MF_01461}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_01461};
CC       Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_01461}.
CC   -!- SIMILARITY: Belongs to the energy-coupling factor EcfT family.
CC       {ECO:0000255|HAMAP-Rule:MF_01461}.
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DR   EMBL; CP001022; ACB59614.1; -; Genomic_DNA.
DR   RefSeq; WP_012369039.1; NC_010556.1.
DR   AlphaFoldDB; B1YH82; -.
DR   SMR; B1YH82; -.
DR   STRING; 262543.Exig_0127; -.
DR   EnsemblBacteria; ACB59614; ACB59614; Exig_0127.
DR   KEGG; esi:Exig_0127; -.
DR   eggNOG; COG0619; Bacteria.
DR   HOGENOM; CLU_056469_2_2_9; -.
DR   OMA; MKAQMSR; -.
DR   OrthoDB; 1479665at2; -.
DR   Proteomes; UP000001681; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01461; EcfT; 1.
DR   InterPro; IPR003339; ABC/ECF_trnsptr_transmembrane.
DR   InterPro; IPR024919; EcfT.
DR   Pfam; PF02361; CbiQ; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..263
FT                   /note="Energy-coupling factor transporter transmembrane
FT                   protein EcfT"
FT                   /id="PRO_0000408988"
FT   TRANSMEM        22..42
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01461"
FT   TRANSMEM        69..89
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01461"
FT   TRANSMEM        105..125
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01461"
FT   TRANSMEM        243..263
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01461"
SQ   SEQUENCE   263 AA;  29594 MW;  A5D30DF8715F5B55 CRC64;
     MIVGQHIPGT SYLHRSSAVA KIIFAFCFIP LVFLANNAAT NIFLLLFTFF ALASSKLPIR
     YVLKGLRPIL FLIIFTFIIQ LLFTREGAVL FEFGWFKIYE EGLRLAIIVS LRFFYLVSIT
     TLVTLTTSPI ELTDAIELLL KPFKVVRVPT HEIALMLSIS LRFLPTLAEE TEKIMKAQQA
     RGVDLSAGPI KERLRAIIPL LIPLFISAFK RAEDLATAME ARGYRGGEGR TRLRESKWTT
     RDTGLILLLV ALGLLLVYLR GGF